ELENCO DELLE PUBBLICAZIONI SCIENTIFICHE DEL PROF. FRANCO COZZI (censite in PUBMED, SCOPUS e/o WEB OF KNOWLEDGE) 1. Cozzi F, Fiocco U, Pannunzio MT, Gambari PF, Todesco S. Effetto precoce del levamisolo sulle immunoglobuline plasmatiche nell’artrite reumatoide. Boll Soc It Biol Sper 1980;56:481-4. 2. Cozzi F, Ruffatti A, Dalla Santa G, Dal Molin I, Fiocco U, Todesco S. Gli autoanticorpi antitissutali durante la terapia con levamisolo nell'artrite reumatoide. Boll Soc It Biol Sper 1982;58: 407-11. 3. Fagiolo U, Corsano A, Cozzi F, Mauro A, Baricordi RO, Todesco S. Mononuclear subpopulations and autoantibodies reacting with autologous T cells in rheumatoid arthritis and seronegative arthritides. Advances Inflamm Res 1982;3:147-54. IF 1.498. 4. Cozzi F, Fiocco U, Ruffatti A, Tonon R, Todesco S. La terapia dell'artrite reumatoide mediante levamisolo. Clin Ter 1982;102:153-62. 5. Cozzi F, Tessier R, Glorioso S, Peserico A, Todesco S. Electrocardiogram in progressive systemic sclerosis. Analysis of 73 cases. Acta Cardiol 1983;38:27-34. IF 0.556. 6. Bertaglia E, Cozzi F, Belmonte P, Azzurro M, Belloni M, Ongaro G. Short-term effects of plasma exchange on coagulation factors in a sclerodermic patient. Transfusion 1983;23:271-2. IF 4.111. 7. Marson P, Bucci N, Punzi L, Cimino C, Cozzi F, Todesco S. Influenza dei parametri climatici e meteorologici sul dolore articolare nell’artrite reumatoide. Reumatismo1989; 41: 259-266. 8. Targa L, Cardin G, Cozzi F, Glorioso S, Rossi L, Todesco S. I disordini elettrocardiografici nelle diverse varietà cliniche di sclerodermia. G Clin Med 1990;71:17-24. 9. Giusti P, Cima L, Tinello A, Cozzi F, Targa L, Lazzarin P, Todesco S. Stresshormone, freigesetzt durch Fangotherapie. ACTH- und Beta-Endorphin-Konzentrationen unter Wärmestress. Fortsch Med 1990;108:601-4. 10. Marson P, Vicarioto M, Caporale Baffa A, Lazzaro AR, Rosada M, Cozzi F, De Silvestro G. Sierologia anti-epatite C in pazienti con elevate concentrazioni di fattore reumatoide: studio su 50 campioni consecutivi. G Mal Infett Parass 1992; 44: 827-30. 11. Cima L, Cozzi F, Giusti P, Guidetti G, Todesco S. Neuroendocrine effects of a cycle of fangotherapy. Pharmacol Res 1992; 26 (suppl. 1): 302. 12. Cozzi F, Lazzarin P, Tinello A, Cima L, Todesco S. Fangotherapy and bone metabolism. Pharmacol Res 1992; 26 (suppl. 1): 302. 13. Tognon S, Cozzi F, Todesco S, Secchi AG. Lacrimal defects in adult and senile rheumatoid arthritis. Ocular Immunol Inflamm 1993;1:163-6. IF 0.814. 14. Cozzi F, Lazzarin P, Todesco S, Cima L. Hypothalamic-pituitary-adrenal axis dysregulation in healthy subjects undergoing mud-bath applications. Arthritis Rheum 1995;38:724-6. IF 7.232. 1 15. Cozzi F, Cima L, D’Angelo A, Carmignoto F, Grigoriev AI, Todesco S. Modificazioni dell’apparato locomotore in condizioni fisiche estremali (assenza prolungata di gravità nei cosmonauti). Reumatismo 1996; 48:57-62. 16. Cozzi F, Parisi G, Pistorello P, Fanton L, Polito D, Lazzarin P, Todesco S. Studio epidemiologico sulle affezioni dell'apparato locomotore trattate con la fango-balneoterapia nel Bacino Termale Euganeo. Reumatismo 1996; 48: 103-109. 17. Cozzi F, Pistorello GC, Fanton L, Ferron G, Lazzarin P, Todesco S. Effetti a lungo termine della fango-balneoterapia del Bacino Termale Euganeo nella gonartrosi. Med Clin Term 1998; 12: 129-37. 18. Ferri C, Valentini G, Cozzi F, Martini A, Rosada M, Tirri E, Storino FAA, Bullo A, De Luca A, Giuggioli D, Glorioso S, La Montagna G, Michelasi C, Pasero G, Todesco S, Tirri G. Survival study in Italian patients with systemic sclerosis. Arthritis Rheum 1998; 41: S217. 19. Della Rossa A, Valentini G, Bombardieri S, Bencivelli W, Silman AJ, D'Angelo S, Cerinic MM, Belch JF, Black CM, Becvar R, Bruhlman P, Cozzi F, et al. European multicentre study to define disease activity criteria for systemic sclerosis. I. Clinical and epidemiological features of 290 patients from 19 centres. Ann Rheum Dis 2001;60:585-91. IF 3.188. 20. Cozzi F, Chiesura Corona M, Rizzi M, Dus C, Durigon N, Mancin S, Todesco S. La TC polmonare ad alta risoluzione nelle diverse forme cliniche e specificità anticorpali della sclerodermia. Reumatismo 2001;53:55-62. 21. Cozzi F, Marson P, Rosada M, De Silvestro G, Bullo A, Punzi L, Todesco S. Long-term therapy with plasma exchange in systemic sclerosis: effects on laboratory markers reflecting disease activity. Transfus Apheresis Sci 2001;25:25-31. IF 0.984. 22. Ostuni PA, Botsios C, Sfriso P, Semerano L, Grava C, Cozzi F, Todesco S. Mortality and morbility in Italian patients with Sjögren syndrome. J Rheumatol 2001; 28 (suppl. 63): 112. 23. Marson P, Cozzi F, De Silvestro G, Rosada M, Bullo A, Ongaro G, Todesco S. Il trattamento a lungo termine con plasma-exchange nella sclerosi sistemica. La Trasf. del Sangue 2001; 46: 10-6. 24. Ferri C, Valentini G, Cozzi F, Sebastiani M, Michelassi C, La Montagna G, Bullo A, Cazzato M, Tirri E, Storino F, Giuggioli D, Cuomo G, Rosada M, Bombardieri S, Todesco S, Tirri G; Systemic Sclerosis Study Group of the Italian Society of Rheumatology (SIR-GSSSc). Systemic sclerosis: demographic, clinical, and serologic features and survival in 1,012 Italian patients. Medicine (Baltimore). 2002;81:139-53. IF 5.188. 25. Ruffatti A, Sinico RA, Radice A, Ossi E, Cozzi F, Tonello M, Grypiotis P, Todesco S. Autoantibodies to proteinase 3 and myeloperoxidase in systemic sclerosis. J Rheumatol 2002;29:918-23. IF 2.987. 26. Ostuni P, Botsios C, Sfriso P, Bertagnin A, Cozzi F, Doria A, Todesco S. Prevalenza e caratteristiche cliniche della fibromialgia nelle connettiviti maggiori: lupus eritematoso sistemico, sclerosi sistemica e sindrome di Sjogren primitiva. Minerva Med 2002;93: 203-9. 27. Punzi L, Sfriso P, Pianon M, Schiavon F, Ramonda R, Cozzi F, Todesco S. Clinical manifestations and outcome of polyarthralgia associated with chronic lymphocytic thyroiditis. Semin Arthritis Rheum 2002;32:51-5. IF 2.750. 2 28. Cozzi F, Botsios C, Ostuni P, Sfriso P, Piva E, Marson P, Punzi L, Todesco S. Adult HenochSchonlein purpura with glomerulonephritis and paroxysmal nocturnal haemoglobinuria: an uncommon association. Clin Rheumatol 2002;21:408-10. IF 0.976. 29. Del Rosso A, Bertinotti L, Pietrini U, Messori A, Fanciullacci M, Casale R, Giacomelli R, Generini S, Sicuteri R, Pignone A, Cozzi F, Matucci-Cerinic M. Pupillocynetic activity of substance P in systemic sclerosis. J Rheumatol. 2003;30:1231-7. IF 2.674. 30. Cozzi F, Zucchetta P, Durigon N, Marzola MC, Bullo A, Favaro M, Bui F, Todesco S. Alterazioni della peristalsi esofagea nelle diverse forme cliniche e specificità anticorpali della sclerodermia: studio scintigrafico in 100 pazienti. Reumatismo 2003;55:86-92. 31. Cozzi F, Podswiadek M, Cardinale G, Schuller E, Punzi L, Todesco S. Efficacy of mud-bath treatment in spondylitis associated with inflammatory bowel disease. Ann Rheum Dis 2003; 62 (suppl. 1): 244-5. 32. Nava T, Zanetti P, Durigon N, Favaro M, Tiso F, Sfriso P, Cozzi F. Hand rehabilitation in systemic sclerosis: a short-term study of 10 patients. Ann Rheum Dis 2003; 62 (suppl. 1) : 555. 33. Botsios C, Ostuni P, Cozzi F, Punzi L, Rizzo PB, Da Mosto MC, Marchiori C. Systemic sclerosis in a patient with recent nasopharyngeal carcinoma: an unusual combination. Joint Bone Spine 2003;70:396-7. IF 0.869. 34. Botsios C, Ostuni P, Cozzi F, Punzi L, Rizzo PB, Da Mosto MC, Marchiori C. Sclérodermie systémique chez un patient ayant un carcinome nasopharyngien récent: une association inhabituelle. Rev Rhum 2003;70: 779-80. IF 0.869. 35. Grypiotis P, Ruffatti A, Cozzi F, Sinico RA, Tonello M, Radice A, Favaro M, Todesco S. Prevalenza e significato clinico degli anticorpi anti-catepsina G nella sclerosi sistemica. Reumatismo 2003;55:256-62. 36. Cozzi F, Carrara M, Sfriso P, Todesco S, Cima L. Anti-inflammatory effect of mud-bath applications on adjuvant arthritis in rats. Clin Exp Rheumatol 2004;22:763-6. IF 1.504. 37. Grypiotis P, Cozzi F, Ruffatti A. Autoantibodies to bactericidal/permeability-increasing protein and cathepsin G in systemic sclerosis. J Rheumatol 2004;31:1468-9. IF 2.860. 38. Punzi L, Canesi B, Carrabba M, Cimmino MA, Frizziero L, Lapadula G, Arioli G, Chevallard M, Cozzi F, Cricelli C, et al. Consensus italiana sulle raccomandazioni dell’ EULAR 2003 per il trattamento dell’artrosi del ginocchio. Reumatismo 2004;56:190-201. 39. Del Rosso A, Kowal-Bielecka O, Kaloudi O, Orsi S, Stanflin N, Rautia M, Pignone A, Perfetto F, Sierakowski S, Konttinen Y, Cozzi F, Matucci-Cerinic M. Levels of neuropeptides in bronchoalveolar lavage (BAL) fluids of patients with systemic sclerosis. Ann Rheum Dis 2004 ; 63 (suppl 1): 336-7. 40. Cozzi F, Oliviero F, Sfriso P, Baritussio A, Gambaro G, Calabrese F, Ostuni P, Todesco S. Effects of antifibrogenetic agents on bleomycin-induced lung fibrosis. Ann Rheum Dis 2004; 63 (suppl. 1) : 342. 41. Ruffatti A, Favaro M, Cozzi F, Tonello M, Grava C, Lazzarin P, Milanesi O, Marson P, Balboni A, Brucato A. Anti-SSA/Ro related congenital heart block in two family members of different generations. Arthritis Rheum 2005;52:1623-5. IF 7.421. 3 42. Ghirardello A, Zampieri S, Iaccarino L, Tarricone E, Tonello M, Bendo R, Rondinone R, Cozzi F, Doria A. Gli anticorpi miosite specifici e miosite associati nelle miopatie infiammatorie idiopatiche: studio sierologico di 46 pazienti. Reumatismo 2005;57:22-8. 43. Furlan A, Podswiadek M, Cozzi F, Todesco S Tenosinovite delle caviglie come segno d’esordio di sarcoidosi in un paziente con rettocolite ulcerosa. Reumatismo2005; 57: 197200. 44. Cozzi F, Montisci R, Marotta H, Bobbo F, Favaro M, Tiso F, Ciprian L, Iliceto S, Todesco S. Long term treatment with bosentan for pulmonary arterial hypertension related to systemic sclerosis. Ann Rheum Dis 2005; 64 (suppl. 3): 297. 45. Sfriso P, Oliviero F, Cozzi F, Baritussio A, Zoso V, Calabrese F, Todesco S. Heparin, cartopril and dermatansulphate are ineffective in preventing bleomycin-induced lung fibrosis in rats. Ann Rheum Dis 2005; 64 (suppl. 3): 303-4. 46. Botsios C, Fiocco U, Ostuni PA, Vezzù M, Sfriso P, Cozzi F, Schiavon F, Punzi L, Todesco S. Safety of tumor necrosis factor A and inerleukin-1 blocking agents in rheumatoid arthritis patients in clinical practice: 4 years experience with 565 patients in a single academic Italian Center. Ann Rheum Dis 2005; 64 (suppl. 3): 456. 47. Sfriso P, Oliviero F, Calabrese F, Miorin M, Facco M, Contri A, Cabrelle A, Baesso I, Cozzi F, Andretta M, Cassatella MA, Fiocco U, Todesco S, Konttinen YT, Punzi L, Agostini C. Epithelial CXCR3-B regulates chemokines bioavailability in normal, but not in Sjogren's Syndrome, Salivary Glands. J Immunol 2006; 176:2581-9. IF 6.293. 48. Cozzi F, Ostuni PA, Marotta H, Sfriso P, Favaro M, Todesco S. Bosentan may induce arthritis flare in sclerodermia patients concomitantly treated with methotrexate. Ann Rheum Dis 2006; 65: 692-3. IF 5.767. 49. Cozzi F, Marotta H, Pontarollo S, Sarais C, Tiso F, Sfriso P, Iliceto S, Todesco S. Treatment with bosentan of pulmonary hypertension associated with connective tissue diseases: long term results and safety. Ann Rheum Dis 2006 ; 65 (suppl. 2): 387-8. 50. Damjanov NS, Ostojic P, Kaloudi O, Alari S, Cinelli M, Guiducci S, Del Rosso A, Stanflin N, Orsi S, Nestorovic B, Knezevic J, Camiciottoli G, Porta F, Meoni E, Pistolesi M, Conforti M, Cozzi F, Sfriso P, Moggi Pignone A, Matucci-Cerinic M. Induced sputum : a noninvasive tool for evaluation of lung involvement and alveolar inflammation in systemic sclerosis. Ann Rheum Dis 2006 ; 65 (suppl. 2): 388. 51. Sfriso P, Oliviero F, Cozzi F, Miorin M, Facco M, Agostini C, Punzi L. Low levels of CXCL 11 in bronchoalveolar lavage fluid of patients with systemic sclerosis correlate with development of pulmonary fibrosis. Ann Rheum Dis 2006; 65 (suppl. 2): 522. 52. Cozzi F, Montisci R, Marotta H, Bobbo F, Durigon N, Ruscazio M, Sfriso P, Iliceto S, Todesco S. Bosentan therapy of pulmonary arterial hypertension in connective tissue diseases. Eur J Clin Invest 2006; 36: 49-53. IF 2.847. 53. Majone F, Zamboni D, Cozzi F, Montaldi A, Grypiotis P, Luisetto R, Favaro M, Tonello M, Ruffatti A. Unstabilized DNA breaks in lymphocytes of patients with systemic sclerosis. Eur J Dermatol 2006; 16:258-61. IF 0.612. 54. Zulian F, Woo P, Athreya BH, Laxer RM, Medsger TA, Lehman TJ, Matucci-Cerinic M, Martini G, Ravelli A, Cozzi F, Foeldvari I, Ruperto N. The Pediatric Rheumatology European Society/American College of Rheumatology/European League against Rheumatism 4 provisional classification criteria for juvenile systemic sclerosis. Arthritis Rheum 2007; 57: 203-212. IF 7.677. 55. Walker UA, Tyndall A, Cziriàk L, Denton CP, Farge Bancel D, Kowal-Bielecka O, MullerLadner U, Bocelli-Tyndall C, Matucci-Cerinic M and EUSTAR Co-authors (Cozzi F). Clinical risk assessment of organ manifestations in systemic sclerosis – a report from the EULAR Scleroderma Trials and Research (EUSTAR) group data base. Ann Rheum Dis 2007; 66: 754-763. IF 6.411. 56. Majone F, Cozzi F, Tonello M, Olivieri S, Montaldi A, Favaro M, Visentin S, Luisetto R, Ruffatti A. Unstabilized DNA breaks in lymphocytes of patients with different subsets of systemic sclerosis. Ann N Y Acad Scie 2007; 1108:240-8. IF 1.731. 57. Cozzi F, Cella G, Marotta H, Maggiorato G, Oliviero F, Sfriso P, Rizzo M, Tona F, Punzi L. Endothelial cell dysfunction in pulmonary arterial hypertension associated to connective tissue diseases: effects of bosentan. Ann Rheum Dis 2007; 66 (suppl. 2): 205. 58. Fioravanti A, Perpignano G, Tirri G, Cardinale G, Gianniti C, Lanza CE, Loi A, Tirri E, Sfriso P, Cozzi F. Effects of mud-bath treatment on fibromyalgia patients: a randomized clinical trial. Rheumatol Int 2007; 27: 1157-61. IF 1.270. 59. Cozzi F, Podswiadek M, Cardinale G, Oliviero F, Dani L, Sfriso P, Punzi L. Mud-bath treatment in spondylitis associated with inflammatory bowel disease – a pilot randomized clinical trial. Joint Bone Spine 2007; 74: 436-9. IF 1.659. 60. Cozzi F, Podswiadek M, Cardinale G, Oliviero F, Dani L, Sfriso P, Punzi L. Traitment par boue et eau thermals dans la spondylarthrite associée à une entèrocolopathoe inflammatoire: essai Clinique pilote randomise. Rev Rhum 2007; 74: 833-7. IF 1.659. 61. Tiso F, Favaro M, Ciprian L, Cardarelli S, Rizzo M, Tonello M, Ruffati A, Cozzi F. Ulcere digitali in una coorte di 333 pazienti sclerodermici. Reumatismo 2007; 59: 215-220. 62. Fineschi S, Cozzi F, Burger D, Dayer JM, Meroni PL, Chizzolini C. Antifibroblast antibodies detected by cell-based ELISA in systemic sclerosis enhance the collagenolytic activity and matrix metalloproteinase-1 production in dermal fibroblasts. Rheumatology 2007; 46:177985. IF 4.045. 63. Marotta H, Montisci R, Tiso F, Pontarollo S, Rizzo M, Tona F, Iliceto S, Cozzi F. Due anni di terapia con bosentan dell’ipertensione arteriosa polmonare associata a connettiviti sistemiche. Reumatismo 2007; 59:299-303. 64. Codullo V, Cavazzana I, Bonino C, Cozzi F, Del Papa N, Ferri C, Franceschini F, Giacomelli R, Matucci-Cerinic M, Morozzi G, Ruffatti A, Valentini G, Montecucco C. Autoantibody profile of scleroderma renal crisis in Italy. Arthritis Rheum 2008; 58: 559. 65. Fineschi S, Goffin L, Rezzonico R, Cozzi F, Dayer JM, Meroni PL, Chizzolini C. Antifibroblast antibodies in systemic sclerosis induce fibroblasts to produce profibrotic chemokines, with partial exploitation of toll-like receptor. Arthritis Rheum 2008; 58:3913-23. IF 6.787. 66. Walker UA, Tyndall A, Cziriàk L, Denton CP, Farge Bancel D, Kowal-Bielecka O, MullerLadner U, Matucci-Cerinic M and EUSTAR Co-authors (Cozzi F). Geographic variation of disease manifestation in systemic sclerosis – a report from the EULAR Scleroderma Trials and Research (EUSTAR) group data base. Ann Rheum Dis 2009; 68:856-62. IF 7.188. 5 67. Majone F, Olivieri S, Cozzi F, Montaldi A, Tonello M, Visentin MS, Ciprian L, Ruffatti A. Increased apoptosis in circulating lymphocytes cultures of anti-RNA polymerase III positive patients with systemic sclerosis. Rheumatol Int 2009; 29:891-5. IF 1.327. 68. Bassi N, Zampieri S, Ghirardello A, Tonon M, Zen M, Cozzi F, Doria A. Pentraxins, antipentracin antibodies and atherosclerosis. Clin Rev Allergy Immunol 2009; 37:36-43. IF 2.597. 69. Cella G, Vianello F, Cozzi F, Marotta H, Tona F, Saggiorato G, Iqbal O, Fareed J. Effect of Bosentan on Plasma Markers of Endothelial Cell Activity in Patients with Secondary Pulmonary Hypertension Related to Connective Tissue Diseases. J Rheumatol 2009; 36: 7607. IF 3.854. 70. Allanore Y, Meune C, Vonk MC, Airo P, Hachulla E, Caramaschi P, Riemekasten G, Cozzi F, Beretta L, Derk CT, et al. Prevalence and factors associated with left ventricular dysfunction in the EULAR Scleroderma Trial and Research group (EUSTAR) database of systemic sclerosis patients. Ann Rheum Dis 2010; 69: 218-21. IF 8.111. 71. Codullo V, Cavazzana I, Bonino C, Alpini A, Cavagna L, Cozzi F, Del Papa N, Franceschini F, Guiducci S, Morozzi G, Ruffatti A, Ferri C, et al. . Serologic profile and mortality rates of scleroderma renal crisis in Italy. J Rheumatol 2009; 36: 1464-9. IF 3.854. 72. Cozzi F, Marson P. Il trattamento con plasma-exchange delle malattie reumatiche sistemiche, ieri e oggi. Reumatismo 2009; 61: 161-4. 73. Cappelli S, Bellando Randone S, Martinovic D, Tamas MM, Pasalic K, Allanore Y, Mosca M, Talarico R, Opris D, Kiss GC, Tausche A, Cardarelli S, Cozzi F et al. Mixed connective tissue disease (MCTD): one diagnosis, more evolutions. Clin Exp Rheumatol 2009; 27: 728. 74. Cozzi F, Tiso F, Lopatriello S, Ciprian L, Sfriso P, Berto P, Punzi L. The social costs of digital ulcer management in scleroderma patients: an observational Italian pilot study. Joint Bone Spine 2010; 77: 83-4. IF 2.460. 75. Cozzi F, Tiso F, Lopatriello S, Ciprian L, Sfriso P, Berto P, Punzi L. Couts socioéconomiques du traitment des ulcere digitaux chez les patients atteints de sclérodemie systémique: étude pilote d’observation en Italie. Rev Rhum 2010; 77:105-6. IF 2.460. 76. Walker U, Bannert B, Vonk MC, Airò A, Cozzi F, Carreira P, Farge-Bancel D, Allanore Y, Muller-Ladner U, et al. Causes of death in systemic sclerosis – A report from the EUSTAR data base. Clin Exp Rheumatol 2010; 28 (suppl. 58): S83. 77. Miniati I, Valentini G, Cozzi F, Guiducci S, Cuomo G, Vettori S, Bonino C, Ciprian L, Panico N, Matucci-Cerinic M, Cziriak L. Evaluation of skin involvement in SSc patients with modified Rodnan skin score: results of the Italian course. Clin Exp Rheumatol 2010; 28 (suppl. 58): S122. 78. Cappelli S, Bellando Randone S, Martinovic D, Radic M, Tamas MM, Damjanov N, Pasalic K, Allanore Y, Bombardieri S, Cozzi F, Matucci-Cerinic M. Mixed connective tissue disease (MCTD): one diagnosis, more evolutions. Clin Exp Rheumatol 2010; 28 (suppl. 58): S123-4. 79. Degani V, Piovesana P, Pigatto E, D’Ambrosio FD, Cardarelli S, Leone MG, Rizzo M, Scarabeo V, Ciprian L, De Conti F, Cozzi F. Exerxise-induced arterial pulmonary hypertension in systemic sclerosis: an echocardiography study. Clin Exp Rheumatol 2010; 28 (suppl. 58): S128. 6 80. Tyndall A, Bannert B, Vonk M, Airò P, Cozzi F, Carreira PE, Farge Bancel D,Allanore Y, Muller-Ladner U, Distler O, et al. Causes and risk factors for death in systemic sclerosis – A study from the EULAR Scleroderma Trials And Research (EUSTAR) data base. Ann Rheum Dis 2010; 69:1809-15. IF 9.082. 81. Avouac J, Walker U, Tyndall A, Kahan A, Matucci-Cerinic M, Allanore Y, et al. and EUSTAR members (Cozzi F). Characteristics of joint involvement and relationships with systemic inflammation in systemic sclerosis: results from the EULAR Scleroderma Trial and Research Group (EUSTAR) database. J Rheumatol 2010;37:1488-501. IF 3.551. 82. Hügle T, Schuetz P, Daikeler T, Tyndall A, Matucci-Cerinic M, Walker UA, Van Laar JM and EUSTAR members (Cozzi F). Late-onset systemic sclerosis – a systematic survey of the EULAR scleroderma trials and research group database. Rheumatology 2011;50:161-5. IF 4.058. 83. Lunardi F, Balestro E, Nordio B, Cozzi F, Polverosi R, Sfriso P, Braccioni F, Calabrese F. Undifferentiated Connective Tissue Disease presenting with prevalent interstitial lung disease: case report and review of literature. Diagn Pathol 2011; 6: 50. IF 1.638. 84. Cappelli S, Bellando Randone S, Martinovic D, Tamas MM, Pasalic K, Allanore Y, Cozzi F, et al. Autoantibodies and clinical features can predict evolution in patients with MCTD Clin Exp Rheumatol 2011; 29: 187-188.IF 2.148 85. Cappelli S, Bellando Randone S, Martinovic D, Tamas MM, Pasalic K, Allanore Y, Mosca M, Talarico R, Opris D, Kiss GC, Tausche A, Cardarelli S, Cozzi F et al. “To be or not to be”, ten years after: evidence for MCTD as a distinct entity. Semin Arthritis Rheum 2011;41:58998. IF 4.969. 86. Cozzi F, Parisi G, Ciprian L, Bullo A, Cardarelli S, Rizzo M, Sfriso P, Punzi L. Gastric dysmotility after liquid bolus ingestion in systemic sclerosis: an ultrasonographic study. Rheumatol Int 2012; 32:1219-23. IF 1.431. 87. Taraborelli M, Ramoni V, Brucato A, Airò P, Bajocchi G, Bellisai F, Biasi D, Blagojevic J, Canti V, Caporali R, Caramaschi P, Chiarolanza I, Codullo V, Cozzi F, et al. Brief report: successful pregnancies but a higher risk of preterm births in systemic sclerosis: An Italian multicentric study. Arthritis Rheum 2012; 64:1970-7. IF 7.866. 88. Sfriso P, Cozzi F, Oliviero F, Caso F, Cardarelli S, Facco M, Fittà C, Del Rosso A, MatucciCerinic M, Punzi L, Agostini C. CXCL11 in broncoalveolar lavage fluid and pulmonary function decline in systemic sclerosis. Clin Exp Rheumatol 2012; 30:S71-75. IF 2.148. 89. Perin A, Zanatta E, Pigatto E, Carniello S, Cozzi F. Ipovitaminosi D in una popolazione anziana ospedalizzata del Friuli Occidentale.. Reumatismo 2012;64: 166-71. 90. Denton CP, Krieg T, Guillevin L, Schwierin B, Rosenberg D, Silkey M, Zultak M, MatucciCerinic M; DUO Registry investigators (Cozzi F). Demographic, clinical and antibody characteristics of patients with digital ulcers in systemic sclerosis: data from the DUO Registry. Ann Rheum Dis 2012;71:718-21. IF 8.727. 91. Cozzi F, Marson P, Cardarelli S, Favaro M, Tison T, Tonello M, Pigatto E, De Silvestro G, Punzi L, Doria A. Prognosis of scleroderma renal crisis: a long-term observational study. Nephrol Dial Transplant 2012; 27: 4398-403. IF 3.396. 7 92. Cozzi F, Guarnieri G, Zanatta E, Pigatto E, Favaro M, Cardarelli S, Maestrelli P, Punzi L. Capillary blood volume measurement in scleroderma patients submitted to nitric oxid diffusion test. Rheumatology 2012; 51(suppl. 2): 104. 93. Zanatta E, Guarnieri G, Pigatto E, Rizzo M, Campana C, Riato L, Maestrelli P, Cozzi F. Nitric oxid diffusion in patients with SSc. Rheumatology 2012; 51(suppl. 2): 104. 94. Koumakis E, Wipff J, Dieudé P, Ruiz B, Bouaziz M, Revillod L, Guedj M, Distler JH, Matucci-Cerinic M, Humbert M, Riemekasten G, Airo P, Melchers I, Hachulla E, Cusi D, Wichmann HE, Hunzelmann N, Tiev K, Caramaschi P, Diot E, Kowal-Bielecka O, Cuomo G, Walker U, Czirják L, Damjanov N, Lupoli S, Conti C, Müller-Nurasyid M, Müller-Ladner U, Riccieri V, Cracowski JL, Cozzi F, et al. TGFβ receptor gene variants in systemic sclerosisrelated pulmonary arterial hypertension: results from a multicentre EUSTAR study of European Caucasian patients. Ann Rheum Dis 2012;71:1900-3. IF 8.727. 95. Meier FM, Frommer KW, Dinser R, Walker UA, Czirjak L, Denton CP, Allanore Y, Distler O, Riemekasten G, Valentini G, Müller-Ladner U, EUSTAR Co-authors (Cozzi F). Update on the profile of the EUSTAR cohort: an analysis of the EULAR Scleroderma Trials and Research group database. Ann Rheum Dis 2012;71:1355-60. IF 8.727. 96. Cozzi F, Raffeiner B, Ciprian L, Botsios C, Perissinotto E, Rizzo M, Zanatta E, Pigatto E, Punzi L. Clinical effects of mud-bath therapy in patients with psoriatic arthritis treated with TNF-inhibitors.Balnea 2012; 6: 173-174. 97. Ciprian L, Raffeiner B, Grisan E, Beltrame V, Coran A, Zanatta E, Rizzo M, Stramare R, Cozzi F. Effects of mud-bath applications on synovial inflammation evaluated by contrasteenhanced ultrasound (CEUS) in patients with psoriatic arthritis. Balnea 2012; 6: 179-180. 98. Ciprian L, Lo Nigro A, Rizzo M, Gava A, Ramonda R, Punzi L, Cozzi F. The effects of Spa therapy and rehabilitation on patients with ankylosing spondylitis being treated with TNF inhibitors. Rheumatol Int 2013; 33:241-5. IF 2.214. 99. Cozzi F, Pigatto E, Rizzo M, Favaro M, Zanatta E, Cardarelli S, Riato L, Punzi L. Low occurrence of digital ulcers in scleroderma patients treated with bosentan for pulmonary arterial hypertension: a retrospective case-control study. Clin Rheumatol 2013;32:679-83. IF 2.037. 100. Caso F, Costa L, Atteno M, Sfriso P, Cozzi F, Cantarini L, Scarpa R, Punzi L. The potential role of bone scintigraphy in the detection of deep muscular fascia involvement and calcinosis cutis in anti-synthetase syndrome. Int J Rheum Dis 2013;16:495-6. IF 1.650. 101. Guillevin L, Hunsche E, Denton CP, Krieg T, Schwierin B, Rosenberg D, Matucci Cerinic M; DUO Registry Group (Cozzi F). Functional impairment of systemic scleroderma patients with digital ulcerations: results from the DUO Registry. Clin Exp Rheumatol 2013; 31(2 Suppl 76):71-80. IF 2.655. 102. Maurer B, Graf N, Michel BA, Müller-Ladner U, Czirják L, Denton CP, Tyndall A, Metzig C, Lanius V, Khanna D, Distler O; EUSTAR co-authors (Cozzi F). Prediction of worsening of skin fibrosis in patients with diffuse cutaneous systemic sclerosis using the EUSTAR database. Ann Rheum Dis 2014; Jun 30 [Epub ahead of print]. IF 9.111. 8 103. Avouac J, Walker UA, Hachulla E, Riemekasten G, Cuomo G, Carreira PE, Caramaschi P, Ananieva LP, Matucci-Cerinic M, Czirjak L, Denton C, Müller-Ladner A, Allanore Y, and EUSTAR collaborators (Cozzi F). Joint and tendon involvement predict disease progression in systemic sclerosis: a EUSTAR prospective study. Ann Rheum Dis 2014; Aug 27[Epub ahead of print]. IF 9.111. 104. Elhai M, Avouac J, Walker UA, Matucci-Cerinic M, Riemekasten G, Airò P, Hachulla E, Valentini G, Carreira PE, Cozzi F, Balbir Gurman A, et al. A gender gap in primary and secondary heart dysfunctions in systemic sclerosis: a EUSTAR prospective study. Ann Rheum Dis. 2014 Oct 23 [Epub ahead of print]. IF 9.111. 105. Bourji K, Gatto M, Cozzi F, Doria A, Punzi L. Rheumatic and Autoimmune Thyroid Disorders: A Causal or Casual Relationship? Autoimmun Rev. 2014; 14: 57-63. IF 7.095. 106. Mihai C, Landewé R, Van der Heijde D, Walker UA, Constantinescu P, Gherghe AM, Ionescu RM, Rednic S , Allanore Y, Avouac J, Czirjak L, Hachulla E, Riemekasten G, Cozzi F, Airò P, Tyndall A, Cutolo M, Müller-Ladner U, Matucci-Cerinic M and EUSTAR coauthors. Digital ulcers predict a worse disease course in systemic sclerosis patients. Ann Rheum Dis 2015 Feb 16 [Epub ahead of print]. IF 9.111. 107. Cozzi F, Raffeiner B, Beltrame V, Ciprian L, Coran A, Botsios C, Perissinotto E, Grisan E, Ramonda R, Oliviero F, Stramare R, Punzi L. Effects of mud-bath therapy on synovial inflammation assessed by contrast-enhanced ultrasound (CEUS) in patients with psoriatic arthritis treated with TNF inhibitors. Joint Bone Spine 2015; 82: 104-8. IF 3.218. 108. Pigatto E, Peluso D, Zanatta E, Polito P, Miatton P, Bourji K, Badano L.P., Punzi L, Cozzi F. Evaluation of right-ventricular function performed by 3d-echocardiography in scleroderma patients. Reumatismo 2014; 66: 259-263. 109. Guarnieri G, Zanatta E, Mason P, Scarpa MC, Pigatto E, Maestrelli P, Cozzi F. Determinants of impairment in lung diffusing capacity in patients with systemic sclerosis. Clin Exp Rheumatol 2015 Apr 16. [Epub ahead of print] IF 2.724. 110. Bourji K, Meyer A, Chatelus E, Pincemail J, Pigatto E, Defraigne JO, Singh F, Charlier C, Geny B, Gottenberg JE, Punzi L, Cozzi F, Sibilia J.. High reactive oxygen species in fibrotic and non-fibrotic skin of Patients with diffuse cutaneous systemic sclerosis. Free Radic Biol Med. 2015; 87: 282-289. IF 5.736. 111. Cozzi F, Raffeiner B, Beltrame V, Ciprian L, Coran A, Botsios C, Perissinotto E, Grisan E, Ramonda R, Oliviero F, Stramare R, Punzi L. Effets du traitement par les bains de boue dans le rhumatisme psoriasique chez les patients traités par anti-TNF. Évaluation clinique et par échographie de contraste de l’inflammation synoviale. Rev Rhum 2015; 82: 236-40. IF 2.901. 112. Wirz EG, Jaeger VK, Allanore Y, Riemekasten G, Hachulla E, Distler O, Airò P, Carreira PE, Tikly M, Vettori S, Balbir Gurman A, Damjanov N, Müller-Ladner U, Distler J, Li M, Häusermann P, Walker UA; EUSTAR coauthors (Cozzi F). Incidence and predictors of cutaneous manifestations during the early course of systemic sclerosis: a 10-year longitudinal study from the EUSTAR database. Ann Rheum Dis. 2015 Jul 31 [Epub ahead of print]. IF 10.377. 113. Cozzi F, Marson P, Pigatto E, Tison T, Polito P, Galozzi P, De Silvestro G, Punzi L. Plasmaexchange as a "rescue therapy" for dermato/polymyositis in acute phase. Experience in three young patients. Transfus Apher Sci. 2015 Aug 7. IF 0.768. 9