giovedì 21 gennaio 2016 ore 14:00, aula 2025, edificio U3 Targeting Cancer Pathways: The Tumor Microenvironment Rakesh K. Jain, Ph.D. – Harvard Medical School/MGH, Boston, MA Padmanee Sharma, M.D., Ph.D. – MD Anderson Cancer Center, Houston, TX This webinar is the second in a series focusing on the cancer pathways that support tumor development, the emerging research in identifying and targeting these pathways, and innovations in the development of increasingly effective cancer therapy options. Recent advances in our understanding of cancer have revealed that the disease cannot be understood through simple analysis of genetic mutations within cancerous cells. Instead, tumors should be considered complex tissues in which the cancer cells communicate with the surrounding cellular microenvironment and evolve traits that promote their own survival. Here, we will explore how the tumor microenvironment promotes oncogenic progression, while protecting the tumor from therapeutic intervention. By better understanding the tumor microenvironment we can develop strategies and treatment options to neutralize its oncogenic influence and more effectively attack the tumor itself. During the webinar, the expert speakers will: – Discuss the importance of understanding the tumor microenvironment and how it interacts with normal cells – Highlight what can be learned from the tumor microenvironment that might allow better, more effective therapeutics to be developed – Explain how the abnormal microenvironment impacts anti-cancer drugs and how manipulating it with antiangiogenics can improve therapeutic outcomes. Durata del Webinar: 57 min Si consiglia di portare le proprie cuffie per avere una migliore qualità audio I BtBs-Webinar sono seminari online aperti a tutti, non hanno bisogno di essere prenotati e non bisogna portare il proprio computer. coordinatore: Reinaldo Alvarez, [email protected], tel. 3330