Center for Integrative Mediterranean Studies Bonino Pulejo Foundation Organizing Secretariat Francesco Cimino, Mariateresa Cristani Dipartimento Farmaco-Biologico, Università di Messina Tel +39 090 6766574 Fax. +39 090 6766474 e-mail: [email protected] Scientific Committee Giuseppe P. Anastasi (University of Messina) Reyes González Roncero (University of Córdoba) Rakesh C Kukreja (Virginia Commonwealth University) Heber H. Newsome (Virginia Commonwealth University) Antonella Saija (University of Messina) Manuel Torres Aguilar (University of Córdoba) INTERNATIONAL CONFERENCE ON FREE RADICALS & OXIDATIVE STRESS IN BIOLOGY AND MEDICINE September 2626-27, 2008 Sponsored by: Federfarma Ordine dei Farmacisti della Provincia di Messina University of Messina, Polo Didattico dell’Annunziata School of Pharmacy, Aula Magna Ordine Provinciale Farmacisti Vibo Valentia University of Córdoba Spain University of Messina Italy Virginia Commonwealth University USA FRIDAY, SEPTEMBER 26 9:30 SATURDAY, SEPTEMBER 27 Welcome addresses and meeting introduction Welcome back Pharmacy students, academic year 2008/09, Bisignano G., UniME, Dean of the School of Pharmacy 10:00 Opening lecture – INTRODUCED BY ROMANO A. (UNIME) Gembillo G. (UniMe) – Oxygen: simple or complex element? 10:30 Session 1 CHAIRMAN: COGLITORE S. (UNIME) Cucinotta D., Russo G.T., (UniMe) – Hyperhomocysteinemia in type 2 diabetes: vascular risk factor or biomarker? Kukreja R.C., Smolenski A, Lohmann SM, Das A (VCU) – Protein Kinase G protects cardiomyocytes against ischemia/reoxygenation injury: Essential role of reactive oxigen species and mitochondrial KATP channels. Manasseri L. (UniME) - Mediterranean Diet, natural antioxidants and cardioprotection. Coffee-break 11:45 Session 2 - CHAIRMAN: VERMIGLIO M. (UNIME) Magaudda L., Pagano F. (UniME) - Oxidative stress and sports. Nicita Mauro V., Basile G. (UniME) - Smoking, oxidative stress and aging. Valacchi G. (UniSI) - Cigarette smoke affects vitamin E uptake. 9:30 Session 1 – CHAIRMAN: ANASTASI G.P. (UNIME) Vita G., Rodolico C., Messina S. (UniME) - Oxidative stress in muscular dystrophies and animal models. Block M.L. (VCU) - Microglia-derived reactive oxygen species and progressive dopaminergic neuron damage. Ientile R. (UniME) – Hyperhomocysteinemia and oxidative stress, risk factors in neurodegenerative diseases. Morroni F., Hrelia P., Cantelli Forti G., Tarozzi A. (UniBO) – Isothiocyanates and Parkinson disease: novel targets for neuroprotection. Coffee-break 11:30 Session 2 - CHAIRMAN: RUBERTO G.(CNR, Valverde, CT R) Serafini M. (INRAN, Rome) – From antioxidant vitamin to chocolate: how can we modulate oxidative stress in vivo? Delgado-Lista J., Pérez-Martínez P., López-Miranda J., Pérez-Jiménez F. (UCO) - Postprandial intake of olive oil and oxidative stress. Giovinazzo C. (UniME) – Antioxidants supplements: new frontiers. Virgili F., Canali R. (INRAN, Rome) - Combining in vivo and in vitro models to investigate the dietary modulation of inflammatory response. Lunch Lunch 14:30 Session 3 - CHAIRMAN: AVERSA M.C. (UNIME) González-Aragón D., Jódar L., Alcaín F.J., Ariza J., Lopez-Domínguez J.A., Burón I., Barbarroja N., López-Pedrera Ch., de Cabo R., Villalba J.M. (UCO) - Role of NAD (P)H: quinone oxidoreductase 1 activity in the control of cell growth. McDonagh B., Padilla C.A., Bárcena J.A. (UCO) – Dynamics of the redox proteome and the mechanisms of antioxidant defense. Spagna G., Todaro A. (UniCT) – Characterization and role of polyphenol oxidase and peroxidase in browning of vegetable foods. Crupi V., Majolino D., Venuti V., Mondello M.R., Pergolizzi S. (UniME) - Spectroscopic study of morphological changes in biological tissues: some study cases. Vermiglio G., Acri G., Tripepi M.G., Faraone V., Testagrossa B. (UniME) – Oxidative stress physical implications: the new frontier. Coffee-break Delivery of the “Francesca Lo Verso” prize, Ordine Provinciale Farmacisti Vibo Valentia 17:00 Session 4 - CHAIRMAN: VIRGILI F. (INRAN, ROME) Metro D. (UniME) - Oxidative stress and neoplastic diseases. Traka M., Gasper A.V., Melchini A., Mithen R. (IFR, Norwick, UK) – Broccoli in prostate cancer: mechanisms derived from humans. Yager D.R., Braun K., Oh K. (VCU) - Expression and influence of heme oxygenase-1 in a model of burn injury. Mangino M.J., Lindell S., Southard J. (VCU) – The role of oxidative stress in organ preservation for transplantation. 14:30 Session 3 – CHAIRMAN: DE PASQUALE R. (UNIME) Macrì A., Santangelo C., Giovannini C., Masella R. (ISS, Rome) - Polyphenol properties and their biological activity. Cimino F. (UniME) - Biological activities of anthocyanins: an update. Ruberto G. (CNR, Valverde, CT) - Essential oils as antioxidants - Screening of biomolecular diversity. Minutoli R., Guglielmo L. (UniME) - Use of ecotoxicological biomarkers in zooplankton for the management and conservation of marine coastal and transitional waters ecosystem health. Coffee-break 16:30 Session 4 - CHAIRMAN: BISIGNANO G. (UNIME) Gómez Baena G., López Lozano A., Rangel O.A., Donaldson R.P., García-Fernández J.M., Díez J. (UCO) - Oxidative stress in Prochlorococcus: degradation of glutamine synthetase and effect on proteases gene expression. Fanelli R., Ricelli A. , Zjalic S. , Fabbri A. , Riverberi M. , Tomaino, Monteleone D. (UniRoma1; ICBCNR, Rome; UniME; Ministery of Health, Rome) - Control of oxidative stress and aflatoxin biosynthesis in Aspergillus parasiticus by Lentinula edodes and Trametes versicolor glucans. Maugeri T. (UniME) – The VBNC state in microbes:a response induced by environmental stress. Conclusions –Newsome H.H. (VCU)