Patronage requested
Faculty
A. ANICHINI (MILAN)
M.P. COLOMBO (MILAN)
V. BRONTE (VERONA)
M. DEL VECCHIO (MILAN)
M. DI NICOLA (MILAN)
M. FIGINI (MILAN)
J. GALON (PARIS)
G. KROEMER (PARIS)
M. MAIO (SIENA)
V. RUSSO (MILAN)
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C. TRIPODO (PALERMO)
Presentation
The 6th "Innovative therapy, monoclonal antibodies and beyond" Conference will convene a faculty
of leading international experts to discuss new therapeutic opportunities emerging from two
different areas of cancer pathology: aberrant cancer cell signaling and control of tumor growth by
the immune system.
The increasing knowledge of the molecular mechanisms responsible for neoplastic transformation,
the biology of cancer cells, and the immunological mechanisms regulating tumor-host interaction,
allowed us to identify and apply more effective anti-cancer biogical and immunological treatments.
To date, the immuno-biotherapy is a continuously evolving treatment modality and it is currently
integrated into the treatment algorythms of several different tumors. Furthermore, elucidating
resistance mechanisms and exploiting cancer vulnerabilities to therapeutics will ultimately improve
cancer therapy and patient care. In this context, metastatic melanoma represents a model in which
several mechanisms of intrinsic and adaptive resistance were identified and different approaches
have been testing in ongoing clinical trials.
This Conference explores topics that will appeal to clinicians, as well as, basic, translational, and
clinical scientists ranging from academics to industry. As in the past, the meeting will provide a
highly interactive forum in which leading experts will discuss clinical and pre-clinical data, providing
the audience with a broad overview of the most recent achievements in cancer biologic and
immunologic therapy.
Finally, several data support the combination of immunotherapies and standard treatments
representing an intriguing challenge, and at the same time a real opportunity
for the future therapeutic approaches.
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Friday, 22 January 2016
08.00-09.00
WELCOME COFFEE
Registration
09.00-09.10
Welcome remarks of Authorities
G. Apolone, Scientific Director of Fondazione IRCCS Istituto Nazionale dei Tumori (Milan)
G. Galmozzi, Medical Director of Fondazione IRCCS Istituto Nazionale dei Tumori (Milan)
09.10
Introduction • M. Di Nicola (Milan)
I SESSION: PRECLINICAL ASSAYES AND NOVEL BIOTARGETS
Chairmen: J. Galon (Paris), M.P. Colombo (Milan)
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09.20-09.50
Mechanisms of immune evasion to check-point inhibitors • V. Russo (Milan)
09.50-10.20
Control of melanoma dedifferentiation program and immune escape by NFATc2 • A. Anichini (Milan)
10.20-10.50
Myeloid stroma and regulation of adaptive immunity in cancer • V. Bronte (Verona)
10.50-11.20
Overriding the inflammatory microenvironment • C. Tripodo (Palermo)
11.20-11.50
Immunoscore: a prognostic and predictive tool • J. Galon (Paris)
11.50-12.00
General discussion
12.00-12.45
Keynote Lecture
Tumor cell metabolism • G. Kroemer (Paris)
Introduced by: M.P. Colombo (Milan)
12.45-14.00
BUFFET LUNCH
II SESSION: MONOCLONAL ANTIBODIES, CELL THERAPIES AND TK INHIBITORS
Chairmen: M. Del Vecchio (Milan), M. Di Nicola (Milan)
14.00-14.30
Hooking TRAIL-R2 to “educate” immune system to recognize
cancer cells • M. Figini (Milan)
14.30-15.00
TVEC vaccination: rationale and immunological background • M.P. Colombo (Milan)
15.00-15.30
Overcoming resistance to targeted therapy • M. Del Vecchio (Milan)
15.30-16.00
Immune checkpoint blockade for the treatment of advanced cancer • M. Maio (Siena)
16.00-16.30
Discussion
16.30-17.00
Conclusions • M. Del Vecchio (Milan)
CME Questionnaire compilation
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General Informations
CONGRESS VENUE
Aula A - Fondazione IRCCS
Istituto Nazionale dei Tumori
Via G. Venezian, 1 - MILAN
SCIENTIFIC COMMITTEE
Filippo de Braud
Massimo Di Nicola
Michele Del Vecchio
Medical Oncology Department
Fondazione IRCCS Istituto Nazionale dei Tumori
Milan
ORGANIZING SECRETARIAT
Nadirex International Srl
Via Riviera 39 · 27100 Pavia
Tel. +39.0382.525714/35
Fax +39.0382.525736
E-mail: [email protected]
www.nadirex.com
OFFICIAL LANGUAGE
English
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CME PROVIDER NR. 265
Nadirex International Srl
CME
The request for CME credits has been submitted to the Italian Ministry of Health.ID Nr. 265-143279 - CME credits: Nr. 7,5
The Congress is intended for the following figures:
- Physician (Ematology, Infectious Diseases, Oncology, Internal
Medicine, Transfusional Medicine)
- Biologist - Nurse - Biomedical laboratory technician
Participants: 100.
In order to obtain CME credits, participants must:
- Attend 100% of the sessions indicated in the programme
- Fill in the personal data form, the form evaluating the event, and the
learning questionnaire and give them to the Organizational Secretariat
at the end of the Congress.
The CME certificate will be sent by mail after the Congress to the address given on the personal data form.
REGISTRATION
The registration is free and includes:
• Partecipation in the conference work • Congress Kit
• Certificate of Attendance • CME credits Certificate
• Welcome coffee and lunch as scheduled
REGISTRATION INSTRUCTIONS
The Congress provides for a maximum of 100 participants.
To register fill in and submit the registration form within
January 20th, 2016 by fax to nr. +39.0382.525736 or online at
www.nadirex.com.
The Organizing Secretariat will confirm the registration by email.
Registration Form
Fill in using capital letters and send to:
NADIREX INTERNATIONAL s.r.l.
Via Riviera, 39-27100 Pavia
Fax +39.0382.525736 - [email protected] - www.nadirex.com
PLEASE COMPLETE THE FOLLOWING DETAILS
❑ PHISYCIAN
❑ BIOLOGIST
❑ NURSE
❑ BIOMEDICAL LABORATORY TECHNICIAN
Name ............................................................................ Surname .................................................................................................
Profession .................................................................... Discipline .................................................................................................
Specialized .....................................................................................................................................................................................
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Date .................................................................................... Signature ..........................................................................................
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SI RINGRAZIANO LE SEGUENTI AZIENDE
PER IL CONTRIBUTO NON CONDIZIONANTE: