V INTERNATIONAL MEETING
NUCLEAR CARDIOLOGY TODAY-2004
The State of the Clinical Practice and
Future Molecular Directions
S. Agostino, De Civitate Dei
(Codice XV sec.) Biblioteca Malatestiana- Cesena
Teatro Comunale “A.Bonci”
CESENA - ITALY
June 10-11-12, 2004
Final Program - Call for Abstracts
www.ausl-cesena.emr.it/NuclearCardiologyToday
VENUE OF THE MEETING
CESENA - Teatro Comunale “A. Bonci”
CESENA - Teatro Comunale (interior)
V INTERNATIONAL MEETING
NUCLEAR CARDIOLOGY TODAY-2004
The State of the Clinical Practice and
Future Molecular Directions
AMERICAN SOCIETY OF
NUCLEAR CARDIOLOGY
EUROPEAN ASSOCIATION
OF NUCLEAR MEDICINE
ASSOCIAZIONE ITALIANA
DI MEDICINA NUCLEARE
ed Imaging Molecolare
in collaboration with
WORKING GROUP
ON NUCLEAR CARDIOLOGY
EUROPEAN SOCIETY OF CARDIOLOGY
ASSOCIAZIONE NAZIONALE
CARDIOLOGI EXTRAOSPEDALIERI
SOCIETA’ ITALIANA CARDIOLOGIA
OSPEDALITA’ ACCREDITATA
ASSOCIAZIONE NAZIONALE
MEDICI CARDIOLOGI
OSPEDALIERI
SOCIETA’
ITALIANA
DI CARDIOLOGIA
GRUPPO ITALIANO
DI CARDIOLOGIA
NUCLEARE
ASSOCIAZIONI
REGIONALI
CARDIOLOGI
AMBULATORIALI
The Nuclear Cardiology Today Meeting has reached its Vth edition.
This International Meeting attracts attendees from Europe and beyond and its
goal is not only to update about the "state of the art", but also to present new
applications of Nuclear Cardiology in order to move the field forward.
New potential applications will be discussed like "Molecular Nuclear Cardiology",
"Receptors imaging", "Assessment of gene therapy", "Neo angiogenesis" etc.
The Meeting is directed towards Cardiologists, Nuclear Medicine Physicians,
Internal Medicine Physicians and Physicists. The Faculty will include many
of the major experts of the field. The Meeting will be held in Cesena (EmiliaRomagna, Italy). We anticipate that this Meeting will continue to be of interest
to the International Community and encourage your attendance.
Please visit our web site for more information:
www.ausl-cesena.emr.it/NuclearCardiologyToday
Jeffrey Leppo Pier Luigi Pieri Barry Zaret
Co-Directors
Scientific Secretariat:
Pier Luigi Pieri, MD
Chief, Department of Medicina Specialistica
Chief, Division of Cardiovascular Medicine
Director Nuclear Cardiology
"M. Bufalini Hospital"
V.le Ghirotti, 286 - 47023 Cesena - Italy
e-mail: [email protected]
Tel: (+39) - 0547 352860 Fax: (+39) - 0547 304010
Organizing Secretariat:
“Cesena Congress”
Via Isei, 79 - 47023 Cesena - Italy
e-mail: [email protected]
Tel. + Fax: (+39) - 0547 20425
Organized by:
Nuclear Cardiology Unit
In collaboration with:
- Division Cardiovascular Medicine
- Nuclear Medicine Division
- "M. Bufalini - G. Marconi - P. Angioloni" Hospital
- Azienda USL Cesena - Italy
Under the Auspices of:
- American Society of Nuclear Cardiology (A.S.N.C.)
- European Association of Nuclear Medicine (E.A.N.M.)
- Associazione Nazionale Medici Cardiologi Ospedalieri (A.N.M.C.O.)
- Associazione Italiana Medicina Nucleare (A.I.M.N.)
- Società Italiana di Cardiologia (S.I.C.)
- Associazione Nazionale Cardiologi Extra-ospedalieri (A.N.C.E.)
- in collaboration with Working Group on Nuclear Cardiology of European Society of Cardiology
- Gruppo Italiano di Cardiologia Nucleare (G.I.C.N.)
- Associazioni Regionali Cardiologi Ambulatoriali (ARCA)
- Società Italiana Cardiologia Ospedalità Accreditata (SICOA)
- Regione Emilia-Romagna
- Comune di Cesena
- Azienda USL di Cesena
Honor Commitee
Giovanni Bissoni
Robert C. Hendel
Health Councilman
Regione Emilia-Romagna
President A.S.N.C.
Giordano Conti
President E.A.N.M.
Mayor of Cesena
Maria Basenghi
General Director AUSL Cesena
Michele Sanza
Health Director AUSL Cesena
Frans Corstens
Alessandro Boccanelli
President A.N.M.C.O.
Emilio Bombardieri
President A.I.M.N.
Maurizio D. Guazzi
President S.I.C.
Francesco Perticone
President A.N.C.E.
Giovanni Zito
President A.R.C.A.
Cesare Proto
President S.I.C.O.A.
Honorary President
H. William Strauss
President
Pier Luigi Pieri
Jeffrey Leppo
Jeffrey Leppo
Co-Directors
Pier Luigi Pieri
Barry Zaret
Scientific Committee
Jagat Narula Pier Luigi Pieri H. William Strauss
Barry Zaret
Organizing Committee
Pier Luigi Pieri (President)
M. Agostini
Host Committee
R. Antonini F. Del Dottore D. Baccos
G. Moscatelli G. Sarti
P. Ghezzi
FACULTY
J. Bax (Leiden - The Nederland)
G. Bisi (Torino)
R. Belardinelli (Ancona)
G. Beller (Charlottesville - USA)
I. Carriò (Barcelona - Spain)
M. Chiariello (Napoli)
M. Comaschi (Genova)
G. Condorelli (Roma)
A. Cuocolo (Napoli)
I. Dalle Mule (Pieve di Cadore)
G. Di Pasquale (Bologna)
T. El Kadi (Cairo - Egypt)
A. Galassi (Catania)
M. Galli (Livorno)
E. Garcia (Atlanta - USA)
A. Giordano (Roma)
R. Giubbini (Brescia)
R. Hendel (Chicago - USA)
E. Inglese (Novara)
A. Iskandrian (Birmingham - USA)
A. Lahiri (London - UK)
J. Leppo (Pittsfield - USA)
C. Marcassa (Veruno)
P. Marzullo (Pisa)
A. Maseri (Milano)
M. Mazzanti (Ancona)
G.F. Mazzotta (Genova)
J. Mieres (New York - USA)
F. Miglio (Bologna)
E. Milan (Castelfranco Veneto)
M. G. Modena (Modena)
J. Narula (Irvine - USA)
0. Parodi (Milano)
P. Perrone-Filardi (Napoli)
P.L. Pieri (Cesena)
M. Salvatore (Napoli)
G.M. Sambuceti (Pisa)
O. Schillaci (Roma)
M. Schwaiger (Munchen - Germany)
R. Sciagrà (Firenze)
H.W. Strauss (New York - USA)
F. Tartagni (Cesena)
M. Timio (Foligno)
J. Udelson (Boston - USA)
T. Varetto (Torino)
F.J.Th. Wackers (New Haven - USA)
T. Yasuda (Boston - USA)
P.L. Zanco (Vicenza)
B. Zaret (New Haven - USA)
8:00
Registration
8.30
OPENING REMARKS
P.L. Pieri (President of the meeting)
H. W. Strauss (Honorary President)
R. Hendel (President A.S.N.C.)
F. Corstens (President E.A.N.M.)
G. Di Pasquale (President Elect A.N.M.C.O)
E. Bombardieri (President A.I.M.N.)
M. Chiariello (Past-President S.I.C.)
G. M. Sambuceti (Chairman EWG on Nuclear Cardiology)
G. Bissoni (Health Councilman - Regione Emilia Romagna)
M. Basenghi (General Director - AUSL Cesena)
G. Conti (Mayor of Cesena)
SCIENTIFIC PROGRAM
9.15
Inaugural Lecture:
Clinical Challenges and Future Molecular Trends
B. ZARET (Yale University - New Haven)
Introduced by P.L. PIERI (Cesena)
10.00 Keynote Address
Acute coronary syndromes revisited
A. MASERI (Vita - Salute University - Milano)
Introduced by G. BELLER (Virginia University - Charlottesville)
SESSION I
ACUTE CORONARY SYNDROMES
Chairmen: M. CHIARIELLO (Federico II University - Napoli)
T.VARETTO (Torino University)
10.30. Maturing Concepts of Chest Pain Centers
F. J. WACKERS (Yale University - New Haven)
10.50. Was it an ischemic episode?
Metabolism during ischemia and basis of nuclear imaging
J. UDELSON (Tufts University - Boston)
11.10 Coffee break
11.30 Assesment of microvascular integrity
G. SAMBUCETI (National Research Institute C.N.R. - Pisa)
11.50 Assessment of plaque vulnerability
J. NARULA (University of California - Irvine)
12.10 Panel Discussion and Clinical Cases
Chairmen: M. CHIARIELLO - T. VARETTO
Panelists: M. GALLI, J. NARULA, G. SAMBUCETI,
J. UDELSON, F. WACKERS, T. YASUDA
Clinical Case
Presenter: A. GALASSI (Catania University)
13.30 Lunch
SESSION II
HEART FAILURE - I
Chairmen: G. DI PASQUALE (Bologna) - E. INGLESE (Novara)
14.30 Lecture: Clinical trials and improved survival in heart failure:
Potential role for Nuclear Cardiologist?
P. PERRONE-FILARDI (Federico II University - Napoli)
Introduced by: M. CHIARIELLO (Federico II University - Napoli)
15.10 Myocardial metabolism and programmed cell survival
M. SCHWAIGER (Technischen University - Munchen)
15.30 Myocardial viability in the era of new drugs, and new surgical
techniques and devices
J. BAX (Leiden University)
15.50 Radionuclide Imaging in Heart Failure: Now and in the future
J. UDELSON (Tufts University - Boston)
16.10 Panel Discussion
Chairmen: G. DI PASQUALE - E. INGLESE
Panelists: J. BAX, J. DALLE MULE, A. ISKANDRIAN,
P. PERRONE-FILARDI, M. SCHWAIGER,
J. UDELSON
16.40 Coffee Break
SESSION III
17.00 CLINICAL CASES SESSION
Sponsored by Bristol-Myers-Squibb
Chairmen: A. ISKANDRIAN (University of Alabama - Birmingham)
P.L. PIERI (Cesena)
Cases: 1) Heart Failure imaged
Clinical Introduction: J. NARULA
(University of California - Irvine)
Case Presenter: J. DALLE MULE (Pieve di Cadore)
2) Imaging in asymptomatic diabetic pts
Clinical introduction: M. COMASCHI (Genova)
Case presenter: F. J. WACKERS (Yale University - New Haven)
3) Chest pain imaging
Clinical introduction: F. MIGLIO (Bologna)
Case presenter: R. SCIAGRA’ (Firenze University)
4) Stress Myocardial Perfusion Imaging in women
Clinical introduction: M.G. MODENA (Modena University)
Case Presenter: E. MILAN (Castelfranco Veneto)
5) Myocardial Perfusion Imaging in renal insufficiency
Clinical introduction: M. TIMIO (Foligno)
Case Presenter: O. SCHILLACI (Roma)
18.45 RECEPTION (Sponsored by Bristol-Myers-Squibb)
SESSION IV
CHRONIC CORONARY DISEASE - I
Chairmen: A. CUOCOLO (Federico II University - Napoli)
G. MAZZOTTA (Genova)
8.30
Lecture: Coronary flow dynamics at rest and stress:
Physical, Mental and Nouveau Pharmacologic Stressors
J. LEPPO (Pittsfield-USA)
Introduced by: P.L. PIERI (Cesena)
9.00
Myocardial perfusion assessment by echo, nuclear and MR
techniques
O. PARODI (National Research Institute-Milano)
9.20
Which is the best stressor for risk-stratification?
G. BELLER (University of Virginia - Charlottesville)
9.40
Nuclear cardiology in multicenter clinical trials
A. ISKANDRIAN (University of Alabama - Birmingham)
10.00 Panel Discussion
Chairmen: A. CUOCOLO - G. MAZZOTTA
Panelists: G. BELLER, A. ISKANDRIAN, J. LEPPO,
C. MARCASSA, O. PARODI, F. TARTAGNI
10.30 Coffee break
11.00 Keynote Address:
Lessons learnt from nuclear oncology
H. WILLIAM STRAUSS (Cornell University - New York)
Introduced by: P.L. PIERI (Cesena)
12,00 SATELLITE SYMPOSIUM
Sponsored by Amersham Health
Nuclear Cardiology- Forward Vision in Imaging
Chairmen: A. LAHIRI (London), P.L. PIERI (Cesena)
The women’s perspective: coronary artery disease
and congestive heart failure
J. MIERES (New York)
Congestive heart failure and value of cardiac
denervation assessment
I. CARRIO’ (Autonomous University - Barcelona)
Congestive heart failure: perfusion and sympathetic
innervation combination assessment
J. BAX (Leiden University)
Panel Discussion
"The Issue: Nuclear Medicine and Cardiology
Future growth of nuclear imaging"
Chairmen: P.L. PIERI (Cesena) - A. LAHIRI (London)
Panelists: J. BAX, I. CARRIO’, M. CHIARIELLO,
A. CUOCOLO, R. HENDEL, J. MIERES,
P. PERRONE-FILARDI, G. SAMBUCETI
13.30 Lunch (Sponsored by Amersham Health)
SESSION V
HEART FAILURE - II
Chairmen: R. HENDEL (Rush University - Chicago)
P. MARZULLO (National Research Institute - Pisa)
14.30 Lecture: Myocyte death and salvage beyond thrombolysis
J. NARULA (University of California, Irvine)
Introduced by: B. ZARET (Yale University - New Haven)
15.00 Nuclear imaging of ventricular remodeling
J. UDELSON (Tufts University - Boston)
15.20 Imaging in non ischemic cardiomyopathy
I. CARRIO’ (Autonomous University - Barcelona)
15.40 Stem cell support to failing myocardium
G. CONDORELLI (La Sapienza University - Roma)
Panel Discussion
Chairmen: R. HENDEL - P. MARZULLO
Panelists: I. CARRIO’, G. CONDORELLI, A. GIORDANO,
J. NARULA, J. UDELSON, P.L. ZANCO
16.45 Coffee break
SESSION VI
NEWER APPROACHES IN NUCLEAR TECHNOLOGY
Chairmen: M. SALVATORE (Federico II University - Napoli)
M. SCHWAIGER (Techinschen University - Munchen)
17.10 Angiogenesis: Surrogate markers of therapeutic efficacy
R. HENDEL (Rush University - Chicago)
17.30 Intravascular devices for atheroma detection and imaging
H. W. STRAUSS (Cornell University - New York)
17.50 Gene Product Imaging
B. ZARET (Yale University - New Haven)
18.10 Micro-SPECT and Micro-PET
E. GARCIA (Emory University - Atlanta)
Panel Discussion
Chairmen: M. SALVATORE - M. SCHWAIGER
Panelists: E. GARCIA, R. HENDEL, H. W. STRAUSS, B. ZARET
20.00 COCKTAIL AND GALA DINNER AT THE MEDIEVAL CASTLE
SESSION VII
9.00
YOUNG INVESTIGATOR AWARDS
Panel of Judges:
J. NARULA M. SCHWAIGER
H.W. STRAUSS
B. ZARET
SESSION VIII
CHRONIC CORONARY DISEASE - II
Chairmen: R. GIUBBINI (Brescia) - J. LEPPO (Pittsfield - USA)
10.45 Lecture: New cameras, new corrections and new concepts!
E. GARCIA (Emory University - Atlanta)
Introduced by: G. BISI (Torino University)
11.15 Monitoring effectiveness of therapy for coronary artery disease and
endothelial dysfunction using serial SPECT and PET
G. BELLER (Virginia University - Charlottesville)
11.35 Evaluation of ischemia after percutaneous or surgical revascularization
A. ISKANDRIAN (University of Alabama - Birmingham)
12.00 Is there a role of nuclear cardiology in screening of diabetic patients?
F. J. WACKERS (Yale University - New Haven)
Panel Discussion
Chairmen: R. GIUBBINI - J. LEPPO
Panelists: G. BISI, R. BELARDINELLI, G. BELLER, E. GARCIA,
A. ISKANDRIAN, T. EL KADI, M. MAZZANTI,
F. WACKERS, T. YASUDA
Concluding Remarks
P.L. PIERI - H.W. STRAUSS
Farewell light buffet
International Advisory Committee
A. Abreu (Portugal)
E. Alexanderson (Mexico City)
A.H. Allam (Cairo)
K.C. Allman (Concord, Australia)
C. Anagnostopoulos (London)
A. Antonopoulos (Athens)
M. Ayub (Lahore)
V.R. Balestrini (Cordoba, Argentina)
R. Beanlands (Ottawa)
D. Bialostozky (Mexico)
A. Bishof-Delaloye (Lausanne)
Hee-Seung Bom (South Korea)
T. Chua (Singapore)
J. Castell-Conesa (Barcelona)
J.F.B. Cuellar (Havana)
H. Dakik (Beirut)
P. G. Danias (Maroussi - Greece)
A. Al Fattah (Cairo)
R. Ferreira (Portugal)
P.R. Franken (Brussels)
S. B. Freedman (Concord, Australia)
M. R. Freeman (Toronto)
Z. H. He (Beijing)
B. Hesse (Coopenhagen)
D. P. Humen (London, ON, Canada)
A. Imam (Cairo)
T. El Kady (Cairo)
L. La Providencia (Coimbra)
R.D. Lele (Mumbai - India)
V. R. Lele (Bombay)
X.J. Liu (Beijing)
D. Jain (Philadelphia)
G. Lucignani (Milano)
S. Mahmood (Singapore)
J.C. Meneghetti (Sao Paolo)
M.J. Metcalfe (Aberdeen)
M. Milcinski (Liubliana)
A. Muxi (Barcelona)
F. Mut (Montevideo)
V. Naidoo (Cape Town)
E. Olea (Santiago)
M. Da Rocha Pantoja (Rio de Janeiro)
N.A. Perez-Balino (Buenos Aires)
V. Prassopoulos (Athens)
K. El Sabban (Cairo)
C. D. Samos-Ocampo (Manila)
P. Smanio (São Paulo)
A. Rahman Sharaf (Cairo)
I. Vassiliadis (Athens)
N.A. Vita (Rosario, Argentina)
B.L. Van Eck-Smit (Amsterdam)
S.J. Zakko (Dubai)
N. Zafrir (Israel)
SCIENTIFIC INFORMATION
CME Credits
Continuing Medical Education Credits will be assigned to italian and international
attendees: EACME for European participants; ECM for Italians and AMA
for US attendees.
Abstracts
Abstracts will be selected for poster and oral presentation. Abstracts must be
typed in English, following the instructions listed below. The abstracts must
be sent by mail, fax or e-mail (preferred) to the Scientific Secretariat:
Pier Luigi Pieri, MD
Chief, Division of Cardiovascular Medicine
Director, Nuclear Cardiology Unit
“M. Bufalini Hospital” Viale Ghirotti, 286 - 47023 Cesena - Italy
e-mail: [email protected]
Tel: +39 0547 352860 Fax: +39 0547 304010
The payment of the registration fee to the Organizing Secretariat is required.
The Scientific Committee will award the best 3 abstracts a “Nuclear Cardiology
Award - Cesena 2004”;
ABSTRACTS DEADLINE: APRIL 30, 2004
Confirmation of acceptance will be sent to the signing author by May 10, 2004.
Abstracts Instructions
The abstracts with title, author(s), address(es), text, must be printed on one A4
format page, double spaced. Underline the name of the author presenting the
posters. Print the title in capital letters.
Official languages
English and Italian, with simultaneous translation.
Slides
Only CD and computer presentation will be suitable.
CD must be handed to the Slide Center at least 30 minutes before the start of
the Session.
Exhibition Area
An exhibition area will be located inside the venue.
GENERAL INFORMATION
Venue
Teatro Comunale "A.Bonci" 47023 Cesena (FC) - Italy
Mobile phone +39 338 6887737 Organizing Secretariat
+39 335 8005995 Scientific Secretariat
How to reach the Meeting venue
By plane:
By car:
Rimini Airport (30 km from Cesena) or Forlì Airport (18 km),
then by train or Taxi to Cesena.
Highway A14, exit Cesena (not Cesena Nord) then
follow the signal "Centro" to reach the parking
(on Viale Carducci) close to the venue of the meeting
(follow the directions)
Organizing Secretariat
The Secretariat will be operating at the Meeting venue starting Wednesday,
June 9, 2004 (3.00 p.m.) and during the meeting.
Mobile phone +39 338 6887737
Registration
Register for the meeting by completing and returning the registration form
(enclosed) together with payment, to the Organizing Secretariat.
Attendance will be limited to 350 participants and early registration is therefore
advisable.
Registration fee
The registration fee is fixed in Euro 300.
It includes:
- Admittance to the scientific sessions
- Coffee breaks
- Lunches
- Welcome cocktail party and gala dinner at the castle
- Bus transportation to the meeting from the hotels located in Cesenatico and
Milano Marittima and viceversa.
Attendance Certificates
Attendance certificates will be issued to all participants who will make request
to the Organizing Secretariat.
Proceedings of the Meeting
The Proceedings of the meeting, including the accepted abstracts, will be
published in "THE QUARTERLY JOURNAL OF NUCLEAR MEDICINE"
quoted in: Excerpta Medica, Index Medicus etc.
Hotel accommodation
Hotel reservations should be made by sending the enclosed “Hotel
Accommodation Form” to the Organizing Secretariat not later than May 15,
2004.
Cancellations
In case of cancellations before May 15, 2004 (notification must be received
in writing to the Organizing Secretariat) the fees will be refunded (minus an
administrative fee of 30%) after the meeting. No refunds will be made for
cancellations made after May 25, 2005.
Social events
Thursday, June 10
6.45 p.m.
Reception
Friday, June 11
8.00 p.m.
Welcome cocktail party and dinner at the Rocca Malatestiana
(a XV century castle). Admission included in the registration
fee.
Saturday, June 12
Guided visits to the Malatestiana Library
Variations
The Scientific Committee and the Organizing Secretariat reserve the right to
make necessary change to the program due to the technical or scientific reasons.
The Organizing Committee wishes to extend its special thanks to the Institutions
and Companies who helped make this meeting possible:
INSTITUTIONS
REGIONE EMILIA-ROMAGNA
COMUNE DI CESENA
AZIENDA USL-CESENA
SPONSORS
AMERSHAM HEALTH
BRISTOL-MYERS-SQUIBB
A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE
LABORATORI GUIDOTTI S.p.A.
SIGMA TAU S.p.A.
FUJISAWA HEALTHCARE Inc.
SIEMENS MEDICAL
PFIZER
BRACCO S.p.A
FONDAZIONE CASSA DI RISPARMIO DI CESENA
GENERAL ELECTRIC MEDICAL SYSTEM
BRACCO DIAGNOSTICS
ABBOTT
PHILIPS MEDICAL SYSTEMS
MOLECULAR INSIGHT PHARMACEUTICALS, Inc.
BAYER
MiE GmbH
LUSOFARMACO
KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, Inc.
AVENTIS PHARMA S.p.A
SANOFI -SYNTHELABO S.p.A.
SERVIER
ALTANA PHARMA S.p.A.
A special thank to
“Associazione per la lotta alle Malattie Cardiovascolari” of Cesenatico
and to the Fishermen of Cesenatico
The miniatures reproduced in this brochure
are taken from codices of the Malatestiana Library of Cesena.
We thank its Director Daniela Savoia for the permission.
Photos by Ivano Giovannini
Cesena - Biblioteca Malatestiana (sec. XV)