Europaisches Patentamt
European Patent Office
© Publication number:
Office europeen des brevets
EUROPEAN
PATENT
493
A3
APPLICATION
int. Ci.5; C07J
© Application number: 90106971.6
0 393
9/00, A61 K 3 1 / 5 7 5
@ Date of filing: 11.04.90
®
© Applicant: GIULIANI S.p.A.
Via P. Palagi, 2
1-20129 Milano(IT)
Priority: 17.04.89 IT 2017089
@ Date of publication of application:
24.10.90 Bulletin 90/43
©
Designated Contracting States:
AT BE CH DE DK ES FR GB GR IT LI LU NL SE
©
Date of deferred publication of the search report:
27.05.92 Bulletin 92/22
@ Inventor: Pellicciari, Roberto
Via Palagi 2
1-20129 Milano(IT)
Inventor: Roda, Aldo
Via Palagi 2
1-20129 Milano(IT)
Inventor: Frigerio, Giuliano
Via Palagi 2
1-20129 Milano(IT)
©
Representative: Minoja, Fabrizio
Studio Consulenza Brevettuale Via Rossini,
8
1-20122 Milano(IT)
© Fluorinated bile acid derivatives, processes for the preparation thereof and pharmaceutical
compositions containing them.
© A compounds of general formula I
COOH
*
„
m
oo
O
^
LU
X£\
HOxx \ ^ ^
\\ ^
nOH
f
wherein Ri is hydrogen or hydroxy, and the hydroxy group at the 7-position can be either in or /3 configuration,
are valuable in human therapy. Compounds I can be prepared by fluorination of the suitably protected 6
-hydroxy-7-keto-derivatives.
Rank Xerox (UK) Business Services
European Patent
Office
Application Number
EUROPEAN SEARCH R E P O R T
EP
DOCUMENTS CONSIDERED TO BE RELEVANT
Relevant
Citation of document with indication, where appropriate,
Category
to claim
of relevant passages
DRUGS
1.6
vol. 21, 1981, AUSTRALIA
pages 90 - 119;
J. H. ISER ET AL: 'Chenodeoxychollc Acid: A
Review of Its Pharmacological Properties and
Therapeutic Use1
* the whole document *
90 10 6971
CLASSIFICATION OF THE
APPLICATION qnt. CI.S )
C07J9/00
A61K3 1/575
TECHNICAL FIELDS
SEARCHED ant. CI.5 )
C07J
A61K
The present search report has been drawn up for all claims
Date of aunpletMi ofthe search
Place of iearch
30 MARCH 1992
THE HAGUE
CATEGORY OF CITED DOCUMENTS
X : particularly relevant if taken alone
Y: particularly relevant if combined with another
document of the same category
A : technological background
O : non-written disclosure
P : intermediate document
Exaatfaer
WATCHORN P.W.
T : theory or principle underlying the invention
E : earlier patent document, but published on, or
after the filing date
D : document cited in the application
L : document cited for other reasons
&: member of the same patent family, corresponding
document