WORKSHOP MODERN VACCINES AND DELIVERY TECHNOLOGIES
October 14-15, 2010
Roma, Research Center Casaccia,
Conference Room, Building F-83
FINAL PROGRAMME
Thursday 14 October – 13.55 - 19.00
13.55 – 14.00
Welcome Address
Carmela MARINO – ENEA, Roma
In Silico Vaccinology
Chairman: Eugenio BENVENUTO
14.00 – 14.30
Invited Lecture
Filippo CASTIGLIONE – CNR-IAC, Roma
A computational model of cancer immunoprevention
14.30 – 14.50
Antonella PRISCO – CNR-IGB, Napoli
The lag time before a secondary response to antigen can be evoked can
vary: insights from a mathematical interpretation of experimental data
14.50 – 15.10
Caterina ARCANGELI – ENEA, Roma
Molecular modelling and simulation of virus-like particle as vaccine carrier
for heterologous antigens
Viral and Bacterial Vectors
Chairman: Andrea CARA
15.10 – 15.40
Invited Lecture
Lorena ZENTILIN – ICGEB, Trieste
Genetic vaccine platforms based on adeno-associated viral vectors
15.40 - 16.10
Invited Lecture
Antonella FOLGORI – Okairòs, Roma
Adenoviral vector delivery of vaccines: what has translated successfully
into humans
16.10 - 16.30
Giuseppe BORZACCHIELLO – Università di Napoli
E5 therapeutic vaccine against BPV-associated tumors and diseases
16.30 – 17.00 BREAK
17.00 – 17.30
Invited Lecture
Andrea CARA – ISS, Roma
Development and use of integrase-defective lentiviral vectors
17.30 – 17.50
Laura VANNUCCI – Università di Pisa
In vivo delivery of Herpes simplex type-1 glycoprotein B by a lentiviral
vector affords protection against genital herpes
17.50 – 18.10
Felicia GRASSO – ISS, Roma
Innovative strategy to control HPV-associated lesions: delivery of E7
oncoprotein by integrase defective lentiviral vectors
18.10 – 18.40
Invited Lecture
Gianni POZZI – Università di Siena
Gram-positive bacteria as vaccine delivery systems
18.40 – 19.00
Michele PESCIAROLI – ISS, Roma
Attenuated Salmonella enterica serovar Typhimurium lacking
ZnuABC transporter confers homologous protection in a murine
model of Salmonella enteritis
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Friday 15 October 9.00 – 12.40
Dendritic cells and adjuvants
Chairman: Piergiuseppe DE BERARDINIS
9.00 – 9.30
Invited Lecture
Maria FOTI –Università di Milano-Bicocca
Harnessing dendritic cell signatures for vaccine adjuvant development
9.30 – 10.00
Invited Lecture
Filippo BELARDELLI – ISS, Roma
Development of novel dendritic
immunotherapy
cell-based
strategies
of
cancer
10.00 – 10.20
Rossella SARTORIUS –CNR-IBP, Napoli
Filamentous bacteriophages targeting DEC-205 induce DC-maturation and
strong T cell responses in absence of adjuvants
10.20 – 10.50
Invited Lecture
Ennio DE GREGORIO – Novartis Vaccines & Diagnostics, Siena
Mechanism of action of vaccine adjuvants and delivery systems
10.50 – 11.10 BREAK
11.10 – 11.40
Invited Lecture
Selene BASCHIERI – ENEA, Roma
Intrinsic adjuvanticity of plant-derived vaccine carriers
11.40 – 12.00
Gabriella DI FELICE –ISS, Roma
Probiotic treatment induces intestinal regulatory dendritic and T cells,
and counter-regulates established TH2 responses and anaphylaxis in
a mouse model of food allergy
12.00 - 12.20
Antonio ROSATO – Università di Padova
Hyaluronic acid as a new prototypic “natural” adjuvant for vaccine
development
12.20 – 12.40
Annacarmen PETRIZZO – Istituto Nazionale Tumori, Napoli
Ex vivo analysis of idiotypic vaccine for HCV-related
lymphoproliferative disorders
12.40 – 15.00 LUNCH
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Friday 15 October 15.00 - 19.00
Structured Particles and Disease Models
Chairman: Eugenio BENVENUTO
15.00 – 15.30
Invited Lecture
Nancy L. HAIGWOOD – Oregon University, Beaverton, USA
Beneficial effects of neutralizing antibodies in HIV infection:
therapeutic and vaccine studies
15.30 – 16.00
Invited Lecture
Luigi BUONAGURO – Fondazione G. Pascale, Napoli
Virus-like particles as particulate vaccine
16.00 – 16.20
Paola DI BONITO – ISS, Roma
Aminolyzed poly(L-lactide) lamellar single crystals as an antigen
delivery system for vaccines against HPV16-associated lesions
16.20 – 16.40
Nunzia SCOTTI – CNR-IGV, Portici, Napoli
Expression of viral antigens (HIV-1/GAG,
VACV/A27L) in transgenic tobacco plastids
HPV-16/L1
and
16.40 – 17.00
Maria TROVATO – CNR-IBP, Napoli
E2 display as a novel vaccine approach to induce HIV-1 neutralizing
antibodies
17.00 – 17.20
Elena ILLIANO – ENEA, Roma
Recombinant viral proteins production in plants and bacteria for
vaccination and diagnostic purposes
17.20 – 17.40 BREAK
17.40 – 18.10
Invited Lecture
Mauro PISTELLO – Università di Pisa
Novel vaccine strategies against the feline immunodeficiency virus
18.10 – 18.30
Aldo VENUTI – Istituto Regina Elena, Roma
New perspective for HPV vaccine-based therapy of oropharyngeal
cancer
18.30 – 19.00 Concluding Remarks and Key Issues
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