LINEE GUIDA PER IL RINFORZO DELLE SUTURE IN CHIRURGIA BARIATRICA Leakage/fistole e sanguinamento dalle linee di sutura: siti ed incidenza Luigi Angrisani Director - General and Endoscopic Surgery Unit S.Giovanni Bosco Hospital, Naples, Italy “S.GIOVANNI BOSCO” EXPERIENCE N=1109 Pts 148 160 140 120 120 106 100 74 80 56 60 40 20 33 20 19 12 0 0 28 27 39 28 1 4 69 62 36 31 6 21 3 18 3 68 15 9 67 19 37 6 15 6 25 18 37 0 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 Gastric Banding Gastric Bypass Sleeve Gastrectomy Angrisani 2013 Leak is reported in 1-7 % of patients Leak rate 1.5% (75% GE junction) Prevention 1) Not too tight sleeve (using larger bougies ≥ 40fr)* 2) Firing the stapler lateral to the angle of His 3) Performing an intraoperative leak test * * Conclusions • Mean leak rate 2.4% (range 0-7%) • 92% at the GE junction • 79% of leaks occurred more than 10 days postoperatively • Super-obese pts leak rate 2.9% vs morbid obese patients leak rate 2.2% (not significant p>0.05) • Stricture rate: 0.5% • Bleeding rate: 0.7% • Boogie size of <40Fr is associated with increased risk of leak • Oversewing or buttressing of the staple line does not have a clinically significant effect on leaks Aurora A et al. Surg Endosc (2012) 26:1509-1515) Techniques used for LSG Effect of technique on leak rate Overall leak rate: 2.2% Conclusions 1) Leak rate of approximately 2.4% 2) Clinically significant bleeding and stricture rate of less than 1% 3) Leak at GE junction 89% 4) Greater risk of leak in BMI > 50 kg/m2 5) Greater risk of leak with smaller bougies (<40 Fr) 6) Oversewing or buttressing of the staple line does not have a clinically significant effect on leak ANTI -OBESITY PROCEDURES n= 1932 Jan 1996 - Dec 2012 100 495 326 510 24 459 Lap Band System® Bioenterics Intragastric Balloon® Sleeve Gastrectomy Gastric Bypass BPD-Duodenal Switch Revisions ANGRISANI 2013 Naples, Italy RESULTS Complications: intraoperative leaks in SG pts N=2/495 (0,4%) Intra-Operative conversion to: 1 pt* 1pt Roux en Y limb Roux-en-Y GBP with with Sub-Total Gastrectomy Distal Stomach Preservation * Band removal 1 year before ANGRISANI 2013 Naples, Italy Leak rate: 17/1133 (1.5%) p value: not statistically significant Laparoscopic Roux en Y Gastric Bypass N=510 (Jan 2000 – Dec 2012) •Mortality 1 (0,2%) •Laparotomic Conversion 4 (0.8%) •Gastro-jejunal Leak 2 (0,4%) •Gastro-jejunal Stenosis 3 (0,6%) •Mean Operative Time 140 25 min •Hospital Stay 5 2 days General and Endoscopic Surgery Unit “S. Giovanni Bosco” Hospital - Naples - Italy Director: Luigi Angrisani Laparoscopic Roux en Y Gastric Bypass REOPERATIONS 22/510 (4.3%) Jan 00- Dec 12 Internal hernia Bowel perforation Jejuno-jejunostomy stenosis Bowel obstruction / Adhesions Intussusception Hemoperitoneum Protein malnutrition N=11 N=3 N=2 N=2 N=2 N=1 N=1 General and Endoscopic Surgery Unit “S. Giovanni Bosco” Hospital - Naples - Italy Director: Luigi Angrisani CONCLUSIONS The healing time of a SG leak is longer than GBPs’ leak Even if the rate of complications of GBP & SG is similar, those after SG appear to have a worse outcome leading to more aggressive procedures (Total/distal gastrectomy) Revisional procedures have an increased risk of leak versus primary procedures. Angrisani-Formisano 2013