School of Science & Technology
Protecting pancreatic b-cell function in Type 2 diabetes
Type 2 diabetes is a major public health and economic burden that is associated with obesity and poor diet. The
resulting chronic hyperglycaemia can have damaging effects on a number of organs and tissues, including the
pancreas. One proposed mechanism by which this occurs is through increased oxidative stress.
This project will investigate how increased / chronic glucose levels affect pancreatic b-cell function and will identify
potential molecular mechanisms that can moderate this. This will include an assessment of the role of
mitochondrial dysfunction and whether nutritional supplements, such as antioxidants, can protect against
glucotoxicty and moderate disease pathology.
This project has been selected for consideration for a fully-funded Vice-Chancellor’s PhD bursary at Nottingham
Trent University, twelve PhD projects will be funded across the University in 2014.
Entry requirement
Candidates will be expected to hold an MRes/MSc (with distinction) in a Biomedical / Molecular Bioscience related
discipline or 1st class degree in a Biomedical/Molecular Bioscience related discipline. Candidates will be expected
to have extensive Bioscience laboratory skills gained during their degree or research experience.
Award
The studentships will pay UK/EU fees and provide a maintenance stipend linked to the RCUK rate (currently
£13,726 per annum) for up to three years. Applications from non-EU students are welcome, but a successful
candidate would be responsible for paying the difference between non-EU and UK/EU fees. (Fees for 2013/14 are
£11,600 for non-EU students and £3,900 for UK/EU students.)
Eligibility
Applications can be accepted from UK/EU and also International students. The minimum English language
proficiency requirement for candidates who have not undertaken a higher degree at a UK HE institution is IELTS 6.5
(with no element to be below 6.0) or TOEFL 560/iBT 94 - 95.
Applying
For informal enquiries about the studentship, please contact Dr. Luigi De Girolamo – [email protected]
To download an application pack, please Order literature from the Graduate School website.
Please return completed application forms, with copies of academic certificates to: [email protected]
The closing date for receipt of completed application forms is 09:00 Friday 24 January 2014.
Application by CV only will not be accepted.