Dangerous Liaisons translating cancer biology into better patients management 56th Annual Meeting of the Italian Cancer Society Ferrara, 11-13 September 2014 Università degli Studi di Ferrara 1 56 th Annual Meeting of the Italian Cancer Society Dangerous Liaisons translating cancer biology into better patients management CONGRESS VENUE Università degli Studi di Ferrara - Via Luigi Borsari, 46 - 44121 Ferrara OPENING CEREMONY VENUE Azienda Ospedaliero Universitaria di Ferrara Arcispedale Sant’Anna - Via Aldo Moro, 8 - 44124 Cona – Ferrara SIC SECRETARIAT Società Italiana di Cancerologia Via G. Venezian, 1 - 20133 Milan, Italy Phone +39 02 2666895 - Fax +39 02 2664342 E-mail: [email protected] www.cancerologia.it ORGANIZING SECRETARIAT C.S.C. S.r.l. Via L.S. Gualtieri, 11 - 06123 Perugia Tel+390755730617 - Fax +390755730619 www.csccongressi.it 2 Committee SIC SCIENTIFIC BOARD President Silvia Giordano (Institute for Cancer Research and Treatment, University of Turin, Candiolo, Italy) President Elect Gabriella Sozzi (IRCCS National Cancer Institute, Milan, Italy) Board Rita Falcioni (Regina Elena National Cancer Institute, Rome, Italy) Davide Melisi (University of Verona, Italy) Nicola Normanno (National Cancer Institute “G. Pascale”, Naples, Italy) Massimo Santoro (“Federico II” University, Naples, Italy) Elda Tagliabue (IRCCS National Cancer Institute, Milan, Italy) Giulia Taraboletti (“Mario Negri” Institute for Pharmacological Research, Bergamo, Italy) Giuseppe Viglietto (University of Magna Græcia, Catanzaro, Italy) Members under 35 Marco Macagno (University of Turin, Italy) Selena Ventura (Orthopaedic Rizzoli Institute, Bologna, Italy) Past President Riccardo Dolcetti (CRO-IRCCS, National Cancer Institute, Aviano, Pordenone, Italy) SCIENTIFIC AND ORGANIZING COMMITTEE Scientific Coordinator Massimo Negrini (University of Ferrara, Italy) Local Scientific Committee Giorgio Cavallesco, (University Hospital of Ferrara, Italy) Antonio Cuneo, (University Hospital of Ferrara, Italy) Francesco Di Virgilio, (University of Ferrara, Italy) Antonio Frassoldati, (University Hospital of Ferrara, Italy) Giovanni Lanza, (University Hospital of Ferrara, Italy) Alberto Liboni, (University Hospital of Ferrara, Italy) Paolo Pinton, (University of Ferrara, Italy) Silvia Sabbioni, (University of Ferrara, Italy) Mauro Tognon, (University of Ferrara, Italy) Stefano Volinia, (University of Ferrara, Italy) Silvano Capitani, (University of Ferrara, Italy) 3 Faculty Reuven Agami James Brenton George Adrian Calin Carlo M. Croce Ruggero De Maria Pier Paolo Di Fiore Janine Erler Brunangelo Falini Christopher Heeschen Simon Joosse Guido Kroemer Alberto Mantovani Clara Nervi Nicola Normanno Pier Paolo Pandolfi Pier Giuseppe Pelicci Vito Pistoia Valeria Poli Sabina Sangaletti Giampaolo Tortora 4 Cancer Institute - Amsterdam, The Netherlands Cancer Research UK Cambridge Institute - University of Cambridge, UK MD Anderson Cancer Center - University of Texas, Houston, Texas, USA Ohio State University - Ohio USA Regina Elena National Cancer Institute - Rome, Italy IFOM-IEO Campus - Milan, Italy BRIC-Biotech Research & Innovation Centre - University of Copenhagen, Denmark University of Perugia, Italy Spanish National Cancer Research (CNIO) - Madrid, Spain University Medical Center- Hamburg, Eppendorf , Germany INSERM, Institut Gustave Roussy, Villejuif, France University of Milan, Italy University La Sapienza - Rome, Italy National Cancer Institute “G. Pascale” - Naples, Italy Beth Israel Deaconess Medical Center - Boston, Massachussets, USA IFOM-IEO Campus - Milan, Italy Gaslini Children’s Hospital - Genoa, Italy University of Turin, Italy IRCCS National Cancer Institute - Milan, Italy University of Verona, Italy Programme at a glance Thursday September 11th - AULA MAGNA - OSPEDALE CONA 11.00 - 14.00 Pre-meeting SIC young investigators 14.00 - 14.30 Welcome Opening 14.30 - 15.15 Opening Lecture 15.15 - 18.30 Session 1: Cancer Microenvironment and inflammation 19.00 - 19.15 Bus Transfer 19.15 - 22.00 Welcome Cocktail Friday September 12th - POLO CHIMICO BIO MEDICO (Mammut) 08.00 Registration and poster hanging 08.30 - 10.30 Session 2: Non Coding RNAs and Epigenetics 10.30 - 11.00 Coffee Break 11.00 - 13.00 Poster Viewing With Authors 13.00 - 14.00 Light Lunch 14.00 - 15.30 Poster Discussion (4 parallel sessions) 15.30 - 18.00 Session 3: Cancer Stem Cells 18.15 - 19.15 SIC General Assembly 20.15 Social Dinner Saturday September 13th - POLO CHIMICO BIO MEDICO (Mammut) 08.30 - 09.15 Plenary Lecture 09.15 - 11.30 Session 4: “Translational” Therapy 11.30 - 12.30 Award Ceremony 12.30 - 13.30 Light Lunch 13.30 - 14.15 Giorgio Prodi Lecture 14.15 - 15.45 Session 5: Translational Diagnostics: NGS, Circulating Cells\Nucleic Acids 15.45 - 16.30 Closing Lecture 16.30 - 16.45 Closing Remarks 5 Thursday September 11th Scientific Programme Venue: AULA MAGNA - OSPEDALE CONA 6 11.00 - 14.00 Pre-meeting SIC young investigators 14.00 - 14.30 Welcome Opening 14.30 - 15.15 Opening Lecture Carlo M. Croce 15.15 - 18.30 Session 1: Cancer Microenvironment and Inflammation 15.15 - 15.45 15.45 - 16.00 16.00 - 16.30 16.30 - 16.45 16.45 - 17.15 17.15 - 17.45 Vito Pistoia Selected presentation Valeria Poli Selected presentation Sabina Sangaletti Janine Erler 17.45 - 18.30 Plenary Lecture Alberto Mantovani 19.00 - 19.15 Bus Transfer 19.15 - 22.00 Welcome Cocktail Friday September 12th Scientific Programme Venue: POLO CHIMICO BIO MEDICO (Mammut) 08.00 Registration and poster hanging 08.30 - 10.30 Session 2: Non Coding RNAs and Epigenetics 08.30 - 09.00 09.00 - 09.15 09.15 - 09.45 09.45 - 10.00 10.00 - 10.30 George Calin Selected presentation Reuven Agami Selected presentation Clara Nervi 10.30 - 11.00 Coffee Break 11.00 - 13.00 Poster Viewing With Authors 13.00 - 14.00 Light Lunch 7 Friday September 12th Scientific Programme Venue: POLO CHIMICO BIO MEDICO (Mammut) 8 14.00 - 15.30 Poster Discussion (4 parallel sessions) Poster Discussion 1 Poster Discussion 2 Poster Discussion 3 Poster Discussion 4 15.30 - 18.00 Session 3: Cancer Stem Cells 15.30 - 16.00 16.00 - 16.15 16.15 - 16.45 16.45 - 17.00 Ruggero De Maria Selected presentation Christopher Heeschen Selected presentation 17.00 - 17.30 Coffee Break 17.30 - 18.00 Pier Paolo Di Fiore 18.15 - 19.15 SIC General Assembly 20.15 Social Dinner Room E2 Room E3 Room D6 Room D7 Saturday September 13th Scientific Programme Venue: POLO CHIMICO BIO MEDICO (Mammut) 08.30 - 09.15 Plenary Lecture Guido Kroemer 09.15 - 11.30 Session 4: “Translational” Therapy 09.15 - 09.45 09.45 - 10.15 10.15 - 10.45 10.45 - 11.30 Giampaolo Tortora Brunangelo Falini Nicola Normanno Companies lectures 11.30 - 12.30 Award Ceremony 12.30 - 13.30 Light Lunch 13.30 - 14.15 Giorgio Prodi Lecture Pier Giuseppe Pelicci 14.15 - 15.45 Session 5: Translational Diagnostics: NGS, Circulating Cells\Nucleic Acids 14.15 - 14.45 14.45 - 15.00 15.00 - 15.30 15.30 - 15.45 Simon Joosse Selected presentation James Brenton Selected presentation 15.45 - 16.30 Closing Lecture Pier Paolo Pandolfi 16.30 - 17.00 Closing Remarks 9 Scientific Information CME CREDITS The Scientific Programme of the 56th Annual Meeting of the Italian Cancer Society has been credited by the Italian Ministry of Health for the following Professions and Disciplines: Profession: Medical Surgeon (Disciplines: Haematology, Medical Genetics, Pathological Anatomy, Pharmacology and Clinical Toxicology, Clinical Pathology, Internal Medicine); Biologist, Pharmacist, Chemist (Discipline: Analytical Chemistry); Physicist (Discipline: Health Physics); Veterinary Surgeon. ABSTRACT SUBMISSION The organizers invite authors to submit abstracts to be considered and included in the programme. Abstracts written in English must not exceed 2500 characters including blanks. Abstract submission link is available at www.csccongressi.it. Abstracts must focus on the following topics: • In vivo models of cancer • Autophagy, apoptosis, necrosis and senescence • Cancer genetics • Cancer modeling and imaging • Cancer stem cells • Cell adhesion, migration, invasion and metastasis • Cell metabolism • Cell cycle regulation • Control of gene expression and epigenetics • DNA damage and molecular responses to damage • Drug resistance • Infectious agents and cancer • Innovative therapeutic • Molecular epidemiology and chemoprevention • Molecular markers of diagnosis, prognosis and response to therapy • Nanotechnology • Non-coding RNAs • Signal transduction and intracellular trafficking • System biology and emerging technologies • Targeted therapy • Tumor immunology and immunotherapy • Tumor microenvironment: inflammation, hypoxia and angiogenesis Deadline For Abstract Submission: May 5th, 2014 10 The Scientific Committee will select the abstracts for: • oral presentation • poster presentation (70w x 100h cm) Notification of acceptance for presentation or rejection, together with information about session, date and time of discussion, will be sent by the organizing secretariat by e-mail. Please note: each Author can present only one abstract. Abstracts will be included in the programme and in the abstract book only if the presenting Author has registered in the Congress. SLIDES Slides must be in English. Computer videoprojection will be available in Power Point. Please communicate to the Organizing Secretariat your different requirements as soon as possible. Slides has to be handle to the slide centre one hour before the session beginning. Scientific Information USEFULL INFORMATION FROM SIC PRIZES The application for the following Prizes has to be sent to SIC Secretariat via e-mail [email protected]. . Announcement and application will be published on the web site www.cancerologia.it For any information about the Prizes please contact SIC Secretariat. All prizes will be awarded, on the basis of a merit ranking, on September 13th 2014, during the Award Ceremony “Piero Trivella” Prize to the best poster The Associazione Oncologica Pisana “Prof. Piero Trivella” will award the best poster. To apply it is necessary to: • Be SIC Member • Be first author of the submitted abstract (copy of the abstract must be attached) • Be regularly registered in the Meeting • Be younger than 35 years at the date of the Meeting (copy of the identity card must be attached) Those who wish to apply for the prize must present their poster at the Meeting even in case their abstract has been selected as oral presentation. Should the winner not be present at the Award Ceremony, the prize will be awarded following the ranking order. The application must be sent by May 30, 2014 “Elena Cappannini” Prize to the best 2013 publication as first author in innovative approaches for cancer treatments To apply for this prize in memory of Elena Cappannini it is necessary to: • Be first author of the publication in the field of preclinical or clinical innovative approaches for cancer treatment published in 2013 (copy of the paper and CV must be attached) • Be younger than 40 years at the date of the Meeting (copy of the identity card must be attached) The application must be sent by May 30, 2014 Scholarship “Pezcoller Foundation - Ferruccio and Elena Bernardi” In memory of Ferruccio and Elena Bernardi, financed by the Pezcoller Foundation and with the organizational support of SIC, a scholarship will be awarded to a young researcher, Italian citizen, graduated in Biomedical Sciences or similar who wishes to improve his/her already achieved and proved experience in the field of cancer research. The scholarship amounts to Euro 25.000,00/year, including taxes as per the Italian law, and lasts one year starting from January 1, 2015; it can be extended for one more year upon availability of the Foundation and upon evaluation of the activity performed by the researcher. The application must be sent by May 15, 2014. Travel Grants A limited number of Travel Grants can be awarded upon financial availability. To apply for Travel Grants it is necessary to: • Be SIC Member • Be first author of the submitted abstract (copy of the abstract must be attached) • Be regularly registered in the Meeting • Be younger than 35 years at the date of the Meeting (copy of the identity card must be attached) The application must be sent by May 30, 2014. 11 General Information DATES Ferrara 11th -13th September 2014 CONGRESS VENUE Università degli Studi di Ferrara - Via Luigi Borsari, 46 - 44121 Ferrara OPENING CEREMONY VENUE Azienda Ospedaliero Universitaria di Ferrara Arcispedale Sant’Anna - Via Aldo Moro, 8 - 44124 Cona – Ferrara SIC SECRETARIAT Società Italiana di Cancerologia Via G. Venezian, 1 - 20133 Milan, Italy Phone +39 02 2666895 - Fax +39 02 2664342 E-mail: [email protected] www.cancerologia.it ORGANIZING SECRETARIAT C.S.C. S.r.l. Via L.S. Gualtieri, 11 - 06123 Perugia Tel+390755730617 - Fax +390755730619 www.csccongressi.it OFFICIAL LANGUAGE English. Simultaneous translation will not be provided. BADGE Participants and exhibitors are kindly request to wear their badge during the congress. CERTIFICATE OF ATTENDANCE Certificate of attendance is given to all registered participant at the end of the congress. EXHIBITION AND SPONSORSHIP A technical, pharmaceutical and publication exhibition will be held in the Congress Venue. For any information please contact the Organizing Secretariat. 12 General Information REGISTRATION FEE SIC MEMBER By 21/06 € 330,00 By 23/08 € 380,00 On site € 420,00 NON SIC MEMBER € 430,00 € 480,00 € 520,00 SIC MEMBER UNDER 35 € 190,00 € 240,00 € 260,00 NON SIC MEMBER UNDER 35 € 250,00 € 310,00 € 335,00 VAT 22% Included. Registration Fee Includes: Admission to the scientific sessions, admission to the exhibit area, congress kit abstract book, attendance certificate, welcome cocktail, coffee-breaks, light lunches and social dinner. Online registration available at www.csccongressi.it PAYMENT Payment online: by bank transfer or credit card data collection Payment on site: by cash or credit card (accepted VISA and MASTERCARD) CANCELLATION In case of cancellation no reimbursement is foreseen. HOUSING The Organizing Secretariat has reserved rooms in 3 and 4 stars Hotel in Ferrara at special rates. We suggest you to book as soon as possible to have the special rates guaranteed. Hotel booking available at www.csccongressi.it. Deadlines Abstract submission Early registration fee Late registration fee Early hotel booking Late hotel booking 5th May 2014 21st June 2014 23rd August 2014 - - “Piero Trivella” Prize Travel Grants “Elena Cappannini” Prize Scholarship “Pezcoller Foundation Ferruccio and Elena Bernardi” 30th May, 2014 30th May, 2014 30th May, 2014 15th May, 2014 13 General Information Congress Venue HOW TO REACH THE CONGRESS VENUES By Car Motorway A13, exit Ferrara South Parking area: • Inside the “MAMMUT” (entrance 1) • Inside the ex-hospital St. Anna (entrance 3) • Along the Rampari of San Rocco or Fossato di Mortara (toll parking - 2,00 Euros for the entire day) By train Ferrara stop From the station to the congress venue: • by taxi •bus N. 1 Rampari San Rocco stop, in front of the MAMMUT 14 By plane From Bologna Marconi Airport to Ferrara Shuttle “BUS & FLY” (Time: 60 minutes. Cost: 15,00 Euros). It stops in the city center and at the train station. Walking From the city center 15 min walking distance By bus bus N. 1 Rampari San Rocco stop, in front of the MAMMUT General Information Opening Day Venue HOW TO REACH THE OPENING DAY VENUE By Car Motorway A13, exit Ferrara South Then proceed straight for about 10 km on the highway RA8 (Raccordo Ferrara-Mare) to the exit Cona Parking area: in the free parking lots of the hospital By bus bus n. 6, starting at various bus stops in from center city every 15 minutes. It stops right in front of the Conference Hall 15 16