Nanoparticelle in biomedicina: terapia
Nanostrutture autoassemblate per la veicolazione di
molecole farmacologicamente e biologicamente attive
Supramolecular engineering for drug delivery
Bio-compatible organic and inorganic carriers:
different internal sizes & functionalisations
zeolites: sub-nm range
mesoporous silica: up to 15 nm
amylose: adaptive helical conformation
cyclodextrines: molecular caging
Vast range of guest molecules
squaraines
carotenoids
porphyrins
suitable drugs
carotenoids
porphyrins
squaraines
Milano – 17 ottobre
Applicazioni mediche delle Nanotecnologie
Nanoparticelle in biomedicina: terapia
Nanostrutture autoassemblate per la veicolazione di
molecole farmacologicamente e biologicamente attive
Applications & advantages
full bio-compatibility
solubility in aqueous media
(even for oxide matrices)
drug delivery
photodynamic therapy (PDT)
high loading of active molecules
aggregation prevented
drugs for PDT: no need of releasing
Examples of self-assembled nanostructures
zeolite / squaraine
cyclodextrin / carotenoid
Milano – 17 ottobre
amylose / squaraine
Applicazioni mediche delle Nanotecnologie