Key Dates: 30 June 2011 - Abstract submission 15 July 2011 - Notification of final acceptance of papers 15 July 2011 - Deadline for early bid registration Registration Meeting registration is only available via e-mail to [email protected] Abstracts must be submitted via e-mail as attachments to: [email protected]. The attachment should be a Microsoft Word document. Faxed abstracts will not be considered. Please read the rules of submission before submitting your abstract. At least one of the author must be registered at the meeting. Rules for submission to the 2011 AISAL Congress: AISAL Associazione Italiana per le Scienze degli Animali da Laboratorio FELASA Constituent Association Abstract Title: Abstract must have a short, specific title (containing no abbreviations) that indicates the nature of the research. Author Name(s): The name of presenting author should be underlined. Any abstract changes will not be permitted after July 15, 2011. Abstracts should be in English. Biomaterials in medicine and animal models Abstract Text: ICSU satellite meeting supported by: In the abstract text the research objectives, methods, results and conclusion should be briefly summarized. References and grant support shouldn’t be included. Registration fees: Before After 15 15 July July 2011 2011 Standard registration AISAL member Student * € 150 € 200 € 100 € 150 € 20 € 50 * Evidence of student status, such as copy of official Abstracts are limited to 2,500 characters, excluding the abstract title, and author names. Punctuation marks and spaces count as characters. Tables/graphics and figures shouldn’t be included. Accepted abstracts will be published online in Comparative Medicine (I.F.1.094;http://www.aalas.org/publications/ index.aspx#cm), as well as on the AISAL website. Scientific awards Università di Napoli Federico II AISAL awards two prizes for Young Scientists, one for the best oral presentation and one for the best poster. These prizes are reserved to AISAL members aged 35 years or younger. For both prizes the first author will be awarded. Both awards will be presented at the Closing Ceremony of the Congress. The papers will be judged and ranked by the Scientific Committee. The winner will be awarded with an individual certificate and: enrollment letter, has to accompany registration. Registration fees cover: - All sessions of the scientific program. - Scientific proceedings. - Meeting bag and contents. - Coffee breaks and lunches. 500€ for the best poster 1000 € for the best oral presentation contribution September 22-23, 2011 Congress Center University of Naples Federico II Via Partenope, 36 NAPLES Biomaterials in medicine and animal models A biomaterial is any kind of material that interacts with biological systems, and can be used to treat, enhance or replace any tissue, organ or function in an organism. Biomaterials also refers to biologically-derived materials used for their structural rather than biological properties, e.g. collagen (a protein found in the skin, connective tissues and bone) as a cosmetic ingredient. Also, carbohydrates (biotechnologically modified) are being used as lubricants for biomedical applications and as bulking agents in the food industry. Biomaterials are required to act harmoniously Invited Speakers: Polymer based biomaterials for tissue regeneration. Luigi Ambrosio Institute for Composite and Biomedical Materials, National Research Council, Napoli DegraPol®: Life-sustaining Polymeric Material Eliana Bonavoglia Ab Medica, Milano when exposed to the body or bodily fluids. Investigating cellular or in vivo phenotypic responses helps to determine the associated biocompatibility. Biocompatibility is the use or design of a material harmless to the host tissue, achieved either with chemical and biological inertness or successful integration with the surrounding proteins and cells. A material that is considered biocompatible will have extensive applications in human health care, which could improve a patient’s quality of life and elongate life expectancy. The goal of the in vivo assessment of biocompatibility is to predict whether a medical device presents potential harm to the patient or user by evaluation under conditions simulating clinical use. For the in vivo assessment of biomaterials, medical devices in their final form and condition are commonly implanted in carefully selected animal models to determine function as well as biocompatibility. The main in vivo tests for biocompatibility are: sensitization, irritation, intracutaneous reactivity, systemic toxicity (acute toxicity), subchronic toxicity (subacute toxicity), genotoxicity, implantation, hemocompatibility, chronic toxicity, carcinogenicity, reproductive and developmental toxicity, biodegradation, immune responses. It is clear that the animal models are key to in vivo testing, and furthermore , experimental design of the animal tests must enable reproducible and accurate outcome data that can be quantified. The aim of this meeting is to update and share the latest developments regarding the contribution of animal models in the development of biomaterials with attention to new frontiers on biomaterials, animal models (criteria of selection and description of newly models), how the actual researches can push the clinical innovations, and the ethical and legislative aspects. Regenerative therapy in veterinary medicine: from bench to patient. An overview. Maurizio Del Bue University of Parma Biotechnology and animal ethics: between anthropocentrism and pathocentrism. Kris Dierickx Centre for Biomedical Ethics and Law, Katholieke Universiteit Leuven Preclinical models to evaluate biomaterials for orthopaedic applications. Roberto Giardino Laboratory of Preclinical and Surgical Studies, Rizzoli Orthopaedic Institute, Bologna From mice to men - the relevance of animal models for bone research. Anita Ignatius Institute of Orthopaedic Research and Biomechanics, University of Ulm Animal welfare requirements for biomaterial research. Lucia Martini Rizzoli Orthopaedic Institute, Bologna Cardiovascular regenerative medicine in a smallanimal model of acute myocardial infarction. Carlo Ventura Alma Mater Studiorum, University of Bologna Scientific Committee: Luigi Ambrosio, National Research Council Gianni Dal Negro, GlaxoSmithKline Paolo de Girolamo, University of Naples Federico II Roberto Di Lauro, Zoological Station A. Dohrn, University of Naples Federico II Barbara Dozza, Rizzoli Orthopaedic Institute, Bologna Alessandro Fioretti, University of Naples Federico II Enrico Lucarelli, Rizzoli Orthopaedic Institute, Bologna Paolo Netti, University of Naples Federico II Organizing Committee: Andrea Affuso, Biogem, Ariano Irpino Marcello Raspa, CNR-IBC-EMMA, Monterotondo Andrea Tamellini, Aptuit, Verona Valentina Vasina, University of Bologna "Alma Mater Studiorum" Scientific and organizing secretary: Laura De Francesco, Guido Bernardini Foundation, Milano Valentina Vasina, University of Bologna "Alma Mater Studiorum"