February 2004 Table of Contents This Month in Haematologica Hemophagocytic Lymphomas 129-132 February 2004 183-188 Editorials, Comments & Views 133-137 137-138 The idiopathic hypereosinophilic syndrome and eosinophilic leukemias Barbara J. Bain Longitudinal follow-up of patients with Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis Shinsaku Imashuku, Tomoko Teramura, Hisamichi Tauchi, Yasushi Ishida, Yoshiko Otoh, Machiko Sawada, Haruki Tanaka, Arata Watanabe, Yasuhiro Tabata, Akira Morimoto, Shigeyoshi Hibi, Jan-Inge Henter Disorders of Hemostasis 189-194 Towards a rational treatment of essential thrombocythemia, despite limited evidence and old prejudices Mario Cazzola Use of implantable venous access devices in children with severe hemophilia: benefits and burden Karin Van Dijk, Johanna G. Van Der Bom, Klaas N.M.A. Bax, David C. Van Der Zee, Marijke H. van Den Berg Thrombosis Research Papers 195-200 Association of factor V deficiency with factor V HR2 Elena M. Faioni, Giancarlo Castaman, Daniela Asti, Federico Lussana, Francesco Rodeghiero 201-206 The contribution of factor V Leiden and prothrombin G20210A mutation to the risk of central venous catheter-related thrombosis Cornelis J. van Rooden, Frits R. Rosendaal, A. Edo Meinders, Jacques A. van Oostayen, Felix J. M. van der Meer, Menno V. Huisman 207-214 Mucormycosis in hematologic patients Livio Pagano, Massimo Offidani, Luana Fianchi, Annamaria Nosari, Anna Candoni, Marco Piccardi, Laura Corvatta, Domenico D’Antonio, Corrado Girmenia, Pietro Martino, Albano Del Favero and GIMEMA (Gruppo Italiano Malattie EMatologiche dell'Adulto) Infection Program Acute Lymphoblastic Leukemia 139-144 Methylenetetrahydrofolate reductase genotypes do not play a role in acute lymphoblastic leukemia pathogenesis in the Italian population Patrizia Chiusolo, Giovanni Reddiconto, Giuseppe Cimino, Simona Sica, Alessia Fiorini, Giuliana Farina, Antonella Vitale, Federica Sorà, Luca Laurenti, Francesco Bartolozzi, Paola Fazi, Franco Mandelli, Giuseppe Leone Thrombosis Infectious Disorders Acute Lymphoblastic Leukemia 145-153 GIMEMA ALL - Rescue 97: a salvage strategy for primary refractory or relapsed adult acute lymphoblastic leukemia Andrea Camera, Luciana Annino, Federico Chiurazzi, Paola Fazi, Nicola Cascavilla, Francesco Fabbiano, Filippo Marmont, Francesco Di Raimondo, Anna Recchia, Marco Vignetti, Bruno Rotoli, Franco Mandelli for the GIMEMA Group 154-164 Aberrant promoter methylation of multiple genes throughout the clinico-pathologic spectrum of B-cell neoplasia Davide Rossi, Daniela Capello, Annunziata Gloghini, Silvia Franceschetti, Marco Paulli, Kishor Bhatia, Giuseppe Saglio, Umberto Vitolo, Stefano A. Pileri, Manel Esteller, Antonino Carbone, Gianluca Gaidano Malignant Lymphomas Decision Making & Problem Solving Chronic Myeloprolifertive Disorders 215-232 Chronic Lymphoproliferatiove Disorders 165-173 Genetic characterization of the Sézary’s syndrome by conventional cytogenetics and cross-species color banding fluoresceent in situ hybridization Blanca Espinet, Marta Salido, Ramon M. Pujol, Lourdes Florensa, Fernando Gallardo, Alícia Domingo, Octavio Servitje, Teresa Estrach, Pilar García-Muret, Soledad Woessner, Sergi Serrano, Francesc Solé Multiple Myeloma 174-182 Osteopontin is an adhesive factor for myeloma cells and is found in increased levels in plasma from patients with multiple myeloma Therese Standal, Henrik Hjorth-Hansen, Thomas Rasmussen, Inger Marie Dahl, Stig Lenhoff, Anne-Tove Brenne, Carina Seidel, Vadim Baykov, Anders Waage, Magne Børset, Anders Sundan Practice guidelines for the therapy of essential thrombocythemia. A statement from the Italian Society of Hematology, the Italian Society of Experimental Hematology and the Italian Group for Bone Marrow Transplantation Tiziano Barbui, Giovanni Barosi, Alberto Grossi, Luigi Gugliotta, Lucio N. Liberato, Monia Marchetti, Maria Gabriella Mazzucconi, Francesco Rodeghiero, Sante Tura Letters to the Editor Disorders of Erythropoiesis 233-234 Heart rate variability and ventricular late potentials in β-thalassemia major Ferdinando Franzoni, Fabio Galetta, Carmine Di Muro, Giuliana Buti, Ferdinando Pentimone, Gino Santoro Haematologica 2004; vol. 89; no. 2 - February 2004 (indexed by Current Contents/Life Sciences and in Faxon Finder and Faxon XPRESS, also available on diskette with abstracts) http://www.haematologica.org/ February 2004 Cytokines 234-236 236-237 Table of Contents Stem Cell Transplantation Circulating levels and promoter polymorphisms of interluekins-6 and 8 in pediatric cancer patients with fever and neutropenia Thomas Lehrnbecher, Gudrun Fleischhack, Mitra Hanisch, Frank Deinlein, Arne Simon, Toralf Bernig, Stephen J. Chanock, Thomas Klingebiel 249-251 Chronic Myeloproliferative Disorders 251-252 Heparin based anticoagulation during peripheral blood stem cell collection may increase the CD34+ cell yield Julián Sevilla, Marta González-Vicent, Sandra Fernández-Plaza, Luis Madero, Miguel Angel Díaz Infectious Disorders Imatinib mesylate can induce complete molecular remission in FIP1L1-PDGFR-α positive idiopathic hypereosinophilic syndrome Giovanni Martinelli, Michele Malagola, Emanuela Ottaviani, Gianantonio Rosti, Elena Trabacchi, Michele Baccarani Decrease of dual hepatitis B and C virus infections in children with cancer: changes in risk factors over 30 years Sylwia Koltan, Jan Styczynski, Mariusz Wysocki, Andrzej Koltan, Andrzej Kurylak, Robert Debski Chronic Myeloproliferative Disorders 238-239 Immunophenotypic evaluation of circulating T-cell clones in hypereosinophilic syndromes with or without abnormal CD3 and CD4 lymphocytes Renato Bassan, Giovanni Locatelli, Gianmaria Borleri, Anna Salvi, Tiziano Barbui Continuing Medical Education 253 A case of persistent eosinophilia 254 A case of leukocytosis with erythroderma 255 A case of abrupt pancytopenia 256 A woman with essential thrombocythemia Chronic Myeloproliferative Disorders 239-241 A further case of myeloproliferative syndrome with reciprocal translocation (8;13)(p11;q12) Rosangela Invernizzi, Chiara Benatti, Erica Travaglino, Margherita Girino, Paolo Bernasconi, Carlo Loni, Edoardo Ascari Chronic Myeloid Leukemia 241-243 c-myc expression in cell lines derived from chronic myeloid leukemia M. Teresa Gómez-Casares, Jose P. Vaqué, Angelina Lemes, Teresa Molero, M. Dolores Delgado, Javier León 243-245 Recombinant factor VIIa for the management of severe hemorrhages in patients with hematologic malignancies Paolo de Fabritiis, Teresa Dentamaro, Alessandra Picardi, Laura Cudillo, Mario Masi, Sergio Amadori Disorders of Hemostasis Chronic Myeloproliferative Disorders 245-247 Incidence of pulmonary hypertension in patients with chronic myeloproliferative disorders Vasilia Garypidou, Sofia Vakalopoulou, Dimokritos Dimitriadis, Konstantinos Tziomalos, George Sfikas, Vasilios Perifanis Stem Cell Transplantation 247-249 Clinical and practical value of metaphase fluorescent in situ hybridization in follow-up after allogeneic stem cell transplantation in chronic myeloid leukemia Tuija Lundán, Liisa Volin, Erkki Elonen, Kirsi Autio, Sakari Knuutila Haematologica 2004; vol. 89; no. 2 - February 2004 (indexed by Current Contents/Life Sciences and in Faxon Finder and Faxon XPRESS, also available on diskette with abstracts) http://www.haematologica.org/