saveJANSSEN:Layout 1 9-04-2014 17:17 Pagina 1 save the date 13:15-14:15 Italian Conference on AIDS and Retroviruses ROMA, 25-27 MAGGIO 2014 SHERATON CONFERENCE CENTER Lunedì 26 PI and PI in the Moderatore: A. Antinorimanagement (Roma) of infectious diseases Unrestricted educational grant di Speakers: H. Hinrichsen (Kiel, D), A.L. Pozniak (London, UK) Discussants: A. d’Arminio Monforte (Milan, I), M. Galli (Milan, I) maggio 2014 Sito web del Congresso ICAR www.icar2014.it EXPERT MEETING Provider e Segreteria Organizzativa Effetti Srl Via Gallarate, 106 - 20151 Milano Ref. Barbara Bocciardi Tel. 02 3343281 - Fax 02 33496370 E-mail: [email protected] www.effetti.it ICAR VI CONGRESSO NAZIONALE saveJANSSEN:Layout 1 9-04-2014 17:17 Pagina 3 Gentile Dottoressa, Egregio Dottore, Scientific Programme La partecipazione alla sessione è a numero chiuso e riservata agli Specialisti iscritti al Congresso. La preghiamo pertanto di ritornarci compilata la scheda di adesione allegata per la conferma dell’iscrizione. PI and PI in the management of infectious diseases RingraziandoLa anticipatamente, Le porgiamo i più cordiali saluti. Il Provider Effetti Srl Faculty EXPERT MEETING Antonella d’Arminio Monforte San Paolo Hospital, University of Milan, I Massimo Galli Luigi Sacco Hospital, University of Milan, I Holger Hinrichsen Gastroenterologisch-Hepatologisches Zentrum, Kiel, D Anton Louis Pozniak Chelsea and Westminster Hospital – NHS Foundation Trust, London UK Moderatore: A. Antinori (Roma) VI CONGRESSO NAZIONALE ICAR Italian Conference on AIDS and Retroviruses save the date save the date Lunedì 26 Protease inhibitors can be considered the “core” agents of both HIV and HCV therapy, actually the most common infectious diseases impacting on patients’ life and in clinical practice for their comorbidities burden. In HIV, DRV is the third agent allowing a real tailored therapy for its important successful data obtained in association with other various “companion” drugs. In fact, it has not only shown its efficacy in monotherapy RCTs but it has proved to be an ideal third agent, superior to PI competitors, in triple therapy (with ABC/3TC or TDF/FTC) as well as in dual therapy strategies (with RAL, MVC, ETR, 3TC) and also in the ongoing studies with RPV and, more recently, with DTG (NEAT Study). In hepatitis C, moving from settled efficacy data in real world practice obtained by telaprevir (or BOC) + PR, which contributed to confirm its role as SOC, we will focus on second generation PI, simeprevir, in terms of superior efficacy and safety profile. SIM, the first new PI to be marketed in hepatitis C therapy, has shown efficacy and safety data in HCV1 and HCV4 with PR and, in combination with SOF, in HCV naïve F3 and F4 and NR F0-F4 (COSMO Study) and in phase II study in combination with DCV. Looking to recent pipelines, HCV protease inhibitors can be defined as the “sine qua non” agents in HCV therapy. Discussants: A. d’Arminio Monforte (Milan, I), M. Galli (Milan, I) 13.15-13.45 Which strategies in HIV? A.L. Pozniak (London, UK) 13.45-14.15 Which strategies in HCV? H. Hinrichsen (Kiel, D) maggio 2014 Abbiamo il piacere di invitarLa a partecipare all’EXPERT MEETING “PI and PI in the management of infectious diseases” che si terrà lunedì 26 maggio 2014 dalle ore 13.15 alle ore 14.15, organizzato nell’ambito del 6° Congresso ICAR.