Xxxxxxxxxxxxxxxx
55
th
:
understanding onc-OMICS
for patient-tailored cancer therapy
ACT
ABSTRISSION
SUBM DLINE
DEA
,
June 7
2013
Catanzaro
23 – 226 September 2013
1
55 Annual Meeting
Committee
th
of the
Italian Cancer Society
:
understanding onc-OMICS
for patient-tailored cancer therapy
Catanzaro
23 – 26 September 2013
CONGRESS VENUE
Università degli Studi “Magna Græcia” di Catanzaro
Viale Europa - 88100 Germaneto - Catanzaro
Villaggio Guglielmo Congress Center
Piazza Susanna, 1 - 88069 Copanello - Catanzaro
www.villaggioguglielmo.it
ORGANIZING SECRETARIAT
Adria Congrex Srl
Via Sassonia,
nia, 30 – 47922 Rimini RN
Ph. +39 0541 305811 – Fax +39 0541 305842
E-mail: [email protected]
Web site: www.adriacongrex.it/sic2013
SIC SEC
SECRETARIAT
Società
età Italiana
età
Itali
liana
na di Cancerologia
Can
Viaa G. Venezian, 1 – 220133 Milan
Ph. +39 02 2666895 – Fax +39 02 2664342
E-mail: [email protected]
Web site: www.cancerologia.it
2
SIC SCIENTIFIC BOARD
President
Riccardo Dolcetti (CRO-IRCCS, National Cancer Institute, Aviano, Pordenone, Italy)
President Elect
Silvia Giordano (Institute for Cancer Research and Treatment, University of Turin, Candiolo, Italy)
Board
Anna Bagnato (Regina Elena National Cancer Institute, Rome, Italy)
Vincenzo Bronte (University of Verona, Italy)
Maurizio D’Incalci (“Mario Negri” Institute for Pharmacological Research, Milan, Italy)
Nicola Normanno (National Cancer Institute “G. Pascale”, Naples, Italy)
Salvatore Pece (IFOM-IEO Campus, University of Milan, Italy)
Katia Scotlandi (Orthopaedic Rizzoli Institute, Bologna, Italy)
Gabriella Sozzi (IRCCS National Cancer Institute, Milan, Italy)
Stefania Tommasi (National Cancer Centre “Giovanni Paolo II”, Bari, Italy)
Giuseppe Viglietto (University of Magna Græcia, Catanzaro, Italy)
Past President
Alfredo Fusco (“Federico II” University, Naples, Italy)
Representative for Young Researchers
Chiara Gabellini (Regina Elena National Cancer Institute, Rome, Italy)
Pierlorenzo Pallante (Institute of Endocrinology and Experimental Oncology, CNR, Naples, Italy)
SCIENTIFIC AND ORGANIZING COMMITTEE
Scientific Coordinator
Giuseppe Viglietto (University of Magna Graecia, Catanzaro, Italy)
Local Scientific Committee
Gennaro Ciliberto (National Cancer Institute “G. Pascale”, Naples, Italy;
University of Magna Græcia, Catanzaro, Italy)
Francesco Saverio Costanzo (University of Magna Graecia, Catanzaro, Italy)
Gianni Cuda (University of Magna Græcia, Catanzaro, Italy)
Dolores Di Vizio (Cedars Sinai Medical Center, Los Angeles, CA, USA)
Marcello Maggiolini (University of Cosenza, Italy)
Giovanni Morrone (University of Magna Græcia, Catanzaro, Italy)
Pierosandro Tagliaferri (University of Magna Græcia, Catanzaro, Italy)
Pierfrancesco Tassone (University of Magna Græcia, Catanzaro, Italy)
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55 Annual Meeting
Speakers
th
of the
Italian Cancer Society
Monday 23 September
SCIENTIFIC PROGRAMME
VENUE: UNIVERSITY OF CATANZARO, AUDITORIUM
:
understanding onc-OMICS
for patient-tailored cancer therapy
Catanzaro
23 – 26 September 2013
Paolo Ascierto
National Cancer Institute G. Pascale, Naples, Italy
Giorgio Parmiani
IRCCS San Raffaele Hospital, Milan, Italy
Rosa Bernardi
IRCCS San Raffaele Hospital, Milan, Italy
Daniel Peeper
The Netherlands Cancer Institute, Amsterdam,
The Netherlands
Renzo Canetta
Bristol-Myers Squibb, Wallingford, CT, USA
John Quackenbush
Dana-Farber Cancer Institute, Boston, MA, USA
Ugo Cavallaro
European Institute of Oncology, Milan, Italy
Lucia Ricci Vitiani
ISS, Istituto Superiore di Sanità, Rome, Italy
Paola Chiarugi
University of Florence, Italy
Mercedes Robledo
Spanish National Cancer Centre (CNIO), Madrid, Spain
Francesca Demichelis
University of Trento, Italy
Mark A. Rubin
Weill Cornel Medical College, New York, NY, USA
Federica Di Nicolantonio
Institute for Cancer Research and Treatment,
Candiolo, Turin, Italy
Massimo Santoro
University of Naples, Italy
14.00 ‐ 14.30 OPENING CEREMONY
A. Quattrone (Magnifico Rettore Magna Graecia University, Catanzaro, Italy)
R. Dolcetti (SIC President, Aviano PN, Italy)
14.30 ‐ 15.30 OPENING LECTURE
Function-based screening for therapeutic targets in cancer
D. Peeper (Amsterdam, The Netherlands) Sponsored by EACR
15.30 - 17.30 NON CODING RNAS
15.30 - 16.00 MicroRNAs as targeted therapeutics and therapeutic targets in cancer
F.J. Slack (New Haven, USA)
16.00 - 16.30 MicroRNA and lung cancer
G. Sozzi (Milan, Italy)
Giulio Draetta
MD Anderson Cancer Center, Houston, TX, USA
Aldo Scarpa
University of Verona, Italy
Riccardo Fodde
Josephine Nefkens Institute Erasmus
University Medical Centre, Rotterdam, The Netherlands
Jean J. Schuringa
Faculty of Medical Sciences, Hematology,
Groningen, The Netherlands
Niels Frandsen
Exiqon, Vedbaek, Denmark
Salvatore Siena
Niguarda Ca’ Granda Hospital, Milan, Italy
Guido Franzoso
Imperial College, London, United Kingdom
Frank J. Slack
Yale University, New Haven, CT, USA
18.00 - 18.30 Cancer-selected targeting of the NF-ĸB pathway
G. Franzoso (London, UK)
Eric Holland
Memorial Sloan Kettering Cancer Center, New York, NY, USA
Gabriella Sozzi
IRCCS National Cancer Institute, Milan, Italy
18.30 – 19.00 Reciprocal metabolic deregulation of tumors and their stroma
P. Chiarugi (Florence, Italy)
Antonio Iavarone
Columbia University, New York, NY, USA
Henk J. Stunnemberg
Nijmegen Centre for Molecular Life Sciences,
Nijmegen, The Netherlands
19.00 - 19.30 Selected presentations
Norman J. Maitland
University of York, United Kingdom
Andreas Trumpp
Heidelberg Institute for Stem Cell Technology and
Experimental Medicine, Heidelberg, Germany
Francesco Marincola
National Institutes of Health, Bethesda, MD, USA
16.30 - 17.00 Role of MicroRNAs in progression and invasiveness of breast cancer
S. Volinia (Ferrara, Italy)
17.00 - 17.30 Selected presentations
18.00 ‐ 19.30 CANCER BIOCHEMISTRY AND METABOLISM
19.30
WELCOME COCKTAIL
21.30
Shuttle Bus from the University to Villaggio Gugliemo
Stefano Volinia
University of Ferrara, Italy
Maria Caterina Mione
Karlsruhe Institute of Technology,
Eggenstein-Leopoldshafen, Germany
Paolo Paoletti
GlaxoSmithKline, Collegeville, PA, USA
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5
55 Annual Meeting
Tuesday 24 September
th
of the
Italian Cancer Society
SCIENTIFIC PROGRAMME
VENUE: VILLAGGIO GUGLIELMO
Tuesday 24 September
SCIENTIFIC PROGRAMME
VENUE: VILLAGGIO GUGLIELMO
:
understanding onc-OMICS
for patient-tailored cancer therapy
Catanzaro
23 – 26 September 2013
8.00 ‐ 9.00
MEET‐THE‐EXPERT: INFORMAL ROUND‐TABLE@BREAKFAST
Parallel Sessions
ANIMAL MODELS E. Holland (New York, USA) - M. Mione (Eggenstein-Leopoldshafen, Germany)
CANCER STEM CELLS N. Maitland (York, United Kingdom) - R. Fodde (Rotterdam, The Netherlands)
14.00 ‐ 16.00 POSTER VIEWING
16.00 – 19.10 ADVANCED DIAGNOSTICS AND THERAPEUTICS
THE PHARMA’S VIEW
9.00 ‐ 13.00
CANCER GENOMICS AND EPIGENOMICS
9.00 - 9.30
The drivers of oncogenesis and master regulators of glioblastoma
A. Iavarone (New York, USA)
9.30 - 10.00
Next generation histopathological diagnosis: from genomics to clinical application
A. Scarpa (Verona, Italy)
10.00 - 10.30 From OMIC to the patient
M. Robledo (Madrid, Spain)
16.00 - 16.20 Functional validation of cancer genes
G. Draetta (Houston, USA)
16.20 - 16.40 LNA antisense oligonucleotides: promising drug development platform and
antisense tools for the study of RNA function in animals
N. Frandsen (Exiqon, Vedbaek, Denmark)
16.40 - 17.00 Challenges of drug discovery and development in the era of precision
medicine
P. Paoletti (GSK, Collegeville, USA)
10.30 - 11.00 Epigenomics: functionally indexing genomes in health and disease
H. Stunnemberg (Nijmegen, The Netherlands)
11.00 - 11.30 Coffee Break
11.30 - 12.00 Molecular archeology from next generation explorations
F. Demichelis (Trento, Italy)
17.00 - 17.20 Immuno oncology as a new modality of cancer treatment: research and
development
R. Canetta (BMS, Wallingford, USA)
17.20 - 17.50 Coffee Break
THE CLINICIANS’ VIEW – Joint Meeting SIC-AIOM
12.00 - 12.30 Detection of genetic and epigenetic alterations in plasma circulating tumor DNA
F. Di Nicolantonio (Turin, Italy)
17.50 - 18.10 Targeted drugs for melanoma
P. Ascierto (Naples, Italy)
12.30 - 13.00 Selected presentations
18.10 - 18.30 Targeted drugs for colon carcinoma
S. Siena (Milan, Italy)
13.00 - 14.00 Lunch
18.30 - 18.50
Combined immuno and chemotherapeutic strategies
G. Parmiani (Milan, Italy) Sponsored by EACR
18.50 - 19.10 Applications of OMIC approaches to cancer
F. Marincola (Bethesda, USA)
19.20 - 20.20 MEETING OF SIC YOUNG INVESTIGATORS
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7
55 Annual Meeting
th
of the
Italian Cancer Society
Wednesday 25 September
SCIENTIFIC PROGRAMME
VENUE: VILLAGGIO GUGLIELMO
Thursday 26 September
SCIENTIFIC PROGRAMME
VENUE: VILLAGGIO GUGLIELMO
:
understanding onc-OMICS
for patient-tailored cancer therapy
Catanzaro
23 – 26 September 2013
8.00 ‐ 9.00
8.15 ‐ 12.30
ANIMAL MODELS OF CANCER
8.15 - 8.45
Title to be defined
E. Holland (New York, USA)
8.45 - 9.15
Circulating metastasis-initiating cells in breast cancer
A. Trumpp (Heidelberg, Germany)
9.15 - 9.45
10.20 ‐ 11.20 GIORGIO PRODI LECTURE
From RET oncogene identification in thyroid cancer to targeted therapy
M. Santoro (Naples, Italy)
The role of hypoxic responses in leukemogenesis
R. Bernardi (Milan, Italy)
9.45 - 10.15
Novel players in tumor microenvironment
U. Cavallaro (Milan, Italy)
11.20 ‐ 13.20 POSTER VIEWING
10.15 - 10.45 Coffee Break
13.20 - 14.20 Lunch
10.45 - 11.15 Application of genomics to zebrafish models in cancer research
M.A. Rubin (New York, USA)
9.00 ‐ 10.20
MEET‐THE‐EXPERT: INFORMAL ROUND‐TABLE@BREAKFAST
Parallel Sessions
Cancer Genomics A. Iavarone (New York, USA) - M.A. Rubin (New York, USA)
Non‐Coding RNAs F.J. Slack (New Haven, USA )
Oncometabolics
P. Chiarugi (Florence, Italy)
POSTER DISCUSSION 1: Parallel Sessions
Poster Discussion A
Poster Discussion B
14.20 ‐ 15.40 POSTER DISCUSSION 2: Parallel Sessions
Poster Discussion A
Poster Discussion B
11.15 - 11.45 Zebrafish models of cancer
M.C. Mione (Eggenstein-Leopoldshafen, Germany)
15.45 ‐ 18.15 CANCER STEM CELLS
11.45 - 12.15 Selected presentations
15.45 - 16.15 The importance of asymmetry for gene expression in the stem cell
compartment of human prostate epithelium
N.J. Maitland (York, United Kingdom) Sponsored by EACR
12.30 ‐ 13.30 CLOSING LECTURE
J. Quackenbush (Boston, USA)
16.15 - 16.45 Stem cells in homeostasis and cancer: the good, the bad and the ugly
R. Fodde (Rotterdam, The Netherlands)
13.45 ‐ 14.00 CLOSING REMARKS
16.45 - 17.15 Clinical implications of cancer stem cell hypothesis
L. Ricci-Vitiani (Rome, Italy)
13.30 ‐ 13.45 AWARD FOR THE BEST ORAL SELECTED PRESENTATION
14.00 - 15.00 Lunch
17.15 - 17.45 Modeling of human leukemias
J.J. Schuringa (Groningen, The Netherlands)
17.45 - 18.15 Selected presentations
18.15 ‐ 19.00 AWARD CEREMONY
19.00 ‐ 20.00 SIC GENERAL ASSEMBLY
20.30
SOCIAL DINNER
8
9
55 Annual Meeting
Scientific Information
th
of the
Italian Cancer Society
Scientific Information
:
understanding onc-OMICS
for patient-tailored cancer therapy
Catanzaro
23 – 26 September 2013
CME Credits
The scientific programme of the 55 th Annual Meeting of the Italian Cancer Society has been submitted
for the accreditation by the Italian Ministry of Health. Credits have been requested for the following
categories:
- Medical Surgeon (Haematology, Medical Genetics, Oncology, Pathological Anatomy, Pharmacology
and Clinical Toxicology, Clinical Pathology, Internal Medicine)
- Biologist, Pharmacist, Chemist (Analytical Chemistry), Physicist (Health Physics), Veterinary Surgeon
Abstract submission
The organizers invite authors to submit abstracts for consideration and inclusion in the programme.
Abstracts must be sent by June 7 2013 and must focus on the following topics:
• Autophagy, apoptosis, necrosis
and senescence
• Cancer genetic
• Cancer modeling and imaging
• Cancer stem cells
• Cell adhesion, migration,
invasion and metastasis
• Innovative therapeutic
• Molecular epidemiology
and chemoprevention
• Molecular markers of diagnosis,
prognosis and response to therapy
• Animal models of cancer
• Nanotechnology
• Cell metabolism and cell cycle
regulation
• Signal transduction
and intracellular trafficking
• Control of gene expression
and epigenetics
• System biology
and emerging technologies
• DNA damage and molecular
responses to damage
• Targeted therapy
• Drug resistance
• Infectious agents and cancer
• Tumor immunology and immunotherapy
• Tumor microenvironment:
inflammation, hypoxia and angiogenesis
Abstracts must be written in English and must not exceed 2.500 characters (including blanks).
All submitted abstracts will be reviewed by a Scientific Committee and selected for oral or poster
presentations (sizes: cm 70x100h.).
PRIZES
“Piero Trivella” and “EACR” Prizes to the best posters
The Associazione Oncologica Pisana “Prof. Piero Trivella” and the European Association for Cancer
Research (EACR) will award the best posters.
To apply for poster prizes it is necessary to:
• Be SIC Member
• Be first author of the submitted abstract (copy of the abstract must be attached)
• Be younger than 35 years at the date of the Meeting (copy of the identity card must be attached)
• Be regularly registered in the Meeting
Those who wish to apply for the prize must present their poster at the Meeting even in case their
abstract has been selected as oral presentation. Should the winner not be present at the Award
Ceremony, the prize will be awarded following the ranking order.
The application must be sent by June 14, 2013.
Travel Grants
A limited number of Travel Grants can be awarded upon financial availability.
To apply for Travel Grants it is necessary to:
• Be SIC Member
• Be first author of the submitted abstract (copy of the abstract must be attached)
• Be younger than 35 years at the date of the Meeting (copy of the identity card must be attached)
• Be regularly registered in the Meeting
• Attach the Curriculum Vitae including a list of all publications
The application must be sent by June 14, 2013.
“Elena Cappannini” Prize to the best 2012 publication as first author in innovative
approaches for cancer treatments
To apply for this prize in memory of Elena Cappannini it is necessary to:
• Be first author of the publication in the field of preclinical or clinical innovative approaches for
cancer treatment published in 2012 (copy of the paper and CV must be attached)
• Be younger than 40 years at the date of the Meeting (copy of the identity card must be attached)
The application must be sent by June 14, 2013.
All applications are available on the SIC website and must be sent to the SIC Secretariat via
e-mail: [email protected]
All prizes will be awarded, on the basis of a merit ranking, on September 25, during the
Award Ceremony.
Abstracts must be sent using the online form. Abstracts sent in any other way will not be accepted.
Notification of acceptance or rejection, together with information about session, date, time and type
of presentation, will follow.
Each Author can present only one abstract. Abstracts will be included in the Programme and in
the Abstract book only if the Presenting Author will be regularly registered in the Congress.
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11
55 Annual Meeting
General Information
th
of the
Italian Cancer Society
Registration Information
:
understanding onc-OMICS
for patient-tailored cancer therapy
Catanzaro
23 – 26 September 2013
Dates
Catanzaro, 23 – 26, September 2013
Registration Fees
Congress Venue
September 23
Università degli Studi “Magna Græcia” di Catanzaro
Viale Europa
88100 Germaneto – Catanzaro
September 24-26
Villaggio Guglielmo Congress Center
Piazza Susanna, 1
88069 Copanello - Catanzaro
www.villaggioguglielmo.it
SIC MEMBER (*)
NON SIC MEMBER (**)
SIC MEMBER UNDER 35 (*)
NON SIC MEMBER UNDER 35 (**)
Early registration
by July 7
€ 355,00
€ 455,00
€ 210,00
€ 270,00
Late registration
by September 9
€ 410,00
€ 510,00
€ 260,00
€ 330,00
on-site registration
€ 450,00
€ 550,00
€ 280,00
€ 355,00
(*)VAT non applicable as for law ex Art.4 DPR 633/72; (**) VAT 21% included
The VAT rate will be applied depending on the Italian fiscal law at the time of payment.
SIC Secretariat
Società Italiana di Cancerologia
Via G. Venezian, 1 – 20133 Milan
Ph. +39 02 2666895 – Fax +39 02 2664342
Email: [email protected] – Web site: www.cancerologia.it
Registration fees include:
• admission to the scientific sessions
• admission to the exhibition area
• name badge and congress kit
• abstracts book
• attendance certificate
• ECM certificate
• welcome cocktail, coffee breaks, light lunches and social dinner
Registrations can be requested submitting the registration form online. Participants can also download
a PDF file, fill it in and send it by mail or fax to the Organizing Secretariat AdriaCongrex
E-mail: [email protected]; Fax +39 0541 305842
Organizing Secretariat
Adria Congrex Srl
Via Sassonia, 30 – 47922 Rimini RN
Ph. +39 0541 305811 - Fax +39 0541 305842
E-mail: [email protected] – Web site: www.adriacongrex.it/sic2013
Registrations without payment will not be accepted.
Language
The official language of the Meeting is English. Simultaneous translation will not be provided.
Payment Methods and Details
Payment should be made by one of the following methods:
Badges
Participants are kindly requested to wear their badge throughout the Meeting.
Bank transfer
Please transfer the payment to Adria Congrex
Bank details: IT 18 N 06285 24214 CC0142118559
The payment transfer form should clearly state “SIC 2013 – Code 1130312VACH and the name(s) of
the delegate(s).
Certificates of Attendance
Certificate of attendance is issued on request to all registered participants at the end of the Meeting.
Exhibition and Sponsorship
A technical, pharmaceutical and publication exhibition will take place in the Meeting Venue throughout
the scientific works. Additional sponsoring opportunities are available. For any information, please
contact the Organizing Secretariat Adria Congrex.
Credit card
All major credit cards are accepted (American Express, VISA, Mastercard, Cartasi).
REGISTRATIONS WILL BE PROCESSED ONLY WHEN ACCOMPANIED BY THE TOTAL PAYMENT.
Cancellation
In case of cancellation reimbursement will not be done.
12
13
55 Annual Meeting
Registration Information
th
of the
Italian Cancer Society
Registration Information
:
understanding onc-OMICS
for patient-tailored cancer therapy
Catanzaro
23 – 26 September 2013
Insurance
Registration fee does not include insurance of any kind. The Congress Organizers will not be responsible
for any participant failing or damages. Any type of insurance should be purchased by congress
participants on their own.
Official housing bureau and travel agency
For information and/or reservation please contact the Official Housing Bureau and Travel Agency
of the Meeting: Via Sassonia, 30 - 47922 Rimini - Ph. +39 0541 305898 - Fax +39 0541 305842
E-mail: [email protected]
The Organizing Secretariat provides rooms at the conference venue,Villaggio Guglielmo.
Reservations can be requested submitting the online registration form available on the website
www.adriacongrex.it/sic2013.
Reservations must be sent by September 3, 2013. After this deadline rates and availability will not be
guaranteed. Rooms will be allocated on a first come first served basis. Hotel rates are intended per
person, per day and include vat (city tax not included).
Reservations can be requested submitting the hotel accommodation form online or downloading the
PDF form, (in this case, the PDF form can be sent by mail or fax to the Organizing Secretariat, Adria
Congrex, E-mail [email protected]; Fax +39 0541 305842).
Reservations without deposit will not be processed
Hotel Accommodation at Villaggio Guglielmo
Treatment
Dus - Double use for single use
Half Board with dinner
78,00
B&B
65,00
Twin Room
60,00
50,00
Three bed in a Room
54,00
45,00
Special Packages (transfer service included)
A) Double use for single use: euro 228,00
B) Twin room/Double room: euro 180,00 per person
C) Three bed room: euro 164,00 per person
The special Packages include:
- n. 2 overnights on Bed&Breakfast treatment at Villaggio Guglielmo
(on Sept 23rd and Sept 25th, 2013)
- n. 1 overnight on Half Board treatment at Villaggio Guglielmo (on Sept 24th, 2013)
- transfer from Lamezia Terme** (airport or railway station) on Sept 23rd, 2013
- transfer from Villaggio Guglielmo to Lamezia Terme** (airport or railway station) on Sept 26th
- vat
**Lamezia Terme is 50 Km far from Villaggio Guglielmo.
City Tax: euro 2,00 per person, per day. City tax will be paid directly to the hotel at the check out.
Transfer service
People who don’t book special packages, can require the transfer from Lamezia Terme airport or railway
station and viceversa, sending an email to railways and viceversa, sending an email to booking@adriacongrex.
it writing all the details (date, timetable, number of person).
14
15
55
th
:
understanding onc-OMICS
for patient-tailored cancer therapy
Catanzaro
23 – 26 September 2013
IMPORTANT DATES
Deadline for abstract submission
June 7, 2013
Deadline for application for
“Piero Trivella” and “EACR” Prizes to the best posters
June 14, 2013
Deadline for application for Travel Grants
June 14, 2013
Deadline for application for
the Prize “Elena Cappannini”
June 14, 2013
Deadline for early registration fees
July 7, 2013
Deadline for hotel accommodation
September 3, 2013
Deadline for late registration fees
September 9, 2013
For abstracts submission, registrations and hotel accommodation
please visit
www.adriacongrex.it/sic2013