PANCREATITE ACUTA: C’E’ SPAZIO PER TRATTAMENTI LAPAROSCOPICI ? M.FILAURO S.C. CHIRURGIA GENERALE ED EPATOBILIOPANCREATICA E.O.OSPEDALE GALLIERA GENOVA Sestri Levante, 20 gennaio 2007 INDICAZIONI ALLA VDL NELLA P.A. STADIAZIONE NO!! ( TAC) TRATTAMENTO DELLE COMPLICANZE TRATTAMENTO DELLE CAUSE SI SI TRATTAMENTO VDL NELLE COMPLICANZE DELLA P.A. SEVERA NECROSI INFETTA SI PSEUDOCISTI EMORRAGIE NO PERFORAZIONI VISCERALI TRATTAMENTO VDL DELLE CAUSE DELLA P.A. LITIASI BILIARE LITIASI PANCREATICA SI ( VLC + ERC INTRAOP + PST) NO MALFORMAZIONI BILIOPANCREATICHE TRAUMI PANCREATICI NO SI ( SOLO DRENAGGIO) APPROCCIO VDL NEL TRATTAMENTO DELLE NECROSI INFETTE TRANSPERITONEALE RETROPERITONEALE TRANSGASTRICO TRANS- FISTOLA DA DRENAGGIO ( PERCUTANEO/CHIRURGICO) APPROCCIO VDL TRANSPERITONEALE OTTICA 30° 4/5 ACCESSI PINZE ATRAUMATICHE SISTEMA PER LAVAGGIO/ASPIRAZIONE ADEGUATO LA TATTICA VDL RIPRODUCE L’APPROCCIO OPEN: ESPLORAZIONE PERITONEALE LAVAGGIO DELLE RACCOLTE PARACOLICHE E SUBFRENICHE APERTURA DELLA RETROCAVITA’ TRAMITE IL LEG.GASTROCOLICO ASPIRAZIONE/ ASPORTAZIONE DEL MATERIALE NECROTICO INFETTO LAVAGGI DELLA RETROCAVITA’ DRENAGGI MULTIPLI Laparoscopic assisted pancreatic necrosectomy: a new surgical option for treatment of severe necrotizing pancreatitis. Parekh D. Arch Surg 2006, 141 (9):895-902 19 pazienti con PA severa sottoposti a necrosectomia transperitoneale con HALS ( hand assisted laparoscopic surgery) 18/19 pazienti con procedura completata 2 HALS 4 reinterventi 2 open “ Pancreatic debridment with HALS may provide a new option for the Surgical treatment of selected patients with severe necrotizing Pancreatitis.” Retroperitoneal endoscopic debridement for infected peripancreatic necrosis. Seifert H, et al. Lancet. 2000 Aug 19;356(9230):653-5 Standard management of infected peripancreatic necrosis consists of open surgical debridement and lavage--a traumatic intervention with substantial morbidity and mortality. As an alternative and novel approach with minimum invasiveness, we present fenestration of the gastric wall and debridement of infected necrosis by direct retroperitoneal endoscopy. In three patients, this strategy led to rapid clinical improvement and no serious complications. Transgastric endoscopic therapy may be a less traumatic alternative to surgery and should be further assessed in prospective studies. LE INDICAZIONI, IL TIMING E LA TATTICA IN CASO DI P.A. NON SONO MODIFICATE DALLA VDL. LA VDL COSTITUISCE UNA METODICA DI ACCESSO ALLA CAVITA’PERITONEALE ED AL RETROPERITONEO MINIINVASIVA , CON I VANTAGGI PROPRI DI TALI APPROCCI. LA RETROPERITONEOSCOPIA AVREBBE IL VANTAGGIO DI CONSENTIRE UNA TOILETTE PIU’ MIRATA E RISPETTOSA DELLE STRUTTURE VISCERALI, E DI POTERE ESSERE RIPETUTA ( ANCHE SULLA GUIDA DI DRENAGGI LASCIATI IN SITU). Direct retroperitoneal approach to necrosis in severe acute pancreatitis. Fagniez PL Br J Surg. 1989 Mar;76(3):264-7 From 1981 to 1987, 40 patients with severe acute pancreatitis were operated on using a direct retroperitoneal approach, 22 primarily and 18 after a first operation performed through another incision. The retroperitoneal approach consisted of a left lateral incision, just anterior to the 12th rib, allowing direct access to the pancreas and a complete manual exploration of the gland and peripancreatic spaces. The direct retroperitoneal approach permits the removal of necrosis and several reoperations without the risk of large wound dehiscence and does not preclude the extension of the incision to a subcostal incision when necessary. APPROCCIO VDL AL TRATTAMENTO DELLE RACCOLTE PERIPANCREATICHE E DELLE PSEUDOCISTI. RACCOLTA LIQUIDA PERIPANCREATICA SINTOMATICA: EVACUAZIONE E DRENAGGIO PSEUDOCISTI : DRENAGGIO DERIVAZIONE INTERNA ( PSEUDOCISTODIGIUNOANASTOMOSI) “Minimally invasive procedures, including percutaneous drainage, endoscopic drainage or minimally invasive surgery ( i.e, retroperitoneo-scopy) for infected pancreatic necrosis may play a role as a temporary measure to bridge the critical early time after onset of acute pancreatitis to a later optimal time point for definitive intervention. Otherwise, they should be limited to specific indications in patients who are critically ill and unfit for conventional surgery or clinical trials” J Werner, S Feurbach,W Uhl and M Buchler GUT, 2005;54:426-436 “Newer approach such as laparoscopic, endoscopic or retroperitoneal procedures might decrease morbidity and mortality in patients with severe AP”. S.Heinrich,M Schafer,V. Rousson, PA Clavien Evidence-based treatment of acute pancreatitis: a look to established paradigms. Annals Surg 2006; 243(2):154-168.