Dr Francesco Benedetti Curriculum vitae Francesco Benedetti, M.D. Curriculum Vitae February 7, 2012 Contacts: Istituto Scientifico Universitario Ospedale San Raffaele Department of Clinical Neurosciences San Raffaele Turro via Stamira D'Ancona 20 20127 Milano Italy Phone: + 39 02 2643 3310 Fax: + 39 02 2643 3265 e-mail: [email protected] 1 Dr Francesco Benedetti Curriculum vitae Personal Informations Born: Citizenship: March 3, 1966 in Modena, Italy Italian Education, licensure and certification Certifications: Italian medical licensure Diplomate in Psychiatry Diplomate in Clinical Psychology Residency: Clinical Psychology, University of Milan, Italy Psychiatry, University Vita-Salute San Raffaele, Milan, Italy Graduate: School of Medicine (1991), University of Modena, Italy. Current appointments - Head – Clinical Research Group Psychiatry and Clinical Neurosciences – Division of Neuroscience - Ospedale San Raffaele, Milano (2009) Area coordinator – Department of Clinical Neurosciences - Ospedale San Raffaele (2007) Contract Professor of Psychiatry, School of Medicine (degree in Medicine, residency in Psychiatry), University Vita-Salute San Raffaele, Milano (2002) Membership in scientific institutions - Collegium Internationale Neuro-Psychopharmacologicum (CINP), Education Committee European College of Neuropsychopharmacology (ECNP) International Society for Affective Disorders - Committee on Chronotherapeutics in Affective Disorders (https://www.isad.org.uk/ccad.html) Center for Environmental Therapeutics (www.chronotherapeutics.org), scientific board Operating Committee of the Centro di Eccellenza Risonanza Magnetica ad Alto Campo di Milano (C.E.R.M.A.C.) (Center of Excellence for High-Field Magnetic Resonance Imaging), funded by the Italian Ministry of Health and the Italian Ministry of University and Scientific Research Francesco Benedetti (total cites 2759, h-index = 31) authored scientific publications since 1996 on peer-reviewed international journals. During his career he combined his research activities with clinical work, mainly in the field of mood disorders, with university teaching appointments, and with coordination and leadership of research units. His main research interests are within the field of translational and reverse-translational research in psychiatry (see list of publications), and include chronobiology and chronotherapeutics of mood disorders (A), psychiatric genetics and clock genes (B), brain imaging and neural correlates of psychiatric diseases and therapeutics (C). Other areas of interest (D) include clinical neuropsychology and animal models of psychiatric diseases. 2 Dr Francesco Benedetti Curriculum vitae Training and Experiences 1988-1991 1992-1993 1993-1994 1994-1995 1995-2001 2002 – 2009 – Pre-doctoral research fellow at the Institute of Human Physiology, State University of Modena (Prof. E.A. Moja, Prof. L.F. Agnati). Post-doctoral research fellow at the Chair of Medical Psychology, Institute of Psychology, State University of Milan (Prof. E.A. Moja). Italian Army (military obligation), Medical Lieutenant Post-doctoral research fellow at the Chair of Psychiatry, Department of Neuropsychiatric Sciences, Istituto Scientifico Ospedale San Raffaele, State University of Milan (Prof. E. Smeraldi). Staff Psychiatrist at the Mood Disorder Unit, Psychiatric Branch, Istituto Scientifico Ospedale San Raffaele Area Coordinator (Scientific research activities) at the Department of Clinical Neurosciences, Istituto Scientifico Ospedale San Raffaele. Head – Clinical Research Group Psychiatry and Clinical Neurosciences – Division of Neuroscience - Istituto Scientifico Ospedale San Raffaele. With a matrix structure, this research group includes people and structures affiliated to (1) the Department of Clinical Neurosciences of the Ospedale San Raffaele, including the units of psychiatry (7 wards, 120 beds, 2 day-hospital services, two outpatient services), sleep medicine (10 beds), and clinical psychology; (2) the Chairs of Psychiatry and Clinical Psychology of the Università Vita-Salute San Raffaele; and (3) the research units of Psychiatry and Clinical Psychobiology, Sleep Medicine, and Clinical Psychology of the Division of Neuroscience of the San Raffaele Scientific Institute. Being the Head of the Research Group, F.B. personally directs the unit of Psychiatry and Clinical Psychobiology, and coordinates the other group leaders’ activities. Research activities focus at the interface between neuroscience and behavioral disorders, with the aim of increasing scientific knowledge and developing effective diagnosis and treatment options in the broad field of Psychiatry and Clinical Neurosciences. Areas of expertise encompass clinical psychobiology, in vivo imaging, genetics, pharmacology, neuropsychology, neurophysiology, and clinical research, to face the questions of modern clinical psychiatry, neurology, and clinical psychology. Facilities include a in-house psychiatric genetics laboratory (since 1990), access to a 3.0 T MRI scanner in a dedicated research center (C.E.R.M.A.C., 2005), and a molecular biology laboratory for animal research (2010). Clinical and research activities began in 1988, and has increased over time. A simple Medline search (Jan 09) restricted to the previous 10 years allows a rough quantitation of recent scientific products by giving 226 papers in the field of psychiatry; 106 in the field of sleep medicine; and 25 in the field of clinical psychology. In the field of psychiatry the outstanding achievements have been matter for independent investigations by lay media in the years 2004 and 2006: the evaluation of the total Impact Factor ranked the psychiatric branch of the group at the 1st place among all psychiatric research structures in Italy (our I.F. 225.7 vs 60.1 second place in 2004), and at the third place in western Europe (2006, I.F. 417.0 in the field of mood disorders). 3 Dr Francesco Benedetti Curriculum vitae Teaching Appointments - University 1998-1999 Assistant Professor – Chair of Psychiatry - University of Milano, Italy 2000-2002 Assistant Professor – Chair of Psychiatry – University Vita-Salute San Raffaele, Milano 2006-2010 Contract professor of General Psychopathology, School of Psychology, Università Vita-Salute San Raffaele. 2003 –present Contract professor of Psychiatry, School of Medicine, Università Vita-Salute San Raffaele, Milano. Course on “Ethics and psychiatry of suicide”, required for first year residents, and elective for fourth-sixth year students in medicine and third-fifth year students in clinical psychology. Teaching Appointments - Others Coordinator of teaching activities and primary lecturer - European Social Fund, Italian Ministry of Employment, Regione Lombardia – Advanced Post-doctoral Educational Program - Course Project 3 D4 n.34026; and CME Program of the Italian Ministry of Health, Course Projects n.4403-11548 and 11550 – “Non-pharmacological treatment of major depression.” (2002). Coordinator of teaching activities and primary lecturer - European Social Fund, Italian Ministry of Employment, Regione Lombardia – Advanced Pre-doctoral Educational Program - Course Project n.88956 – “Psychometric techniques in clinical practice.” (2003) Coordinator of scientific activities and lecturer - European Social Fund, Italian Ministry of Employment, Regione Lombardia – Advanced Post-doctoral Educational Program; and CME Program of the Italian Ministry of Health, Course Project n.4403-44457. “Sleep Deprivation and Chronobiology of Depression”, Milano (2003). Boards, Reviewer, Scientific advisor 2011 - Co-editor of Neurology, Psychiatry and Brain Research (prev. Zentralblatt fur die gesamte Neurologie und Psychiatrie), Elsevier Science Publishing (http://ees.elsevier.com/npbr/ ) Editorial board: 2011 - Rivista di Psichiatria ( http://www.rivistadipsichiatria.it/ ) The Open Psychiatry Journal (http://www.bentham.org/open/topj/EBM.htm) The Open Magnetic Resonanace Journal (www.bentham.org/open/tomrj) Reviewer : University of California – Irvine; Swiss National Science Foundation; American Journal of Medical Genetics; American Journal of Psychiatry; Annals of Medicine; Archives of General Psychiatry; 4 Dr Francesco Benedetti Arthritis Research & Therapy; Biological Psychiatry; BioMedCentral Psychiatry; BioMedCentral Neuroscience; Bipolar Disorders; Chronobiology International; Current Psychiatry Reviews; Depression and Anxiety; European Child & Adolescent Psychiatry; European Neuropsychopharmacology; Future Medicine – Therapy; International Journal of Neuropsychopharmacology; Journal of Affective Disorders; Journal of Biological Rhythms; Journal of Circadian Rhythms; Journal of Clinical Psychiatry; Journal of Clinical Psychopharmacology; Journal of Psychiatric Research; Curriculum vitae Journal of Psychopharmacology; Journal of Sleep Research; Molecular Psychiatry; NeuroImage Neuropsychologia; Neuropsychopharmacology; Neuroradiology; Neuroscience and Biobehavioral Reviews; Neuroscience Letters; Nutritional Neuroscience; Pharmacopsychiatry; Progress in Neuropsychopharmacology and Biological Psychiatry; Psychiatry Investigation; Psychiatry Research; Schizophrenia Research; The Lancet; The Pharmacogenomics Journal; The World Journal of Biological Psychiatry. Grants 2008-2012 € 520 000. European Union FP7 grant 222963 (Health 2007-2.2.1-8 From Mood disorders to experimental models) – “MOODINFLAME: Early diagnosis, treatment and prevention of mood disorders targeting the activated inflammatory response system” (P.I.). 2005-2007 € 35 000. Italian Ministry of University and Scientific Research, PRIN project n. 2004061180 “Genetic and neural imaging aspects of antidepressant response” (co-investigator) 2004-2006 € 450 000. Unrestricted research grant from Janssen-Cilag S.p.A. (Italy) to Vita-Salute San Raffaele University-C.E.R.M.A.C. for the acquisition and maintenance of a 3.0 T magnetic resonance imaging scanner (co-investigator) 2003 € 54 000. European Union and Italian Ministry of Employment - Educational grant for project n.88956 – “Psychometric techniques in clinical practice.” (Coordinator) 2001-2002 € 150 000. European Union and Italian Ministry of Employment - Educational grant for projects n.4403-11548 and 11550 – “Non-pharmacological treatment of major depression.” (Coordinator) 5 Dr Francesco Benedetti Curriculum vitae List of Publications (thematic and chronological order, earliest to latest) Journal Articles, peer reviewed – Full papers A. Chronobiology and chronotherapeutics of mood disorders 1. Benedetti F, Barbini B, Colombo C, Campori E, Smeraldi E (1996) Infradian mood fluctuations during a major depressive episode. Journal of Affective Disorders, 41(2):81-87. 2. Benedetti F, Barbini B, Campori E, Colombo C, Smeraldi E (1996) Dopamine agonist amineptine prevents the antidepressant effect of sleep deprivation. Psychiatry Research, 65(3):179-184. 3. Benedetti F, Barbini B, Lucca A, Campori E, Colombo C, Smeraldi E (1997) Sleep deprivation hastens the antidepressant action of fluoxetine. European Archives of Psychiatry and Clinical Neurosciences, 247(2):100-103. 4. Benedetti F, Barbini B, Campori E, Colombo C, Smeraldi E (1998) Patterns of mood variation during antidepressant treatment. Journal of Affective Disorders, 49(2):133-139. 5. Barbini B, Colombo C, Benedetti F, Campori E, Bellodi L, Smeraldi E. (1998) The unipolar/bipolar dichothomy and the response to sleep deprivation. Psychiatry Research, 79(1):43-50. 6. Smeraldi E, Benedetti F, Campori E. (1998) Sustaining the effect of sleep deprivation [letter]. American Journal of Psychiatry, 155(8):1134-1135. 7. Barbini B, Benedetti F, Colombo C, Guglielmo E, Campori E, Smeraldi E. (1998) Perceived mood and biological rhythms in depression. European Archives of Psychiatry and Clinical Neurosciences, 248(3):157-160. 8. Benedetti F, Zanardi R, Colombo C, Smeraldi E. (1999) Worsening of delusional depression after sleep deprivation: case reports. Journal of Psychiatric Research, 33(1): 69-72. 9. Smeraldi E, Benedetti F, Barbini B, Campori C, Colombo C (1999) Sustained antidepressant effect of sleep deprivation combined with pindolol in bipolar depression: a placebocontrolled trial. Neuropsychopharmacology, 20(4):380-385. 10. Benedetti F, Barbini B, Campori E, Colombo C, Smeraldi E. (1999) Ongoing lithium treatment prevents relapse after sleep deprivation. Journal of Clinical Psychopharmacology, 19(3):240-245. 11. Colombo C, Benedetti F, Barbini B, Campori E, Smeraldi E. (1999) Rate of switch from depression into mania after therapeutic sleep deprivation in bipolar depression. Psychiatry Research, 86(3):267-270. 6 Dr Francesco Benedetti Curriculum vitae 12. Colombo C, Lucca A, Benedetti F, Barbini B, Campori E, Smeraldi E (2000) Total sleep deprivation combined with lithium and light therapy in the treatment of bipolar depression: replication of main effects and interaction. Psychiatry Research, 95(1):43-53. 13. Benedetti F, Colombo C, Barbini B, Campori E, Smeraldi E (2001) Morning sunlight reduces lenght of hospitalization for bipolar depression. Journal of Affective Disorders, 62(3):221223. 14. Benedetti F, Campori E, Barbini B, Cigala Fulgosi M, Colombo C (2001) Dopaminergic augmentation of sleep deprivation effects in bipolar depression. Psychiatry Research, 104(3):239-246. 15. Benedetti F, Barbini B, Campori E, Cigala Fulgosi M, Pontiggia A., Colombo C (2001) Sleep phase advance and lithium to sustain the antidepressant effect of total sleep deprivation in bipolar depression: new findings sustaining the internal coincidence model? Journal of Psychiatric Research, 35(6):323-329. 16. Benedetti F, Lucca A, Brambilla F, Colombo C, Smeraldi E (2002) Interleukine-6 serum levels correlate with response to antidepressant sleep deprivation and sleep phase advance . Progress in Neuro-Psychopharmacology and Biological Psychiatry, 26:1167-1170. 17. Benedetti F, Colombo C, Serretti A, Pontiggia A, Bernasconi A, Florita M, Smeraldi E (2003) Morning light treatment hastens the antidepressant effect of citalopram: a placebo controlled trial. Journal of Clinical Psychiatry, 64(6):648-653. 18. Benedetti F, Pontiggia A, Bernasconi A, Colombo C, Florita M, Smeraldi E (2004) Lormetazepam in depressive insomnia: new evidences for phase-response effects of benzodiazepines. International Clinical Neuropsychopharmacology, 19(5):311-317. 19. Wirz-Justice A, Benedetti F, Berger M, Lam RW, Martiny K, Terman M, Wu JC (2005) Chronotherapeutics (light and wake therapy) in affective disorders. Psychological Medicine, 35(7):939-944. 20. Barbini B, Benedetti F, Colombo C, Dotoli D, Bernasconi A, Cigala Fulgosi M, Florita M, Smeraldi E (2005) Dark therapy for mania: a pilot study. Bipolar Disorders, 7(1):98-101. 21. Benedetti F, Barbini B, Florita M, Cigala Fulgosi M, Campori E, Colombo C, Smeraldi E (2005) Rapid improvement in information processing after sleep deprivation and sleep phase-advance in bipolar depression. Clinical Psychiatry, 2(3):180-182. 22. Benedetti F, Barbini B, Cigala Fulgosi M, Colombo C, Dallaspezia S, Pontiggia A, Smeraldi E (2005) Long term effects of combined total sleep deprivation and light therapy in the treatment of drug-resistant bipolar depression. Journal of Clinical Psychiatry, 66(12):15351540. 23. Benedetti F, Barbini B, Colombo C, Smeraldi E (2007) Chronotherapeutics in a psychiatric ward. Sleep Medicine Reviews, 11(6):509-22. 7 Dr Francesco Benedetti Curriculum vitae 24. Benedetti F, Dallaspezia S, Cigala Fulgosi M, Barbini B, Colombo C, Smeraldi E (2007) Phase advance is an actimetric correlate of antidepressant response to sleep deprivation and light therapy in bipolar depression. Chronobiology International, 24(5):921-37 25. Benedetti F, Smeraldi E (2007) Comment on the potential role of ghrelin in the mechanism of sleep deprivation therapy for depression. [letter] Sleep Medicine Reviews, 11(6):524-5. 26. Benedetti F, Fresi F, Maccioni P, Smeraldi E (2008) Behavioural sensitization to repeated sleep deprivation in a mice model of mania. Behavioural Brain Research, 187(2):221-7. 27. Benedetti F, Smeraldi E (2009) Neuroimaging and genetics of antidepressant response to sleep deprivation: implications for drug development. Current Pharmaceutical Design, 15(22):2637-49. 28. Dallaspezia S, Benedetti F (2009) Melatonin, circadian rhythms, and the clock genes in bipolar disorder. Current Psychiatry Reports, 11(6):488-93. 29. Dallaspezia S, Benedetti F (2011) Chronobiological therapy for mood disorders. Expert Reviews of Neurotherapeutics, 11(7):961-70. 30. Benedetti F, Colombo C (2011) The use of sleep deprivation in mood disorders. Neuropsychobiology, 64:141–151. 31. Wirz-Justice A, Bader A, Frisch U, Stieglitz RD, Alder J, Bitzer J, Hösli I, Jazbec S, Benedetti F, Terman M, Wisner K, Riecher-Rössler A. A randomized, double-blind, placebo-controlled study of light therapy for antepartum depression. Journal of Clinical Psychiatry, 72(7):98693. B. Psychiatric genetics 32. Smeraldi E, Zanardi R, Benedetti F, Di Bella D, Perez J, Catalano M (1998) Polymorphism within the promoter of the serotonin transporter gene and antidepressant efficacy of fluvoxamine. Molecular Psychiatry, 3(6):508-511. 33. Benedetti F, Serretti A, Colombo C, Campori E, Barbini B, Di Bella D, Smeraldi E. (1999) Influence of a functional polymorphism within the promoter of the serotonin transporter gene on the effects of total sleep deprivation in bipolar depression. American Journal of Psychiatry, 156(9):1450-1452. 34. Serretti A, Benedetti F, Colombo C, Lilli R, Lorenzi C, Smeraldi E (1999) Dopamine receptor D4 is not associated with antidepressant activity of sleep deprivation. Psychiatry Research, 89(2):107-114. 8 Dr Francesco Benedetti Curriculum vitae 35. Zanardi R, Benedetti F, Di Bella D, Catalano M, Smeraldi E (2000) Efficacy of paroxetine in depression is influenced by a functional polymorphism within the promoter of the serotonin transporter gene. Journal of Clinical Psychopharmacology, 20(1):105-107. 36. Benedetti F, Serretti A, Colombo C, Campori E, Barbini B, Di Bella D, Smeraldi E (2000) Some ado for a polymorphism [letter; reply]. American Journal of Psychiatry, 157(11):18871888. 37. Schumann G, Benedetti F, Voderholzer U, Kammerer N, Hemmeter U, Travers HW, Fiebich B, Holsboer-Trachsler E, Berger M, Seifritz E, Ebert D (2001) Antidepressive response to sleep deprivation in unipolar depression is not associated with dopamine D3 receptor genotype. Neuropsychobiology, 43(3):127-130. 38. Smeraldi E, Benedetti F, Zanardi R (2002) Serotonin transporter promoter genotype and illness recurrence in mood disorders. European Neuropsychopharmacology, 12(1):73-75. 39. Benedetti F, Serretti A, Colombo C, Lilli R, Lorenzi C, Smeraldi E (2003) Dopamine receptor D2 and D3 gene variants are not associated with the antidepressant effect of total sleep deprivation in bipolar depression. Psychiatry Research, 118(3):241-247. 40. Benedetti F, Colombo C, Serretti A, Lorenzi C, Pontiggia A, Barbini B, Smeraldi E (2003) Antidepressant effects of light therapy combined with sleep deprivation are influenced by a functional polymorphism within the promoter of the serotonin transporter gene. Biological Psychiatry, 54(7):687-692. 41. Serretti A, Benedetti F, Mandelli L, Lorenzi C, Pirovano A, Colombo C, Smeraldi E (2003) Genetic dissection of psychopathological symptoms: insomnia in mood disorders and CLOCK gene polymorphism. American Journal of Medical Genetics, 121B(1):35-8. 42. Benedetti F, Serretti A, Colombo C, Lorenzi C, Tubazio V, Smeraldi E. (2004) A glycogen synthase kinase 3-β promoter gene SNP is associated with age at onset and response to total sleep deprivation in bipolar depression. Neuroscience Letters, 368(2)123-126. 43. Cavallaro R, Lattuada E, Benedetti F, Lorenzi C, Smeraldi E (2004) Genetic dissection of drug side effects in clinical practice: CLOCK gene and clozapine-induced diurnal sleepiness. Neuroscience Letters, 367(2)152-155. 44. Benedetti F, Serretti A, Pontiggia A, Bernasconi A, Lorenzi C, Colombo C, Smeraldi E (2005) Long-term response to lithium salts in bipolar illness is influenced by the glycogen synthase kinase 3-β -50 T/C SNP. Neuroscience Letters, 376(1):51-55. 45. Serretti A, Cusin C, Benedetti F, Mandelli L, Pirovano A, Zanardi R, Colombo C, Smeraldi E (2005) Insomnia improvement during antidepressant treatment and CLOCK gene polymorphism. American Journal of Medical Genetics, B, 137(1):36-39. 46. Benedetti F, Serretti A, Colombo C, Barbini B, Lorenzi C, Campori E, Smeraldi E (2003) Influence of CLOCK gene polymorphism on circadian mood fluctuation and illness recurrence in bipolar depression. American Journal of Medical Genetics, 123B(1):23-26. 9 Dr Francesco Benedetti Curriculum vitae 47. Benedetti F, Bernasconi A, Lorenzi C, Pontiggia A, Serretti A, Colombo C, Smeraldi E (2004) Glycogen synthase kinase 3-b influences age at onset of bipolar disorder. Neuroscience Letters, 355(1-2):37-40. 48. Serretti A, Benedetti F, Zanardi R, Smeraldi E (2005) The influence of SERTPR and other polymorphisms of the serotonin pathway on the efficacy of antidepressant treatments. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 29:1074-1084. 49. Benedetti F, Dallaspezia S, Cigala Fulgosi M, Lorenzi C, Serretti A, Barbini B, Colombo C, Smeraldi E (2007) Actimetric evidence that CLOCK 3111 T/C SNP influences depressive insomnia and activity patterns in bipolar depression. American Journal of Medical Genetics - B - Neuropsychiatric Genetics 144B(5): 631-635 50. Serretti A, Benedetti F, Mandelli L, Calati R, Caneva B, Lorenzi C, Fontana V, Colombo C, Smeraldi E (2008) Association between GSK-3β –50T/C polymorphism and psychotic symptoms in mood disorders. Psychiatry Research, 158(2):132-140. 51. Artioli P, Lorenzi C, Pirovano A, Serretti A, Benedetti F, Catalano M, Smeraldi E (2008) How do genes exert their role? Period 3 gene variants and possible influences on mood disorder phenotypes. European Neuropsychopharmacology, 17(9):587-94. 52. Benedetti F, Barbini B, Bernasconi A, Cigala Fulgosi M, Campori E, Colombo C, Dallaspezia S, Lorenzi C, Pontiggia A, Radaelli D, Smeraldi E (2008) Lithium overcomes the influence of 5-HTTLPR gene polymorphism on antidepressant response to sleep deprivation. Journal of Clinical Psychopharmacology, 28(2):249-51. 53. Benedetti F, Barbini B, Bernasconi A, Cigala Fulgosi M, Colombo C, Gavinelli C, Marino E, Pirovano A, Radaelli D, Smeraldi E (2008) Serotonin 5-HT2A receptor gene variants influence antidepressant response to repeated total sleep deprivation in bipolar depression. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 32:1833-1866. 54. Benedetti F, Dallaspezia S, Colombo C, Pirovano A, Marino E, Smeraldi E (2009) A length polymorphism in the circadian clock gene Per3 influences age at onset of bipolar disorder. Neuroscience Letters, 445(2):184-7. 55. Benedetti F, Colombo C, Pirovano A, Marino E, Smeraldi E (2009) The catechol-Omethyltransferase Val(108/158)Met polymorphism affects antidepressant response to paroxetine in a naturalistic setting. Psychopharmacology, 203(1):155-60. 56. Benedetti F, Barbini B, Bernasconi A, Cigala Fulgosi M, Dallaspezia S, Gavinelli C, Locatelli C, Lorenzi C, Pirovano A, Radaelli D, Smeraldi E, Colombo C (2010) Acute antidepressant response to sleep deprivation combined with light therapy is influenced by the catechol-Omethyltransferase Val(108/158)Met polymorphism. Journal of Affective Disorders, 121(12):68-72. 10 Dr Francesco Benedetti Curriculum vitae 57. Benedetti F, Dallaspezia S, Colombo C Lorenzi C, Pirovano A, Smeraldi E (2010) Effect of catechol-O-methyltransferase Val(108/158)Met polymorphism on antidepressant efficacy of fluvoxamine. European Psychiatry, 25(8):476-478. 58. Benedetti F, Dallaspezia S, Colombo C, Lorenzi C, Pirovano A, Smeraldi E (2010) Association between catechol-O-methyltransferase Val(108/158)Met polymorphism and psychotic features of bipolar disorder. Journal of Affective Disorders, 125:341-4. 59. Dallaspezia S, Benedetti F, Lorenzi C, Pirovano A, Colombo C, Smeraldi E (2011) Circadian clock gene Per3 variants influence the post-partum onset of bipolar disorder. European Psychiatry, 26(3):138-40. 60. Benedetti F,Radaelli D, Poletti S, Dallaspezia S, Locatelli C, Lorenzi C, Pirovano A, Colombo C, Smeraldi E (2011) Association of the C(-1019)G 5-HT1A promoter polymorphism with exposure to stressors before bipolar depression. Journal of Affective Disorders, 132:293-6 61. Benedetti F, Dallaspezia S, Locatelli C, Radaelli D, Poletti S, Lorenzi C, Pirovano A, Colombo C, Smeraldi E (2011) Recurrence of bipolar mania is associated with catechol-Omethyltransferase Val(108/158)Met polymorphism. Journal of Affective Disorders, 132:297-300 62. Benedetti F, Dallaspezia S, Lorenzi C, Pirovano A, Radaelli D, Locatelli C, Poletti S, Colombo C, Smeraldi E Gene-gene interaction of glycogen synthase kinase 3-B and serotonin transporter on human antidepressant response to sleep deprivation. Journal of Affective Disorders, in press. DOI information: 10.1016/j.jad.2011.10.039 C. Brain imaging and neural correlates of psychiatric diseases 63. Benedetti F, Bernasconi A, Pontiggia A (2006) Depression and neurological disorders. Current Opinions in Psychiatry, 19:14-18. 64. Benedetti F, Bernasconi A, Blasi V, Cadioli M, Colombo C, Falini A, Lorenzi C, Radaelli D, Scotti G, Smeraldi E (2007) Neural and genetic correlates of antidepressant response to sleep deprivation: a fMRI study of moral valence decision in bipolar depression. Archives of General Psychiatry, 64:179-187. 65. Benedetti F, Radaelli D, Bernasconi A, Dallaspezia S, Falini A, Lorenzi C, Scotti G, Colombo C, Smeraldi E (2008) Clock genes beyond the clock: CLOCK genotype biases neural correlates of moral valence decision in patients affected by bipolar depression. Genes Brain and Behaviour, 7(1):20-5. 66. Radaelli D, Bernasconi A, Benedetti F (2008) Advanced MRI techniques in: Psychiatric diseases. Neurological Sciences, 29 Suppl 3:339-41. 11 Dr Francesco Benedetti Curriculum vitae 67. Benedetti F, Calabrese G, Bernasconi A, Cadioli M, Colombo C, Dallaspezia S, Falini A, Radaelli D, Scotti G, Smeraldi E (2009) Spectroscopic correlate of antidepressant response to sleep deprivation and light therapy: a 3.0 T study of bipolar depression. Psychiatry Research Neuroimaging, 173(3):238-42 68. Benedetti F, Radaelli D, Bernasconi A, Dallaspezia S, Colombo C, Smeraldi E (2009) Changes in medial prefrontal cortex neural responses parallel successful antidepressant combination of venlafaxine and light therapy. Archives Italiennes de Biologie, 147:83-93 69. Fusar-Poli P, Placentino A, Carletti F, Landi P, Allen P, Surguladze S, Benedetti F, Abbamonte M, Gasparotti R, Barale F, Perez J, McGuire P, Politi PF (2009) Functional atlas of emotional faces processing: a voxel based (ALE) meta-analysis of 105 fmri studies. Journal of Psychiatry and Neuroscience, 34(6):418-32. 70. Benedetti F, Bernasconi A, Bosia M, Cavallaro R, Dallaspezia S, Falini A, Poletti S, Radaelli D, Riccaboni R, Scotti G, Smeraldi E (2009) Functional and structural brain correlates of theory of mind and empathy deficits in schizophrenia. Schizophrenia Research, 114(1-3):154-60 71. Benedetti F, Poletti S, Radaelli D, Bernasconi A, Cavallaro R, Falini A, Dallaspezia S, Lorenzi C, Pirovano A, Locatelli C, Scotti G, Smeraldi E (2010) Temporal lobe grey matter volume in schizophrenia is associated with a genetic polymorphism influencing glycogen synthase kinase 3-β activity. Genes Brain and Behavior, 9(4):365-71. 72. Benedetti F, Radaelli D, Poletti S, Falini A, Cavallaro R, Dallaspezia S, Riccaboni R, Scotti G, Smeraldi E (2011) Emotional reactivity in chronic schizophrenia: structural and functional brain correlates and the influence of adverse childhood experiences. Psychological Medicine, 41(3):509-19. 73. Benedetti F, Ping-Hong Yeh, Bellani M, Radaelli D, Nicoletti MA, Poletti S, Falini A, Dallaspezia S, Colombo C, Scotti G, Smeraldi E, Soares JC, Brambilla P (2011) Disruption of white matter integrity in bipolar depression as a possible structural marker of illness. Biological Psychiatry, 69(4):309-17. 74. Benedetti F, Absinta M, Rocca M, Radaelli D, Poletti S, Bernasconi A, Dallaspezia S, Pagani E, Falini A, Colombo C, Comi G, Smeraldi E (2011) Tract-specific white matter structural disruption in patients with bipolar disorder. Bipolar Disorders, 13(4):414-424 75. Benedetti F,Radaelli D, Poletti S, Locatelli C, Falini A, Colombo C, Smeraldi E. Opposite effects of suicidality and lithium on grey matter volumes in bipolar depression. Journal of Affective Disorders, 135 (1-3):139-147 76. Radaelli D, Poletti S, Dallaspezia S, Colombo C, Smeraldi E, Benedetti F (2012) Neural responses to emotional stimuli in comorbid Borderline Personality Disorder and Bipolar Depression. Psychiatry Research- Neuroimaging, in press 77. Benedetti F, Poletti S, Radaelli D, Pozzi E, Giacosa C, Ruffini C, Falini A, Smeraldi E (2012) Caudate grey matter volume in obsessive-compulsive disorder is influenced by adverse 12 Dr Francesco Benedetti Curriculum vitae childhood experiences and ongoing drug treatment. Journal of Clinical Psychopharmacology, in press D. Others 78. Moja EA, Rocchi E, Benedetti F, Paolillo F, Casalgrandi G, Ponz de Leon M (1991) Decrease in plasma tryptophan after a tryptophan-free amino acid solution. A comparison between cirrhotic and control subjects. Life Sciences, 48:409-418. 79. Benedetti F, Moja EA (1993) Failure of a tryptophan-free amino acid mixture to modify sexual behavior in the female rat. Physiology and Behavior, 53:575-579. 80. Moja EA, Benedetti F (1996) Sexual behavior in male and female rats after tryptophan-free diet. Advances in Experimental Medicine and Biology, 398:89-91. 81. Moja EA, Lucini V, Benedetti F, Lucca A (1996) Decrease in plasma phenylalanine and tyrosine after phenylalanine-tyrosine free amino acid solutions in man. Life Sciences, 58(26):2389-2395. 82. Barbini B, Scherillo P, Benedetti F, Crespi G, Colombo C, Smeraldi E. (1997) Response to clozapine in acute mania is more rapid than that of chlorpromazine. International Clinical Psychopharmacology, 12 (2):109-112. 83. Benedetti F, Sforzini L, Colombo C, Maffei C, Smeraldi E. (1998) Low-dose clozapine in acute and continuation treatment of severe borderline personality disorder. Journal of Clinical Psychiatry, 59(3):103-107. 84. Benedetti F, Cavallaro R, Smeraldi E (1999) Olanzapine-induced neutropenia after clozapine-induced neutropenia. The Lancet, 354(9178):567. 85. Benedetti F, Campori E, Colombo C, Smeraldi E (2004) Fluvoxamine treatment of major depression associated with multiple sclerosis. Journal of Neuropsychiatry and Clinical Neurosciences, 16(3):364-366. 86. Benedetti F, Barbini B, Cigala Fulgosi M, Pontiggia A, Colombo C, Smeraldi E (2005) Cognitive assessment of depression: a new test for mood disorders. Clinical Psychiatry, 2(3):149-165. 87. Florita M, Bernasconi A, Santoro A, Pontiggia A, Benedetti F (2005) Specificity of depressive core in cardiosurgery department. Clinical Psychiatry, 2(3):168-173. 88. Santoro A, Florita M, Rossini D, Benedetti F, Lucca A (2005) The processing of emotional stimuli in subjects with a major depressive episode treated with rTMS. Clinical Psychiatry, 2(3):184-188. 13 Dr Francesco Benedetti Curriculum vitae 89. Benedetti F, Anselmetti S, Florita M, Radaelli D, Cavallaro R, Colombo C, Smeraldi E (2005) Reality monitoring and paranoia in remitted delusional depression. Clinical Psychiatry, 2(3):199-205. 90. Zanardi R, Barbini B, Rossini D, Bernasconi A, Fregni F, Padberg F, Rossi S, Wirz-Justice A, Terman M, Martiny K, Bersani G, Hariri AR, Pezawas L, Roiser JP, Bertolino A, Calabrese G, Magri L, Benedetti F, Pontiggia A, Malaguti A, Smeraldi E, Colombo C (2008) New perspectives on techniques for the clinical psychiatrist: Brain stimulation, chronobiology and psychiatric brain imaging. Psychiatry and Clinical Neurosciences, 62(6):627-37. 91. Ruffini C, Locatelli M, Lucca A, Benedetti F, Insacco C, Smeraldi E (2009) Augmentation effect of repetitive transcranial magnetic stimulation over the orbitofrontal cortex in drugresistant obsessive-compulsive disorder patients: a controlled investigation. Primary care companion to the Journal of Clinical Psychiatry, 11(5):226-30. Books and Book Chapters 92. Moja EA, Benedetti F (1992) Somministrazione di miscele di aminoacidi prive di triptofano: una rassegna degli effetti biochimici e comportamentali. In: Nutrizione e cervello, a cura di LF Agnati, EA Moja e G Tettamanti; pp. 322-351. Pithagora Press, Milano. 93. Benedetti F, Colombo C, Sforzini L, Maffei C, Smeraldi E. (1999) New drugs in the treatment of borderline personality disorder. In: Treatment of personality disorders. A cura di J Derksen, C Maffei e H Grohen. Kluwer Academic / Plenum Publishers, New York, pag. 229240 94. Colombo C, Benedetti F, Barbini B, Smeraldi E (2000) Uso delle benzodiazepine nei disturbi dell’umore. In: Le benzodiazepine: dalla molecola alla pratica clinica. A cura di G Biggio. Springer-Verlag Italia, Milano, pp. 131-144. 95. Benedetti F (2005) Quattro motivi per morire: il suicidio come comportamento umano. Airon, Milano. [Four reasons to die: suicide as a human behaviour] 96. Wirz-Justice A, Benedetti F, Terman M (2009) Chronotherapeutics for affective disorders. A clinician’s manual for light and wake therapy. Karger, Basel. ISBN-13: 978-3-8055-9120-1 eISBN: 978-3-8055-9121-8 97. Dallaspezia S, Benedetti F. (2010) Genetics of circadian rhythms in relation to mental illness. In: Sleep and Mental Illness, M Kramer and SR Pandi Perumal eds. Cambridge University Press. ISBN-13: 9780521110501 98. Benedetti F (2010) Brain imaging funzionale della depressione. In: I disturbi dell'umore clinica e terapia, a cura di E. Smeraldi. Sintesi Infomedica, Milano. ISBN: 8887844135 ISBN-13: 9788887844139 14 Dr Francesco Benedetti Curriculum vitae 99. Benedetti F (2011) Sommeil et rythmes circadiens dans le troubles bipolaires à début précoce. In: M. Leboyer (ed.) Âge et mode de début des maladies psychiatriques : Perspective cliniques, étiologiques et thérapeutiques. Elsevier-Masson. ISBN: 978-2-29410803-7. p.33-46 Journal Articles, italian journals 100. Antonietti A, Benedetti F, Caselgrandi E, Moja EA (1991) Il consumo etilico spontaneo nel ratto in seguito a lunghi periodi di presentazione e deprivazione di alcool. Contributi di Psicologia, 1:95-104. 101. Rocchi E, Borghi A, Pradelli M, Paolillo F, Casalgrandi G, Benedetti F, Moja EA (1992) Implicazioni cliniche dell'utilizzo di una miscela aminoacidica priva di triptofano nella cirrosi epatica. Recenti Progressi in Medicina, 83:213-217. 102. Benedetti F, Moja EA (1992) Comportamento sessuale del ratto femmina in laboratorio: una rassegna delle tecniche di valutazione. Ricerche di Psicologia, XVI, 3:7-38. 103. Benedetti F, Barbini B, Colombo C (1997) Fluttuazioni infradiane dell’umore durante un episodio depressivo maggiore. [abstract] New Trends in Psichiatria, V, 2:12. 104. Zanardi R, Benedetti F (1998) Strategie alternative nel trattamento dei disturbi dello spettro depressivo. Bollettino di aggiornamento in Neuropsicofarmacologia, XIV, 68:1-2. 105. Colombo C, Benedetti F (1999) L'insonnia di Don Chisciotte. Deprivazione di sonno, neuroscienze e modelli epistemologici. Psichiatria e Psicoterapia Analitica, XVIII, 1: 18-21. 106. Benedetti F, Barbini B, Campori E, Cigala Fulgosi M, Colombo C, Smeraldi E (2001) Ritmi, sonno e disturbo bipolare. Psichiatri oggi, III, 1: 44-46. 107. Zanardi R, Serretti A, Rossini D, Benedetti F, Cusin C, Smeraldi E (2001) Strategie di potenziamento della terapia antidepressiva. Psichiatri oggi, III, 1: 49-50. 108. Bernasconi A, Benedetti F, Colombo C, Smeraldi E. (2003) Luci sulla depressione. Kos 219:44-51. 15 Dr Francesco Benedetti Curriculum vitae Journal Abstracts, peer reviewed (proceedings) A. Clinical chronotherapeutics of mood disorders 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. Barbini B, Benedetti F, Campori E, Guglielmo E, Colombo C, Smeraldi E. (1995) Perceived symptomatology and biological rhythms in unipolar patients. World Conference on Chronobiology and Chronotherapeutics. Biological Rhythms Research, 26:365. Barbini B, Colombo C, Benedetti F, Campori E, Di Molfetta D, Smeraldi E. (1995) The study of circadian and infradian fluctuations in mood disorders: a methodological approach. World Conference on Chronobiology and Chronotherapeutics. Biological Rhythms Research, 26:365-366. Barbini B, Benedetti F, Campori E, Colombo C, Smeraldi E. (1997) Differential effect of total sleep deprivation in unipolar and bipolar depression. 6th World Congress of Biological Psychiatry; 1997 Jun 22-27; Nice. Biological Psychiatry 42 (Suppl 1):109S. Benedetti F, Barbini B, Campori E, Colombo C, Smeraldi E. (1997) Patterns of infradian mood variation in major depression. 6th World Congress of Biological Psychiatry; 1997 Jun 22-27; Nice. Biological Psychiatry 42 (Suppl 1):109S. Barbini B, Benedetti F, Campori E, Colombo C, Smeraldi E. (1997) Circadian mood fluctuation as a predictor of th the antidepressant response to total sleep deprivation. 6 World Congress of Biological Psychiatry; 1997 Jun 22-27; Nice. Biological Psychiatry 42(Suppl 1):233S. Benedetti F, Colombo C, Barbini B, Lucca A, Campori E, Cigala Fulgosi M, Smeraldi E (2001) Light and lithium th to sustain the rapid effects of total sleep deprivation in bipolar depression. 6 Regional Meeting of the European College of Neuropsychopharmacology. Napoli, 2001 May 19-21. European Neuropsychopharmacology, 11(Suppl. 2):S52 Benedetti F, Cigala Fulgosi M, Colombo C, Barbini B, Campori E, Smeraldi E (2001) Availability of morning th sunlight and response to antidepressant treatments. 6 Regional Meeting of the European College of Neuropsychopharmacology. Napoli, 2001 May 19-21. European Neuropsychopharmacology, 11(Suppl. 2):S51 Colombo C, Benedetti F, Barbini B, Campori E, Cigala Fulgosi M (2001) Light, lithium and sleep phase advance th to sustain the rapid effects of total sleep deprivation in bipolar depression. 7 World Congress of Biological Psychiatry. Berlin, 2001 July 1-6. The World Journal of Biological Psychiatry, 2(Suppl.1):352S Benedetti F (2001) Light treatment effects in bipolar disorder. Society for Light Treatment and Biological th Rhythms, 13 Annual Meeting. Stockholm, 2001 June 24-27. Stress Research Reports, 297:50. Benedetti F, Colombo C, Barbini B, Smeraldi E (2002) Sleep deprivation and biological rhythms in bipolar disorder. 1st Biennal Conference of the International Society for Affective Disorders. Taormina, March 9-12. Journal of Affective Disorders 68 (1): 88-89. Benedetti F, Colombo C, Pontiggia A, Bernasconi A, Barbini B, Smeraldi E (2003) Chronobiological treatment th of bipolar depression. 16 Congress of the European College of Neuropsychopharmacology, Praga, September 20-24. European Neuropsychopharmacology 13(Suppl. 4) :S108. Bernasconi A, Benedetti F, Colombo C, Pontiggia A, Florita M, Smeraldi E (2003) Morning light therapy as an th augmenting strategy of antidepressant treatment. 16 Congress of the European College of Neuropsychopharmacology, Praga, September 20-24. European Neuropsychopharmacology13(Suppl. 4) : S224. Pontiggia A, Benedetti F, Bernasconi A, Florita M, Colombo C, Cropanese I, Smeraldi E (2003) Phase-response th effects of lormetazepam in depressive insomnia. 16 Congress of the European College of Neuropsychopharmacology, Praga, September 20-24. European Neuropsychopharmacology13(Suppl. 4) : S223. Benedetti F, Colombo C, Bernasconi A, Barbini B, Cigala Fulgosi M, Pontiggia A, Smeraldi E (2004) Chronobiological treatments of bipolar depression. The International Society for Affective Disorders (ISAD)– 2nd Biennial Conference–Cancun, Mexico 5th–10th March 2004. Journal of Affective Disorders 78(Suppl.1): S14. Bernasconi A, Benedetti F, Colombo C, Pontiggia A, Florita M, Smeraldi E (2004) Light therapy in the morning: augmenting strategy of antidepressant treatment. World Psychiatric Association International Congress “Treatments in Psychiatry: an update”. Firenze, November 10-13. World Psychiatry 3(Suppl. 1):265. Pontiggia A, Benedetti F, Bernasconi A, Colombo C, Florita M, Dallaspezia S (2004) Phase response effet of lormetazepam in the treatment of depressive insomnia. World Psychiatric Association International Congress “Treatments in Psychiatry: an update”. Firenze, November 10-13. World Psychiatry 3(Suppl. 1):280. 16 Dr Francesco Benedetti Curriculum vitae 17. Benedetti F, Barbini B, Bernasconi A, Cigala Fulgosi M, Colombo C, Dallaspezia S, Pontiggia A, Smeraldi E (2005) The role of brain monoamines in the antidepressant response to sleep deprivation. XIII congress of the Association of European Psychiatrists. Munich, Germany, April 2-6. European Psychiatry, 20(Suppl 1):S112. th 18. Benedetti F (2005) Chronobiological treatments of bipolar illness. 8 World Congress of Biological Psychiatry. th rd Vienna, Austria, June 28 – July 3 . World Journal of Biological Psychiatry, 6(Suppl 1):S16. 19. Cigala Fulgosi M, Pontiggia A, Bernasconi A, Dallaspezia S, Colombo C, Barbini B, Benedetti F (2005). Is sleep th deprivation useful in the treatment of resistant bipolar depression? 8 World Congress of Biological th rd Psychiatry. Vienna, Austria, June 28 – July 3 . World Journal of Biological Psychiatry, 6(Suppl 1):S166. 20. Pontiggia A, Benedetti F, Barbini B, Cigala Fulgosi M, Colombo C, Dallaspezia S, Smeraldi E (2006) Long term outcome of drug-resistant bipolar depression: a 9 months prospective follow-up after chronotherapeutics. ECNP Workshop on Neuropsychopharmacology for young scientists in Europe. Nice, France, March 9-12. European Neuropsychopharmacology, 16(Suppl 1):S72-73. 21. Benedetti F (2006) Sleep deprivation and light therapy. 19th congress of the European College of Neuropsychopharmacology, Paris 16-20 September. European Neuropsychopharmacology, 16 (Suppl 4):S190. 22. Pontiggia A, Benedetti F, Barbini B, Cigala Fulgosi M, Colombo C, Dallaspezia S, Smeraldi E (2006). An actigraphic registration of depressed patients treated with chronotherapeutics. 19th congress of the European College of Neuropsychopharmacology, Paris 16-20 September. European Neuropsychopharmacology, 16 (Suppl 4):S293. 23. Benedetti F (2006) Circadian rhythms and mood disorders: chronotherapeutic implications. 8th World Congress of Psycho-Oncology, Venezia 16-21 October. Psycho-Oncology, 15(2 Suppl):58-59. 24. Benedetti F (2007) Sleep deprivation: a forgotten tool? 7th International Forum on Mood & Anxiety Disorders - Budapest 5-7 December. International Journal of Psychiatry in Clinical Practice, 11(4):303. 25. Benedetti F, Cigala Fulgosi M, Gavinelli C, Barbini B, Colombo C, Smeraldi E (2007) Homeostatic and allostatic response to sleep deprivation in bipolar depression. 7th International Forum on Mood & Anxiety Disorders Budapest 5-7 December. International Journal of Psychiatry in Clinical Practice, 11(4):316. 26. Benedetti F, Fresi F, Maccioni P, Smeraldi E (2008) Manic-like reaction to sleep deprivation in mice follows a cyclical pattern and a dose-response effect. 3rd Biennial Conference of the International Society for Bipolar Disorders, New Dehli-Agra 27-30 January. Bipolar Disorders, 10(Suppl.1):39. 27. Benedetti F, Cigala Fulgosi M, Gavinelli C, Lietti L, Dallaspezia S, Barbini B, ColomboC, Smeraldi E (2008) Lower need of homeostatic sleep after successful sleep deprivation therapy of depression. 3rd Biennial Conference of the International Society for Bipolar Disorders, New Dehli-Agra 27-30 January. Bipolar Disorders, 10(Suppl.1):70. 28. Benedetti F. The neurobiology of antidepressant response to sleep deprivation. 3rd Biennial Conference of the International Society for Bipolar Disorders, New Dehli-Agra 27-30 January. Bipolar Disorders, 10(Suppl.1):17. 29. Benedetti F, Cigala Fulgosi M, Gavinelli C, Barbini B, ColomboC, Smeraldi E (2008) Homeostatic and allostatic response to sleep deprivation in bipolar depression. XXVI Congress of the Collegium Internationale NeuroPsychopharmacologicum (CINP), Munich 13-17 July. International Journal of Neuropsychopharmacology, 11(Suppl 1):114. 30. Benedetti F, Fresi F, Maccioni P, Smeraldi E (2008) Manic-like reaction to sleep deprivation in mice follows a cyclical pattern and a dose-response effect. XXVI Congress of the Collegium Internationale NeuroPsychopharmacologicum (CINP), Munich 13-17 July. International Journal of Neuropsychopharmacology, 11(Suppl 1):121. 31. Benedetti F (2009) Chronotherapeutics to treat bipolar depression in a psychiatric ward. World Psychiatric Association (WPA) International Congress, Firenze, 1-4 April. World Psychiatry 8(Suppl 1): 64 32. Benedetti F, Colombo C (2009) The clinical usefulness of chronotherapeutics for bipolar disorder: rationale and perspectives. Eighth International Conference on Bipolar Disorder, 25-27 June, Pittsburgh. Bipolar Disorders, 11(Suppl. 1): 33. Benedetti F (2011) Neuroimaging and genetics of sleep deprivation in depression: from monoamines and glutamate to neuroplasticity. Worldsleep2011: New Horizons Of Sleep Research For Our Planet. Kyoto, 16–20 October. Sleep and Biological Rhythms 2011; 9:209-210. 34. Benedetti F (2011) Glutamatergic Neurotransmission and Synaptic Homeostasis in the Rapid Antidepressant Effect of Sleep Deprivation. American College of Neuropsychopharmacology (ACNP) 50th Annual Meeting, Waikoloa, December 4-8. Neuropsychopharmacology 36:S16. 17 Dr Francesco Benedetti Curriculum vitae B. Psychiatric genetics 35. Benedetti F, Colombo C, Barbini B, Campori E, Cigala Fulgosi M, Serretti A. (2000) Genetic differences in th antidepressant response to sleep deprivation. 8 World Congress on Psychiatric Genetics, Versailles, 27-31 August 2000. American Journal of Medical Genetics 96(4):537. 36. Zanardi R, Benedetti F, Serretti A, Smeraldi E. (2000) Genetic influence on response to serotonergic th antidepressants. 8 World Congress on Psychiatric Genetics, Versailles, 27-31 August 2000. American Journal of Medical Genetics 96(4):538. 37. Benedetti F, Colombo C, Barbini B, Campori E, Cigala Fulgosi M, Serretti A, Smeraldi E (2001) Genetic th predictors of antidepressant response to total sleep deprivation. 6 Regional Meeting of the European College of Neuropsychopharmacology. Napoli, 2001 May 19-21. European Neuropsychopharmacology, 11(Suppl. 2):S38 th 38. Zanardi R, Benedetti F, Serretti A, Smeraldi E (2001) Genetic predictors of response to SSRIs. 6 Regional Meeting of the European College of Neuropsychopharmacology. Napoli, 2001 May 19-21. European Neuropsychopharmacology, 11(Suppl. 2):S38 39. Colombo C, Benedetti F, Barbini B, Cigala Fulgosi M, Campori E (2001) Genetic predictors of antidepressant th response to total sleep deprivation. 7 World Congress of Biological Psychiatry. Berlin, 2001 July 1-6. The World Journal of Biological Psychiatry, 2(Suppl.1):214S 40. Benedetti F, Colombo C, Barbini B, Campori E, Cigala Fulgosi M, Smeraldi E (2002) Genetic predictors of th antidepressant response to sleep deprivation. 14 Congress of the European College of Neuropsychopharmacology, Istanbul, October 13-17. European Neuropsychopharmacology, 11 (Suppl. 3), S243. 41. Serretti A, Cusin C, Lorenzi C, Benedetti F, Pirovano A, Arnoldi A, Zanardi R, Colombo C, Smeraldi E (2003) Genetic predictors of antidepressants efficacy: the state of the art. The XIth World Congress of Psychiatric Genetics. Quebec, 15/09/2003. Vol. American Journal of Medical Genetics, 122B:36. 42. Benedetti F, Serretti A, Cusin C, Mandelli L, Pirovano A, Zanardi R, Colombo C, Smeraldi E (2003) CLOCK gene th influences insomnia during antidepressant treatment. 16 Congress of the European College of Neuropsychopharmacology, Praga, September 20-24. European Neuropsychopharmacology13(Suppl. 4) : S226. 43. Serretti A, Lorenzi C, Benedetti F, Pirovano A, Zanardi R, Colombo C, Ploia C, Tubazio V, Smeraldi E (2004) Genetic polymorphisms influencing response of antidepressants. XXIV CINP Congress. Paris, 20-24 June. International Journal of Neuropsychopharmacology, 7(Suppl.1):S67. 44. Serretti A, Lorenzi C, Benedetti F, Pirovano A, Zanardi R, Colombo C, Ploia C, Tubazio V, Smeraldi E (2004) Genetic predictors of antidepressants efficacy: The State of the Art. European Psychiatry, 19(Suppl.1):79S79S. 45. Pontiggia A, Bernasconi A, Benedetti F, Serretti A, Lorenzi C, Colombo C, Smeraldi E. (2005) A glycogen synthase kinase 3-β -50 T/C SNP influences long-term response to lithium salts in bipolar illness. ECNP Workshop on Neuropsychopharmacology for young scientists in Europe. Nice, France, March 3-6. European Neuropsychopharmacology, 15(Suppl 1):S56-S57. 46. Pontiggia A, Benedetti F, Bernasconi A, Colombo C, Lorenzi C, Serretti A, Smeraldi E (2005) GSK3B and the th molecular clock as novel targets in the treatment of bipolar disorder. 8 World Congress of Biological th rd Psychiatry. Vienna, Austria, June 28 – July 3 . World Journal of Biological Psychiatry, 6(Suppl 1):S160. th 47. Benedetti F. (2005) The molecular clock as a target in the treatment of bipolar disorder. 44 Annual Meeting of the American College of Neuropsychopharmacology. Waikoloa, Hawaii, 11-15 December. Neuropsychopharmacology, 30(Suppl. 1): S63-S64. 98. 48. M. Bosia, R. Cavallaro, F. Benedetti, G. Guerriero, F. Cocchi, E. Marino, E. Smeraldi (2007) Association study of GSK-3β -50T/C polymorphism with haloperidol resistance in schizophrenia. ECNP Workshop on Neuropsychopharmacology for young scientists in Europe. Nice, France, March 8-11. European Neuropsychopharmacology, 17(Suppl. 1):S77 49. Dallaspezia S, Benedetti F, Colombo C, Barbini B, Smeraldi E (2007) Lithium therapy reverses the influence of 5-HTTLPR gene polymorphism on anti-depressant response to sleep deprivation. . ECNP Workshop on Neuropsychopharmacology for young scientists in Europe. Nice, France, March 8-11. European Neuropsychopharmacology, 17(Suppl. 1):S79 50. Benedetti F, Lietti L, Barbini B, Lorenzi C, Marino E, Cigala Fulgosi M, Pontiggia A, Dallaspezia S, Colombo C, Smeraldi E (2007) CLOCK gene polymorphism rs1801260 biases response to light treatment after sleep deprivation. International Journal of Psychiatry in Clinical Practice, 11(4):316. 51. Benedetti F, Lietti L, Barbini B, Cigala Fulgosi M, Dallaspezia S, Lorenzi C, Pirovano A, Pontiggia A, Colombo C, Smeraldi E (2008) Response to light treatment after sleep deprivation is influenced by CLOCK 3111 T/C SNP 18 Dr Francesco Benedetti Curriculum vitae (rs1801260) gene polymorphism. 3rd Biennial Conference of the International Society for Bipolar Disorders, New Dehli-Agra 27-30 January. Bipolar Disorders, 10(Suppl.1):70. 52. Benedetti F, Barbini B, Lorenzi C, Lietti L, Marino E, Cigala Fulgosi M, Pontiggia A, Dallaspezia S, Colombo C, Smeraldi E (2008) Clock gene polymorphism rs1801260 biases response to light treatment after sleep deprivation. XXVI Congress of the Collegium Internationale Neuro-Psychopharmacologicum (CINP), Munich 13-17 July. International Journal of Neuropsychopharmacology, 11(Suppl 1): , 11(Suppl 1):106. 53. Benedetti F (2008) Pharmacogenetics of human therapeutic response to lithium and other therapeutic interventions. XXVI Congress of the Collegium Internationale Neuro-Psychopharmacologicum (CINP), Munich 13-17 July. International Journal of Neuropsychopharmacology, 11(Suppl 1):50. 54. Benedetti F (2009) Influence of gene variants affecting the Clock on psychopathology and response to treatment in bipolar disorder. Eighth International Conference on Bipolar Disorder, 25-27 June, Pittsburgh. Bipolar Disorders, 11 (Suppl. 1):1. C. Brain Imaging and genetic correlates of psychiatric diseases and therapeutics 55. Benedetti F, Bernasconi A, Lorenzi C, Pontiggia A, Serretti A, Colombo C, Smeraldi E (2003) Glycogen synthase kinase 3-B influences age at onset of bipolar disorder. XIth World Congress of Psychiatric Genetics. Quebec, 15/09/2003 American Journal of Medical Genetics, 122B:113. 56. Lorenzi C, Serretti A, Benedetti F, Tubazio V, Ploia C, Colombo C, De Ronchi D, Smeraldi E (2003) Human PERIOD 3 gene influences SSRIs antidepressant activity in mood disorders. The XIth World Congress of Psychiatric Genetics. Quebec, 15/09/2003. American Journal of Medical Genetics, 122B:124. pp. 57. Mandelli L, Serretti A, Benedetti F, Lorenzi C, Pirovano A, Colombo C, Smeraldi E (2003) Genetic dissection of psychopathological symptoms: insomnia in mood disorders and CLOCK gene polymorphism. The XIth World Congress of Psychiatric Genetics. Quebec, 15/09/2003. American Journal of Medical Genetics, 122B:67. 58. Benedetti F, Serretti A, Colombo C, Barbini B, Lorenzi C, Campori E, Smeraldi E (2003) CLOCK gene and th circadian mood fluctuations in bipolar depression. 16 Congress of the European College of Neuropsychopharmacology, Praga, September 20-24. European Neuropsychopharmacology 13(Suppl. 4) :S223 59. Benedetti F, Serretti A, Mandelli L, Lorenzi C, Pirovano A, Colombo C, Smeraldi E (2003) Genetic dissection of th psychopathological symptoms: insomnia in mood disorders and CLOCK gene polymorphism. 16 Congress of the European College of Neuropsychopharmacology, Praga, September 20-24. European Neuropsychopharmacology13(Suppl. 4) :S225 60. Benedetti F, Bernasconi A, Lorenzi C, Pontiggia A, Colombo C, Smeraldi E (2003) Glycogen synthase-kinase 3β th influences age at onset of bipolar disorder. 16 Congress of the European College of Neuropsychopharmacology, Praga, September 20-24. European Neuropsychopharmacology 13(Suppl. 4) : S225 61. Massa R, Serretti A, Benedetti F, Artioli P, Mandelli L, Ploia C, Pirovano A, Smeraldi E (2004) Insomnia and mood diurnal variations in mood disorder patients: the involvement of CLOCK and PER3 genes. XIIth World Congress of Psychiatric Genetics. Dublin, Ireland, 9th–13th October 2004. American Journal of Medical Genetics, 130B:33. 62. Ploia C, Serretti A, Benedetti F, Fontana V, Colombo C, Catalano M, Smeraldi E (2004) Mood disorders and antidepressants treatment: haplotype analysis of human PERIOD 3 gene. XIIth World Congress of Psychiatric Genetics. Dublin, Ireland, 9th–13th October 2004. American Journal of Medical Genetics, 130B:160. 63. Tubazio V, Benedetti F, Serretti A, Ploia C, Pirovano A, Smeraldi E (2004) Glicogen synthase kinase (GSK) gene promoter polymorphisms: a tdt and haplotype approach in mood disorders. XIIth World Congress of Psychiatric Genetics, Dublin, Ireland, 9th–13th October 2004. American Journal of Medical Genetics 130B:37. 64. Serretti A, Artioli P, Mandelli L, Lorenzi C, Benedetti F, Smeraldi E (2004) How do genes exert their role? PER3 variants and possible influences on mood disorder phenotypes. XIIth World Congress of Psychiatric Genetics. Dublin, Ireland, 9th–13th October 2004. American Journal of Medical Genetics 130B:117. 65. Bernasconi A, Radaelli D, Benedetti F, Blasi V, Cadioli M, Colombo C, Falini A, Scotti G, Smeraldi E (2005) Recovery from bipolar depression after total sleep deprivation: a 3.0 T BOLD fMRI event-related study of moral thinking. ECNP Workshop on Neuropsychopharmacology for young scientists in Europe. Nice, France, March 3-6. European Neuropsychopharmacology, 15(Suppl 1):S61. 66. Radaelli D, Bernasconi A, Benedetti F, Blasi V, Cadioli M, Colombo C, Falini A, Scotti G, Smeraldi E (2005) Neural correlates of distorted moral thinking in bipolar depression: a 3.0 T BOLD fMRI event-related study. ECNP Workshop on Neuropsychopharmacology for young scientists in Europe. Nice, France, March 3-6. European Neuropsychopharmacology, 15(Suppl 1):S63. 19 Dr Francesco Benedetti Curriculum vitae 67. Radaelli D, Bernasconi A, Benedetti F, Blasi V, Cadioli M, Colombo C, Falini A, Scotti G, Smeraldi E (2005) th Changes in right DLPFC (BA9) after treatment in bipolar depression. 8 World Congress of Biological th rd Psychiatry. Vienna, Austria, June 28 – July 3 . World Journal of Biological Psychiatry, 6(Suppl 1):S160-161. 68. Bernasconi A, Radaelli D, Benedetti F, Blasi V, Cadioli M, Colombo C, Falini A, Scotti G, Smeraldi E (2005) th Moral thinking and depression: a 3.0T BOLD fMRI event-related study. 8 World Congress of Biological th rd Psychiatry. Vienna, Austria, June 28 – July 3 . World Journal of Biological Psychiatry, 6(Suppl 1):S194. 69. Bernasconi A, Calabrese G, Benedetti F, Radaelli D, Dallaspezia S, Falini A, Colombo C, Cadioli M, Scotti G, Smeraldi E (2006) Changes in brain glutamate correlate with antidepressant response to total sleep deprivation: a 3T 1H-MRS study. ECNP Workshop on Neuropsychopharmacology for young scientists in Europe. Nice, France, March 9-12. European Neuropsychopharmacology, 16(Suppl 1):S69. 70. Dallaspezia S, Benedetti F, Bernasconi A, Blasi V, Colombo C, Falini A, Radaelli D, Scotti G, Smeraldi E (2006) Influence of brain activity at the baseline on antidepressant response to chronotherapeutic treatment: a fMRI study. ECNP Workshop on Neuropsychopharmacology for young scientists in Europe. Nice, France, March 912. European Neuropsychopharmacology, 16(Suppl 1):S70. 71. Radaelli D, Bernasconi A, Benedetti F, Blasi V, Colombo C, Falini A, Scotti G, Smeraldi E (2006) Influence of serotonin transporter promoter polymorphism on brain activation during a moral valence decision task. ECNP Workshop on Neuropsychopharmacology for young scientists in Europe. Nice, France, March 9-12. European Neuropsychopharmacology, 16(Suppl 1):S70-71. 72. Bernasconi A, Benedetti F, Blasi V, Cadioli M, Colombo C, Dallaspezia S, Falini A, Radaelli D, Scotti G (2006) A 3 T BOLD functional MRI study of the neural underpinnings of depression. European Neuropsychopharmacology, 16 (Suppl 4):S273. 73. Dallaspezia S, Benedetti F, Cigala Fulgosi M, Barbini B, Colombo C, Lorenzi C, Serretti A, Smeraldi E (2006) Influence of CLOCK gene polymorphism on sleep-wake cycle in depressed bipolar patients: an actigraphic study. European Neuropsychopharmacology, 16 (Suppl 4):S361. 74. Radaelli D, Benedetti F, Bernasconi A, Blasi V, Cadioli M, Colombo C, Dallaspezia S, Falini A, Scotti G, Smeraldi E (2006) Neural correlates of emotional self in bipolar disorder: a BOLD functional MRI 3 T study. European Neuropsychopharmacology, 16 (Suppl 4):S270. 75. Marino E, Lorenzi C, Pirovano A, Benedetti F, Catalano M, Smeraldi E (2007) How do genes exert their role? Period 3 gene variants and possible influences on mood disorder phenotypes. ECNP Workshop on Neuropsychopharmacology for young scientists in Europe. Nice, France, March 8-11. European Neuropsychopharmacology, 17(Suppl. 1):S4 76. Poletti S, Benedetti F, Bosia M, Pirovano A, Cocchi F, Smeraldi E (2007) Association study of GSK-3β -50T/C polymorphism with executive performances in schizophrenia. ECNP Workshop on Neuropsychopharmacology for young scientists in Europe. Nice, France, March 8-11. European Neuropsychopharmacology, 17(Suppl. 1):S79. 77. Radaelli D, Bernasconi A, Benedetti F, Colombo C, Falini A, Scotti G, Smeraldi E (2007) Clock genotype biases neural correlates of moral valence decision in patients affected by bipolar depression. ECNP Workshop on Neuropsychopharmacology for young scientists in Europe. Nice, France, March 8-11. European Neuropsychopharmacology, 17(Suppl. 1):S73 78. Radaelli D, Bernasconi A, Dallaspezia S, Poletti S, Benedetti F, Falini A, Colombo C (2007) Stressful life events bias neural correlates of moral valence decision in patients affected by mood disorder. 20th congress of the European College of Neuropsychopharmacology, Wien 13-17 October. European Neuropsychopharmacology, 17(Suppl. 4):S292. 79. Poletti, D. Radaelli, S. Dallaspezia, A. Bernasconi, F. Benedetti, A. Falini, R. Cavallaro (2007) Neural correlates of emotional processing in schizophrenia: an fMRI study. 20th congress of the European College of Neuropsychopharmacology, Wien 13-17 October. European Neuropsychopharmacology, 17(Suppl. 4):S287. 80. Benedetti F, Radaelli D, Bernasconi A, Dallaspezia S, Unterhofer V, Colombo C, Falini A, Scotti G, Smeraldi E (2007) Stressful life events bias neural correlates of emotional processing in bipolar disorder. 7th International Forum on Mood & Anxiety Disorders - Budapest 5-7 December. International Journal of Psychiatry in Clinical Practice, in press. 81. Benedetti F, Dallaspezia S, Lorenzi C, Pirovano A, Colombo C, Smeraldi E (2007) A VNTR polymorphism in hPER3 gene influences clinical characteristic of bipolar disorder. 7th International Forum on Mood & Anxiety Disorders - Budapest 5-7 December. International Journal of Psychiatry in Clinical Practice, 11(4):317. 82. Benedetti F, Poletti S, Radaelli D, Dallaspezia S, Bernasconi A, Colombo C, Cavallaro R, Falini A, Scotti G, Smeraldi E (2007) Bipolar disorder and schizophrenia influence neural responses in amygdala and anterior cyngulate to emotional faces. 7th International Forum on Mood & Anxiety Disorders - Budapest 5-7 December. International Journal of Psychiatry in Clinical Practice, 11(4):317. 20 Dr Francesco Benedetti Curriculum vitae 83. Benedetti F, Dallaspezia S, Colombo C, Smeraldi E. Period gene 3 polymorphism influences clinical characteristics of bipolar disorder. 3rd Biennial Conference of the International Society for Bipolar Disorders, New Dehli-Agra 27-30 January. Bipolar disorders, 10(Suppl.1):69. 84. Benedetti F, Poletti S, Radaelli D, Dallaspezia S, Bernasconi A, Colombo C, Cavallaro R, Falini A, Scotti G, Smeraldi E (2008) Amygdala and the anterior cyngulate in the emotional processing in bipolar disorder and schizophrenia. a 3.0 tesla BOLD fMRI study. 3rd Biennial Conference of the International Society for Bipolar Disorders, New Dehli-Agra 27-30 January. Bipolar disorders, 10(Suppl.1):70. 85. Benedetti F, Radaelli D, Unterhofer V, Bernasconi A, Dallaspezia S, Colombo C, Falini A, Scotti G, Smeraldi E (2008) Stressful life events bias neural correlates of emotional processing in bipolar disorder. 3rd Biennial Conference of the International Society for Bipolar Disorders, New Dehli-Agra 27-30 January. Bipolar disorders, 10(Suppl.1):70-71. 86. Benedetti F, Radaelli D, Bernasconi A, Dallaspezia S, Falini A, Colombo C, Scotti G, Smeraldi E (2008) Personality disorder and depression: a fMRI study. XXVI Congress of the Collegium Internationale NeuroPsychopharmacologicum (CINP), Munich 13-17 July. International Journal of Neuropsychopharmacology, 11(Suppl 1):98. 87. Benedetti F, Bernasconi A, Calabrese G, Radaelli D, Dallaspezia S, Cadioli M, Colombo C, Falini A, Scotti G, Smeraldi E (2008) Changes in brain glutamate correlate with antidepressant response to total sleep deprivation in bipolare depression: An high-field 1H-MRS study. XXVI Congress of the Collegium Internationale Neuro-Psychopharmacologicum (CINP), Munich 13-17 July. International Journal of Neuropsychopharmacology, 11(Suppl 1):97. 88. Benedetti F, Bernasconi A, Radaelli D, Dallaspezia S, Falini A, Colombo C, Scotti G, Smeraldi E (2008) Changes in medial prefrontal cortex neural responses parallel successful antidepressant combination of venlafaxine and light therapy. XXVI Congress of the Collegium Internationale Neuro-Psychopharmacologicum (CINP), Munich 13-17 July. International Journal of Neuropsychopharmacology, 11(Suppl 1):97. 89. Benedetti F, Dallaspezia S, Lorenzi C, Pirovano A, Colombo C, Smeraldi E. (2008) A VNTR polymorphism in hPER3 gene influences clinical characteristic of bipolar disorder. XXVI Congress of the Collegium Internationale Neuro-Psychopharmacologicum (CINP), Munich 13-17 July. International Journal of Neuropsychopharmacology, 11(Suppl 1):106. 90. Benedetti F, Radaelli D, Bernasconi A, Dallaspezia S, Poletti S, Giannunzio V, Colombo C, Falini A, Scotti G, Smeraldi E (2008) Stressful life events bias neural correlates of task targeting the depressive biases in information processing in patients affected by mood disorder. XXVI Congress of the Collegium Internationale Neuro-Psychopharmacologicum (CINP), Munich 13-17 July. International Journal of Neuropsychopharmacology, 11(Suppl 1):98. 91. Benedetti F, Poletti S, Riccaboni R, Cavallaro R, Falini A, Scotti G, Smeraldi E (2008) Neural correlates of theory of mind and empathy in schizophrenic patients and healthy controls: A functional magnetic resonance imaging study. XXVI Congress of the Collegium Internationale Neuro-Psychopharmacologicum (CINP), Munich 13-17 July. International Journal of Neuropsychopharmacology, 11(Suppl 1):248. 92. Benedetti F, Poletti S, Radaelli D, Dallaspezia S, Bernasconi A, Giannunzio V, Colombo C, Cavallaro R, Falini A, Scotti G, Smeraldi E (2008) Amygdala and the anterior cingulate in the emotional processing in bipolar disorder and schizophrenia. A 3.0 tesla BOLD fMRI study. XXVI Congress of the Collegium Internationale Neuro-Psychopharmacologicum (CINP), Munich 13-17 July. International Journal of Neuropsychopharmacology, 11(Suppl 1):269. 93. Benedetti F (2009) Disruption of white matter integrity in bipolar disorder: tract-specific analyses of the th cortico-limbic network and voxelwise study of the white matter skeleton. 10 Psychoimmunology Expert Meeting, Gunzburg, November 12-14. Neurology, Psychiatry and Brain Research 16(Suppl 1): 7. 94. Benedetti F (2010) Neuroimaging and genetics of antidepressant response. 65th annual meeting of the Society of Biological Psychiatry, New Orleans May 20-22. Biological Psychiatry, 67(Suppl 9)103S-104S. 95. Benedetti F (2011) Neuroimaging and genetics of antidepressant response to sleep deprivation: implications for drug development. 19th European Congress of Psychiatry, Vienna, 12-15 March 2011. European Psychiatry, 26(Suppl 1)S06-2. 96. Giacosa C, Radaelli D, Poletti S, Smeraldi E, Benedetti F (2011) White matter diffusivity changes in obsessivecompulsive disorder: a diffusion tensor MRI study with tract-based spatial statistics. European Neuropsychopharmacology, 97. Benedetti F (2011) The influence of adverse childhood experiences on brain structure and function in adult psychiatric conditions. 51th International Neuropsychiatric Pula Congress, Pula June 15-18. Acta Clinica Croatica, 50(Suppl.2):8. 21 Dr Francesco Benedetti Curriculum vitae D. Others 98. Moja EA, Benedetti F (1992) Pharmacological effects after a tryptophan-free mixture in normal and cirrhotic subjects. In: Advances in Tryptophan Research 1992, pp. 21-23; Fujita Health University Press, Toyoake 99. Colombo C, Benedetti F, Smeraldi E. (1997) Clozapine treatment of borderline personality disorder. 6th World Congress of Biological Psychiatry; 1997 Jun 22-27; Nice. Biological Psychiatry 42 (Suppl 1):31S. 100. Benedetti F, Cigala Fulgosi M, Colombo C, Barbini B, Pontiggia A, Carbonato I, Smeraldi E (2001) Rapid th assessment of cognitive distorsions in major depression. 6 Regional Meeting of the European College of Neuropsychopharmacology. Napoli, 2001 May 19-21. European Neuropsychopharmacology, 11(Suppl. 2):S51 101. Colombo C, Benedetti F, Cigala Fulgosi M, Smeraldi E (2001) Rapid assessment of cognitive distorsions in th major depression. 7 World Congress of Biological Psychiatry. Berlin, 2001 July 1-6. The World Journal of Biological Psychiatry, 2(Suppl.1):232S 102. Cigala Fulgosi M, Benedetti F, Florita M, Colombo C, Barbini B, Smeraldi E (2003) Rapid assessment of th cognitive distorsions in major depression. 16 Congress of the European College of Neuropsychopharmacology, Praga, September 20-24. European Neuropsychopharmacology 13(Suppl. 4) : S225. 103. Florita M, Benedetti F, Colombo C, Bernasconi A, Pontiggia A, Cigala Fulgosi M, Barbini B, Smeraldi E (2004) Neuropsychological functioning during antidepressant treatment in depressed patients. World Psychiatric Association International Congress “Treatments in Psychiatry: an update”. Firenze, November 10-13. World Psychiatry 3(Suppl. 1):263. 104. Cigala Fulgosi M, Benedetti F, Florita M, Colombo C, Barbini B, Smeraldi E (2004) Rapid assessment of cognitive distorsions in major depression. World Psychiatric Association International Congress “Treatments in Psychiatry: an update”. Firenze, November 10-13. World Psychiatry 3(Suppl. 1):264. 105. Radaelli D, Benedetti F, Anselmetti S, Florita M, Sartorio E, Cavallaro R, Colombo C, Smeraldi E (2004) Reality monitoring and paranoia in remitted delusional depression. World Psychiatric Association International Congress “Treatments in Psychiatry: an update”. Firenze, November 10-13. World Psychiatry 3(Suppl. 1):264. 106. Santoro A, Florita M, Benedetti F, Lucca A, Colombo C, Smeraldi E (2004) Transcranial magnetic stimulation modifies the processing of emotional stimuli in subjects with a major depressive episode. World Psychiatric Association International Congress “Treatments in Psychiatry: an update”. Firenze, November 10-13. World Psychiatry 3(Suppl. 1):266. 107. Florita M, Benedetti F, Colombo C, Bernasconi A, Pontiggia A, Cigala Fulgosi M, Barbini B, Smeraldi E (2003) th Changes in depressive neuropsychological functioning during antidepressant treatment. 16 Congress of the European College of Neuropsychopharmacology, Praga, September 20-24. European Neuropsychopharmacology13(Suppl. 4) : S224. 108. Santoro A, Florita M, Benedetti F, Rossini D, Lucca A (2004) rTMS is able to acutely modify the processing of emotionally characterized stimuli in subjects with a major depression episode. XXIV CINP Congress. Paris, 2024 June. International Journal of Neuropsychopharmacology, 7(Suppl.1):S473. 109. Anselmetti S, Cavallaro R, Benedetti F, Bechi M, Cocchi F, Ermoli E, Smeraldi E (2004) Source monitoring deficits in schizophrenia: A signal detection analysis study. Schizophrenia Research 67(Suppl.1):S266-S267. 110. Benedetti F, Radaelli D, Anselmetti S, Cavallaro R, Colombo C, Smeraldi E (2008) Reality monitoring deficits as common neuropsychological correlates of schizophrenic and affective psychosis. XXVI Congress of the Collegium Internationale Neuro-Psychopharmacologicum (CINP), Munich 13-17 July. International Journal of Neuropsychopharmacology, 11(Suppl 1):270. 111. Benedetti F (2009) An updated anatomy of melancholy: uncertain neural boundaries between thinking and feeling. 49th International Neuropsychiatric Pula Congress. Pula June 17-20. Acta Neuropsichiatrica, 21(S 2) Conference proceedings abstracts, international meetings. 112. Moja EA, Benedetti F, Gessa GL (1993) Effect of tryptophan-free diets on brain neurotransmitters and behavior in rats and humans. International Symposium on Perinatal Nutrition and Brain Development. Troina, 21-24 novembre 1993. Book of abstracts, pp.40-41. th 113. Moja EA, Benedetti F (1995) Sexual behavior in male and female rats after tryptophan-free diet. 8 International Meeting on Tryptophan Research. Padova, 25-29 giugno 1995. Book of abstracts, L11. 114. Sforzini L, Benedetti F, Colombo C, Maffei C, Smeraldi E. (1996) Clozapine in the treatment of Borderline Personality Disorder. 2nd European Congress on Personality Disorders - Diagnostic assessment and therapeutic strategies in personality disorders. Milano, 26-29 giugno 1996. Book of abstracts, p. 35. 22 Dr Francesco Benedetti Curriculum vitae 115. Colombo C, Benedetti F, Barbini B, Campori E, Smeraldi E. (1998) The treatment of a depressive episode in bipolar patients: sustaining the effect of sleep deprivation. Workshop on novel therapeutic strategies in the schizophrenia spectrum and mood disorders. International academy for biomedical and drug research, Venezia, 13-14 marzo 1998. Book of abstracts, pp. 89-92. 116. Campori E, Benedetti F, Barbini B, Colombo C, Smeraldi E. (1998) Effect of sleep deprivation combined with dopamine agonist amineptine in bipolar depression. 21st CINP Congress; 1998 Jul 12-16, Glasgow. Book of abstracts, p. 268. 117. Benedetti F, Colombo C, Campori E, Barbini B, Smeraldi E. (1998) Day-to-day mood changes during antidepressant treatment. 21st CINP Congress; 1998 Jul 12-16, Glasgow. Book of abstracts, p. 270. 118. Colombo C, Benedetti F, Sforzini L, Smeraldi E. (1998) Clozapine in the treatment of severe borderline personality disorder. 21st CINP Congress; 1998 Jul 12-16, Glasgow. Book of abstracts, p. 417. 119. Benedetti F (1998) Sleep deprivation: sustaining the clinical effect. International workshop - Sleep deprivation: methods, techniques, rationale and perspectives. Milano, December 11. 120. Colombo C, Benedetti F, Barbini B, Campori E, Smeraldi E. (1999) Sleep deprivation: an efficacious alternative treatment in bipolar depressives. World Federation of Societies of Biological Psychiatry - European regional congress. Firenze, 1999 April 8-11. Book of abstracts, p. 175-176. 121. Benedetti F, Bernasconi A, Lorenzi C, Pontiggia A Serretti A,, Colombo C, Smeraldi E (2003) Glycogen synthase-kinase 3β influences age at onset of bipolar disorder. XIth World Congress of Psychiatric Genetics. Quebec City, October 4-8. 122. Serretti A, Cusin C, Lorenzi C, Benedetti F, Pirovano A, Arnoldi A, Zanardi R, Colombo C, Smeraldi E (2003) Genetic predictors of antidepressant efficacy: the state of the art. XIth World Congress of Psychiatric Genetics. Quebec City, October 4-8. 123. Mandelli L, Serretti A, Benedetti F, Lorenzi C, Pirovano A, Colombo C, Smeraldi E (2003) Genetic dissection of psychopatological symptoms: insomnia in mood disorders and CLOCK gene polymorphism. XIth World Congress of Psychiatric Genetics. Quebec City, October 4-8. 124. Benedetti F, Pontiggia A, Bernasconi A, Colombo C, Lorenzi C, Serretti A, Smeraldi E (2005) GSK3-β and the molecular clock as novel targets for lithium salts and clinical chronotherapeutics. 1st International Congress of Applied Chronobiology and Chronomedicine. Antalya, June 1-5. Book of Abstracts, p. 51. 125. Benedetti F, Radaelli D, Bernasconi A, Blasi V, Cadioli M, Colombo C, Falini A, Scotti G, Smeraldi E. (2005) Changes in right DLPFC (BA9) neural responses parallel response to sleep deprivation in bipolar depression. 1st International Congress of Applied Chronobiology and Chronomedicine. Antalya, June 1-5. Book of Abstracts, p. 51. 126. Benedetti F, Bernasconi A, Radaelli D, Blasi V, Cadioli M, Colombo C, Falini A, Scotti G, Smeraldi E (2005) Neural correlates of antidepressant response to sleep deprivation : a 3.0T BOLD fMRI event-related study of moral thinking. 1st International Congress of Applied Chronobiology and Chronomedicine. Antalya, June 1-5. Book of Abstracts, p. 52. 127. Benedetti F (2005) Light treatment of bipolar disorder. 1st International Congress of Applied Chronobiology and Chronomedicine. Antalya, June 1-5. Book of Abstracts, p. 69. 128. Benedetti F, Mandelli L, Serretti A, Lorenzi C, Pirovano A, Colombo C, Smeraldi E (2005) Genetic dissection of psychopathological symptoms: insomnia in mood disorders and clock gene polymorphism. 1st International Congress of Applied Chronobiology and Chronomedicine. Antalya, June 1-5. Book of Abstracts, p. 76. 129. Benedetti F, Serretti A, Artioli P, Mandelli L, Lorenzi C, Smeraldi E (2005) How do genes exert their role? PER3 variants and possible influences on mood disorder phenotypes. 1st International Congress of Applied Chronobiology and Chronomedicine. Antalya, June 1-5. Book of Abstracts, p. 77. 130. Calabrese G, Benedetti F, Bernasconi A, Cadioli M, Colombo C, Redaelli D, Smeraldi E, Scotti G, Falini A. (2005) The Glutamatergic Hypothesis Of Sleep Deprivation Treatment In Depression: Proton MRS Study At 3 Tesla. International Society For Magnetic Resonance In Medicine - ISMRM Workshop On MR Spectroscopy For Neuropsychiatric Disorders. Banff, October 15-17. 131. Benedetti F. (2006) Bold fMRI of the antidepressant response. International Workshop on New Techniques for the Clinical Psychiatrist. Milano, May 11-12. Book of Abstracts, p. 13. 132. Benedetti F (2006) Short and long term chronotherapeutics of bipolar depression. International Workshop on New Techniques for the Clinical Psychiatrist. Milano, May 11-12. Book of Abstracts, p. 21. 133. Benedetti F (2010) Sommeil et Rythmes Circadiens dans les troubles bipolaires à début précoce. Conferences de Chenevier 2009-2010 - Age et mode de début des maladies psychiatriques: Perspectives cliniques, étiologiques et thérapeutiques. Paris, Creteil, Mardi 12 Janvier 2010. 134. Benedetti F (2010) Brain imaging of therapeutic response in mood and anxiety disorders. IV Brixia International Conference, Brescia June 17-19, 2010 23 Dr Francesco Benedetti Curriculum vitae 135. Benedetti F (2010) Successful chronotherapeutics normalizes brain imaging correlates of emotional processing in bipolar depression. SLTBR, Vienna, July 1-3. Society for Light Treatment and Biol Rhythm Abst 22:18. 136. Wirz-Justice A, Bader A, Frisch U, Stieglitz RD, Alder J, Bitzer J, Hösli I, Jazbec S, Benedetti F, Terman M, Wisner K, Riecher-Rössler A (2011) Light therapy for antepartum depression. A randomized, double-blind, placebo-controlled study. 4th World Congress on Women's Mental Health. Madrid, Spain March 16-19. Conference proceedings abstracts, italian meetings. 137. Antonietti A, Benedetti F, Fontana P, Moja EA (1988) Effetti di prolungate deprivazioni di alcool sul consumo etilico spontaneo del ratto. Atti del VII Congresso Nazionale della Divisione Ricerca di Base in Psicologia, pp. 79, Palermo. 138. Moja EA, Benedetti F, Poggioli R (1989) Comportamento sessuale in ratte dopo somministrazione di diete di aminoacidi prive di triptofano. Atti dell' VIII Congresso Nazionale della Divisione Ricerca di Base in Psicologia, pp. 37-39, Trieste. 139. Benedetti F, Becci R, Moja EA (1990) Comportamenti sessuali in ratti maschi e femmine: possibile differente ruolo della serotonina. Atti del IX Congresso Nazionale della Divisione Ricerca di Base in Psicologia, pp. 273275, Bologna. 140. Benedetti F, Sforzini L, Colombo C, Smeraldi E (1997) Terapia acuta e a medio termine con clozapina a basso dosaggio nel disturbo di personalità borderline. II Congresso Nazionale della Società Italiana di Psicopatologia. Pisa, 20-23 febbraio 1997. 141. Benedetti F (1998) Fluttuazioni circadiane della sintomatologia depressiva durante il trattamento antidepressivo. VIII congresso della Società Italiana di Psichiatria Biologica, Napoli. 142. Colombo C, Benedetti F, Campori E, Barbini B, Smeraldi E (1999) Deprivazione di sonno: tool diagnostico e strategia di potenziamento nel disturbo bipolare. IV Congresso nazionale della Società Italiana di Psicopatologia; Firenze. 143. Benedetti F, Colombo C, Barbini B, Campori E, Cigala M, Smeraldi E (2000) La deprivazione di sonno nel trattamento della depressione bipolare. V Congresso nazionale della Società Italiana di Psicopatologia; Roma, 23-27 febbraio 2000. Giornale Italiano di Psicopatologia 6(Suppl 1):80. 144. Benedetti F (2000) Tecniche di potenziamento nella terapia antidepressiva. Workshop: Disturbi dell’umore e ossessività. Parigi 5-6 maggio 2000. Libro degli abstract, pp. 3-4. 145. Benedetti F, Smeraldi E (2000) Genetica della risposta antidepressiva. Il Disturbo Bipolare: clinica e terapia.. Parma, 3 giugno 2000. Libro degli abstract, pag.5-6. 146. Benedetti F, Colombo C, Barbini B, Campori E, Cigala Fulgosi M, Smeraldi E (2000) La deprivazione di sonno nella terapia della depressione bipolare. XLII Congresso Nazionale della Società Italiana di Psichiatria, Torino 16-21 ottobre. Libro degli abstract, pag. 370. 147. Benedetti F, Colombo C, Barbini B, Campori E, Cigala Fulgosi M, Smeraldi E (2000) La deprivazione di sonno nella terapia della depressione bipolare. In: Dal pregiudizio alla cittadinanza. Atti del XLII Congresso Nazionale della Società Italiana di Psichiatria, pag.721-724. 148. Benedetti F, Barbini B, Campori E, Cigala Fulgosi M, Colombo C, Smeraldi E (2001) Strategie di potenziamento non farmacologico. VI Congresso internazionale della Società Italiana di Psicopatologia. Roma, 21-25 febbraio 2001. Giornale Italiano di Psicopatologia 7(Suppl 1):12-13. 149. Benedetti F, Barbini B, Campori E, Cigala Fulgosi M, Colombo C, Smeraldi E (2001) Sole, luce e terapia dei disturbi dell’umore. VI Congresso internazionale della Società Italiana di Psicopatologia. Roma, 21-25 febbraio 2001. Giornale Italiano di Psicopatologia 7(Suppl 1):81-82. 150. Benedetti F, Barbini B, Campori E, Cigala Fulgosi M, Colombo C, Smeraldi E (2001) Deprivazione di sonno e disturbo bipolare. VI Congresso internazionale della Società Italiana di Psicopatologia. Roma, 21-25 febbraio 2001. Giornale Italiano di Psicopatologia 7(Suppl 1):71-72. 151. Zanardi R, Serretti A, Rossini D, Benedetti F, Cusin C, Smeraldi E (2001) Influenza del pindololo sul sistema serotoninergico: aspetti clinici e genetici. VI Congresso internazionale della Società Italiana di Psicopatologia. Roma, 21-25 febbraio 2001. Giornale Italiano di Psicopatologia 7(Suppl 1):12. 152. Cipri D, Gnech M, Griner A, Lotumulo A, Vaccarella D, Marras A, Bissaro D, Franchini L, Benedetti F (2001) Assistenza infermieristica al paziente bipolare depresso in corso di terapia con deprivazione di sonno ed esposizione a luce brillante. XXIII Congresso Nazionale dell’Associazione Nazionale Infermieri Neuroscienze. Rimini, 4-5 ottobre 2001. 24 Dr Francesco Benedetti Curriculum vitae 153. Benedetti F, Colombo C, Barbini B, Campori E, Pontiggia A, Smeraldi E (2001) I ritmi del sonno e della veglia, della luce e del buio nella terapia dei disturbi dell’umore. XI Congresso nazionale dell'Associazione Italiana di Medicina del Sonno. Pisa, 14-17 ottobre 2001 154. Lucca A, Benedetti F, Moja EA, Smeraldi E. (2002) Deplezioni selettive con aminoacidi: una rassegna degli effetti biochimici e comportamentali. VII Congresso internazionale della Società Italiana di Psicopatologia. Roma, 19-23 febbraio 2002. Giornale Italiano di Psicopatologia . 155. Benedetti F, Colombo C (2003) Ritmi biologici e disturbo bipolare. Convegno su Ritmi Biologici e Disturbi Mentali, Roma, 11 giugno 2003. Psichiatria e Psicoterapia, 22 (2 Suppl.): 29-33. 156. Serretti A, Zanardi R, Benedetti F, Cusin C, Pirovano A, Artioli P, Colombo C (2003) Applicazione della farmacogenetica ai disturbi dell’umore. XLIII Congresso Nazionale della Società Italiana di Psichiatria, Bologna 19-24 ottobre 2003. 157. Smeraldi E, Benedetti F. (2004) Controllo genetico dei ritmi biologici e risposta antidepressiva. XIII Congresso della Società Italiana di Neuropsicofarmacologia. Bologna, 1-4 giugno 2004. 158. Benedetti F, Colombo C, Barbini B, Pontiggia A, Cigala Fulgosi M, Bernasconi A (2005) Cronoterapia clinica dei disturbi dell’umore. X Congresso Nazionale della Società Italiana di Psicopatologia. Roma, 22-26 febbraio 2005. Giornale Italiano di Psicopatologia 11(Suppl 1): 80-81. 159. Benedetti F., Smeraldi E. (2006) La depressione come problema cronobiologico. XV Congresso della Società Italiana di Neuropsicofarmacologia. Genova, 6-9 giugno 2004. Libro degli abstract, pag. 355-6. 160. Dallaspezia S., Benedetti F., Bernasconi A., Blasi V., Cadioli M., Colombo C., Falini A., Radaelli D., Scotti G., Smeraldi E. (2006) Correlazione tra attività basale cerebrale e risposta antidepressiva ai trattamenti cronoterapeutici: uno studio di risonanza magnetica funzionale. XV Congresso della Società Italiana di Neuropsicofarmacologia. Genova, 6-9 giugno 2004. Libro degli abstract, pag. 527-9. 161. Bernasconi A., Calabrese G., Benedetti F., Radaelli D., Dallaspezia S., Cadioli M., Colombo C., Falini A., Scotti G., Smeraldi E. (2006) Correlazione tra risposta al trattamento antidepressivo con deprivazione totale di sonno e i cambiamenti nei livelli cerebrali di glutammato: uno studio di risonanza magnetica ad alto campo. XV Congresso della Società Italiana di Neuropsicofarmacologia. Genova, 6-9 giugno 2004. Libro degli abstract, pag. 530-2. 162. Cigala Fulgosi M., Benedetti F., Barbini B., Pontiggia A., Colombo C., Dallaspezia S., Smeraldi E. (2006) Cronoterapia nella depressione bipolare resistente: follow up a 9 mesi. XV Congresso della Società Italiana di Neuropsicofarmacologia. Genova, 6-9 giugno 2004. Libro degli abstract, pag. 533-5. 163. Radaelli D., Bernasconi A., Benedetti F., Blasi V., Cadioli M., Colombo C., Falini A., Scotti G., Smeraldi E. (2006) Influenza del polimorfismo nel trasportatore della serotonina sulle attivazioni cerebrali in pazienti depressi. XV Congresso della Società Italiana di Neuropsicofarmacologia. Genova, 6-9 giugno 2004. Libro degli abstract, pag. 536-8. 164. Pontiggia A., Benedetti F., Bernasconi A., Colombo C., Lorenzi C., Serretti A., Smeraldi E. (2006) La GSK3-ß come possibile target d’azione nel trattamento del Disturbo Bipolare. XV Congresso della Società Italiana di Neuropsicofarmacologia. Genova, 6-9 giugno 2004. Libro degli abstract, pag. 539-41. 165. Benedetti F (2008) Determinanti genetiche della produzione di neurotrofine e loro influenza sulla neuroanatomia funzionale del paziente depresso. XII Congresso Nazionale della Società Italiana di Psicopatologia. Roma, 19-23 febbraio 2008. Giornale Italiano di Psicopatologia 14(Suppl 1):120. 166. Benedetti F (2008) Stress, risposta infiammatoria, orologio biologico e cronoterapia della depressione XVI Congresso della Società Italiana di Neuropsicofarmacologia - Dalla neurobiologia all'appropriatezza della terapia. Milano, 24-26 giugno 2008. CD degli abstract, S6-4. 167. Benedetti F (2008) Cronoterapia clinica della depressione. XVIII CongressoNazionale della Società Italiana diMedicina del Sonno (AIMS). Bari, 9-12 Novembre. Libro degli abstract, pag.119. 168. Poletti S, Benedetti F, Riccaboni R, Radaelli D, Cavallaro R, Falini A, Scotti G., Smeraldi E (2008) The neural correlates of theory of mind and empathy in schizophrenia. Workshop del Gruppo di Studio di Neuroradiologia Funzionale dell'Associazione Italiana di NeuroRadiologia: Advanced MR Brain Imaging. Milano, 20-21 novembre. Materiale didattico, pag.24. 169. Absinta M, Redaelli D, Pagani E, Benedetti F, Filippi M (2008) Disconnessione strutturale del network emotivo in pazienti con disturbo bipolare. Workshop del Gruppo di Studio di Neuroradiologia Funzionale dell'Associazione Italiana di NeuroRadiologia: Advanced MR Brain Imaging. Milano, 20-21 novembre. Materiale didattico, pag.25. 170. Bernasconi A, Calabrese G, Benedetti F, Radaelli D, Dallaspezia S, Cadioli M, Colombo C, Falini A, Scotti G, Smeraldi E (2008) Spectroscopic changes after chronotherapy of bipolar depression. Workshop del Gruppo di Studio di Neuroradiologia Funzionale dell'Associazione Italiana di NeuroRadiologia: Advanced MR Brain Imaging. Milano, 20-21 novembre. Materiale didattico, pag.87. 25 Dr Francesco Benedetti Curriculum vitae 171. Benedetti F, Radaelli D, Poletti S, Bernasconi A, Dallaspezia S, Colombo C, Falini A, Scotti G, Smeraldi E (2008) Stressful life events bias neural correlates of tasks targeting the depressive biases in information processing in patients affected by mood disorders. Workshop del Gruppo di Studio di Neuroradiologia Funzionale dell'Associazione Italiana di NeuroRadiologia: Advanced MR Brain Imaging. Milano, 20-21 novembre. Materiale didattico, pag.89. 172. Radaelli D, Benedetti F, Bernasconi A, Dallaspezia S, Falini A, Colombo C, Scotti G, Smeraldi E (2008) Personality disorders and depression: a fMRI study. Workshop del Gruppo di Studio di Neuroradiologia Funzionale dell'Associazione Italiana di NeuroRadiologia: Advanced MR Brain Imaging. Milano, 20-21 novembre. Materiale didattico, pag. 91. 173. Benedetti F (2009) La dimensione stagionale nei disturbi dell’umore (simposio). XIII Congresso Nazionale della Società Italiana di Psicopatologia. Roma, 10-14 febbraio 2009. 174. Benedetti F (2009) Traslazione della ricerca clinica nel disturbo bipolare. XIII Congresso Nazionale della Società Italiana di Psicopatologia. Roma, 10-14 febbraio 2009. 175. Benedetti F (2010) Le tecniche di cronoterapia della depressione nella pratica clinica ospedaliera e ambulatoriale: indicazioni all’uso, trattamenti, risultati attesi. XIV Congresso Nazionale della Società Italiana di Psicopatologia. Roma, 16-20 febbraio 2010. 176. Benedetti F (2010) Neuroimaging nella psicofarmacologia dei disturbi dell’umore. XVII Congresso Nazionale della Società Italiana di NeuroPsicoFarmacologia. Cagliari, 22/25 settembre 2010 177. Benedetti F (2011) L’effetto delle esperienze avverse nell’infanzia sulla struttura e la funzione del cervello adulto. Percorsi internazionali di studio in psichiatria, IV incontro, Roma 23-26 novembre. Workshops, seminars, lectures, invited speaker 178. Benedetti F (1997) Deprivazione di sonno e disturbo bipolare. Creatività e distruttività nei disturbi dell’umore. Napoli, 7-8 aprile. 179. Benedetti F (1998) Efficacia antidepressiva della deprivazione di sonno. The clinical usefulness of sleep deprivation in the treatment of depression. Milano, 11 dicembre. 180. Benedetti F (1999) SSRI potentiation as a clinical and research tool in bipolar disorder. Mount Sinai School of Medicine and San Raffaele Scientific Institute scientific exchange program. New York, november 181. Benedetti F (2000) Mount Sinai School of Medicine and San Raffaele Scientific Institute scientific exchange program. Boston, USA, novembre. 182. Benedetti F (2001) Trattamento farmacologico del disturbo di personalità borderline. 2° Congresso Nazionale di Psichiatria - Bordeline: continuità discontinuità. Ascoli Piceno, 14-16 giugno. 183. Benedetti F (2003) Immediate changes in depressive information processing after biological rhythm manipulations. International workshop on emotions in psychiatric disorders. Milano, 3-4 marzo. 184. Benedetti F (2003) Basi biologiche dell’intervento non farmacologico nella depressione. Il nuovo possibile nella riabilitazione psichiatrica. Milano 17 settembre 2003. 185. Benedetti F (2004) L’orologio biologico come bersaglio della terapia antidepressiva. Terapia somatica della depressione. Milano, 9 giugno 2004. 186. Benedetti F (2004) Etica del suicidio. Malattia del panico. 2-4 Luglio - ONLUS - Scuola di perfezionamento e formazione in neuroscienze - Centro Congressi S. Paolo della Croce – Impruneta 187. Benedetti F (2004) Psichiatria del suicidio. Malattia del panico. 2-4 Luglio - ONLUS - Scuola di perfezionamento e formazione in neuroscienze - Centro Congressi S. Paolo della Croce – Impruneta 188. Benedetti F (2005) Neural correlates and genetic determinants of antidepressant response. Chronobiology of depression: classic theories and new vistas. Napoli, July 12. 189. Benedetti F (2005) Brain imaging of mood disorders. New Trends in Psychobiology. Milano, June 10. 190. Benedetti F (2005) Serate informative “Soffriva di depressione ...ed ora sta bene”. Lissone, 7 e 14 novembre 191. Benedetti F (2006) BOLD fMRI of the antidepressant response. International Workshop on New techniques for the clinical psychiatrist. Milano, 11-12 maggio. 192. Benedetti F (2006) Short- and long-term chronotherapeutics of bipolar depression. International Workshop on New techniques for the clinical psychiatrist. Milano, 11-12 maggio. 193. Benedetti F (2006) Modificazioni periodiche del cervello e la cronobiologia dei distrubi dell’umore. Il cervello che cambia nei disturbi mentali. Roma, 10-11 novembre. 194. Benedetti F (2006) Chronotherapeutics in a psychiatric ward. Chronobiology in psychiatry – International Simposium. Basel, September 11. 195. Benedetti F (2006) I ritmi del cervello. Porte aperte alle Neuroscienze. Milano, 18 novembre. 26 Dr Francesco Benedetti Curriculum vitae 196. Benedetti F (2007) An updated anatomy of melancholy: Uncertain neural boundaries between thinking and feeling. Are persons more than social objects? the emergence of persons: nature and society. Cesano Maderno, 28-29 maggio. 197. Benedetti F (2007) Images and emotions in mood disorders. Workshop on cognitive psychopharmacology. Milano, 14 giugno. 198. Benedetti F (2007) Neural and genetic correlates of adverse childhood events, current depression, and antidepressant response. Workshop on neural basis and ontogeny of depressive psychopathology. Milano, 25 ottobre. 199. Benedetti F (2007) Modello anatomo-funzionale dell’ansia. La paura e le metamorfosi dell’ansia: un breve viaggio dalla fenomenologia alla terapia. Piacenza, 19 ottobre. 200. Benedetti F (2007) Emozione e percezione. Seminari della Facoltà di Filosofia, Cesano Maderno, 14 novembre 201. Benedetti F (2008) L'orologio biologico nel disturbo bipolare: dalla genetica al neuroimaging. Biologia e Fisiopatologia delle demenze e delle malattie mentali. Brescia, IRCCS Centro San Giovanni di Dio – Fatebenefratelli, 17 Marzo. 202. Benedetti F (2008) Chronobiology and chronotherapeutics in clinical psychiatry. PhD program in Pharmacology and Toxycology, University of Milan. Milano, 11 aprile. 203. Benedetti F (2008) Brain Imaging dei disturbi dell’umore. Giornata di studio sul disturbo bipolare: dalle scienze di base alla clinica. Senigallia, 19 aprile. 204. Benedetti F (2008) Ritmi biologici ed influenze fisiche ambientali nel decorso naturale del Disturbo Bipolare. Seminari Psichiatrici Europei di Ventotene – I edizione: Il Disturbo Bipolare. Ventotene, 15-17 maggio. 205. Benedetti F (2008) Interaction of adverse childhood experiences and schizophrenia on neural correlates of social cognition. Cognition in Schizophrenia: A Satellite Meeting of the Schizophrenia International Research Society. Venezia, 21 giugno. 206. Benedetti F (2008) Ritmi del cervello. Il cervello: dai neuroni alla coscienza alle emozioni. Milano, 18 ottobre. Nell’ambito di Bergamo Scienza, VI edizione, 3-19 ottobre 207. Colombo C, Ronchi P, Politi E, Benedetti F (2008) L’attualità di ansia e depressione. Il cervello: nuove sfide contro le sue malattie. Milano, 18 ottobre. Nell’ambito di Bergamo Scienza, VI edizione, 3-19 ottobre 208. Benedetti F (2008) Chronotherapeutics of mood: light therapy and sleep deprivation for bipolar depression. Pediatric and adult psychosis: focus on schizophrenia and bipolar disorder. Verona, 27 ottobre. 209. Benedetti F, Radaelli D, Poletti S (2008) Correlati neurali nella clinica e terapia dei disturbi dell’umore e della schizofrenia. Aggiornamenti in neurobiologia e terapia psichiatrica. Mestre, 14 novembre. 210. Benedetti F (2008) Imaging strutturale, metabolico e funzionale nei disturbi dell'umore. Workshop del Gruppo di Studio di Neuroradiologia Funzionale dell'Associazione Italiana di NeuroRadiologia: Advanced MR Brain Imaging. Milano, 20-21 novembre. 211. Benedetti F (2009) The rhythms of life. Influence of light on mood and chronobiological rhythms in everyday life. Light and Well-Being, Milano, 25 febbraio. 212. Benedetti F (2009) Imaging strutturale, metabolico e funzionale nei disturbi dell’umore: dallo stress infantile alla patologia attuale. Depressione e disturbo bipolare: dalla ricerca alla pratica clinica. Senigallia, 27 marzo 213. Benedetti F (2009) Brain Imaging funzionale nei disturbi dell’umore. Mente, cervello, comportamento: l’uso della Risonanza Magnetica Funzionale in psichiatria. Terni, 7-8 maggio. 214. Benedetti F (2009) Le alterazioni dei ritmi biologici seguono o inducono la depressione? Seminari Psichiatrici Europei di Ventotene, II ed.: Le Depressioni, 21-23 maggio. 215. Benedetti F (2010) Cronoterapia dei Disturbi dell’Umore. Università Cattolica del Sacro Cuore, Roma, 12 Aprile. 216. Benedetti F (2010) Cronobiologia. Il futuro della depressione: lo sviluppo delle conoscenze, l’evoluzione delle terapie. Sermoneta, 16 -18 settembre. 217. Benedetti F (2010) La patologia della sostanza bianca nel disturbo bipolare. III Giornata di studio sul disturbo bipolare, Pesaro 1 Ottobre 2010. 218. Benedetti F (2010) Genetica dei ritmi circadiani e psicopatologia dell’umore. Argomenti di neuropsichiatria: alcune aree di confine, Milano 7-8 Ottobre. 219. Benedetti F (2011) The influence of adverse childhood experiences on structure and function of the adult human brain. hSR Scientific Retreat 2011, Stresa 10-12 febbraio. 220. Benedetti F (2011) Immunità e disturbo bipolare. 11° corso residenziale di neuroimmunologia, Bergamo 16-19 marzo. 221. Benedetti F (2011) I ritmi biologici. Seminari Psichiatrici Europei di Ventotene, IV ed.: Cervello e clinici tra ansia e depressione, Ventotene, 26-28 maggio. 222. Benedetti F (2011) Insomnia and chronobiology. 1st Alpine Sleep Summer School, Lugano 22-27 agosto. 27 Dr Francesco Benedetti Curriculum vitae 223. Benedetti F (2011) Quale ruolo dei ritmi biologici nella patogenesi e nella terapia? Psichiatria Futura - Che cosa c’è nel futuro del disturbo bipolare? Sermoneta, 30 settembre. 224. Benedetti F (2011) L’infiammazione nella patogenesi e nella terapia del disturbo bipolare. IV Giornata di studio sul disturbo bipolare, Pesaro 1 Ottobre. Media coverage - Bhattacharjee Y (2007) Psychiatric research. Is internal timing key to mental health? Science 317:1488-90 Lamberg L (2009) Targeting biologic clock may improve treatment of psychiatric disorders. Psychiatric News 44(8):28 Studwell J (2004) All sleepless and light. Financial Times Magazine, Oct 23:20-24. Porciani F (2007) Notti in bianco e si torna sereni. Corriere della Sera, 14 Ott:61. Capelli F (2007) Accendi la luce. Vanity Fair, 27 Sett:350-4. Zambelli L (2000) Light therapy, una lampada per far tornare il buonumore. La Repubblica/Kataweb Salute 24 Nov 28