Dottorato di Ricerca in BIOMEDICINA E NEUROSCIENZE (PhD Course in Biomedicine and Neuroscience) Coordinatore: Prof. Giovanni Zummo Sede Amministrativa: Dipartimento di Biomedicina Sperimentale e Neuroscienze Cliniche (BIONEC) AVVISO DI SEMINARIO Mercoledì 4 luglio 2012, ore 15:30 Aula “E. Nesci”, Sezione di Anatomia Umana Dipartimento BIONEC Prof. Massimo Cocchi* Full Professor of Nutrition Biochemistry Faculty of Human Sciences Institute "Paolo Sotgiu" of Quantitative and Quantum Psychiatry and Cardiology L.U.de.S. University, Lugano, Switzerland I segnali psichiatrici e cardiologici scritti nelle piastrine Abstract In our study we have evaluated the theme of the platelet fatty acid composition in subjects with a clinical diagnosis of Major Depression (MD), in subjects with a clinical diagnosis of Ischemic Heart Disease (IHD) according to the coronary angiography and in control subjects. We have analyzed all the groups without taking in account therapies, gender and age. As far as we know, the platelet fatty acid composition has never been analyzed before, in MD. The results obtained with the Self Organizing Map (SOM) show the evidence of three fatty acids, Arachidonic Acid (AA), Linoleic Acid (LA), and Palmitic Acid (PA) in a peculiar position with respect to the biochemical characterization of MD and three fatty acids, Arachidonic Acid (AA), Linoleic Acid (LA) and Oleic Acid (OA) in a peculiar position with respect to the biochemical characterization of the IHD. Bio molecular considerations are made about the possibility of controlling positive changes in platelet viscosity, in both pathologies. th *: Massimo Cocchi was born in Bologna on 8 October 1945. He graduated in Medicine and Surgery in 1971 at the University of Bologna. In 1990 he has been appointed as honorary lecturer of Nutrition Biochemistry (Scottish Agricultural College). He has been appointed as Professor of Nutrition Biochemistry of the Scottish Agricultural College (1995-1998). In 1998 he received the title of Professor in Perpetuity of the Scottish Agricultural College. In 1999 he has founded the scientific journal “Progress in Nutrition” (Impact Factor since 2009). He has been elected President of the Scientific Association “ARNA”, Associazione Ricercatori Nutrizione e Alimenti (2003–2009). In 2005 he has been appointed as Contract Professor of Food and Human Nutrition at the Faculty of Veterinary Medicine of the University of Bologna today changed in Nutrition Biochemistry. In 2008 he has been appointed as Full Professor of Nutrition Biochemistry at the L.U.de.S. University, Lugano, Switzerland. In 2005 he has been appointed as President of the Italian Society of Experimental Biology, Section of Bologna “Oliviero Mario Olivo”. In 2005 he started, with Lucio Tonello, to study the platelet fatty acids in groups of patients (Depressive and Ischemic) realizing a combination between Biochemistry and Artificial Neural Network which has allowed to identify the depressive and the ischemic population against the apparently normal people. On the argument many papers, meetings and conferences have been hold. In 2008, Kioto Prize nomination. PROF. GIOVANNI ZUMMO, SEZIONE DI ANATOMIA UMANA “EMERICO LUNA” DIPARTIMENTO DI BIOMEDICINA SPERIMENTALE E NEUROSCIENZE CLINICHE, UNIVERSITÀ DEGLI STUDI DI PALERMO Via del Vespro, 129 – 90127 Palermo - Tel 091.6553508 – Fax 091.6553580 – e-mail: [email protected]