Heads of the Medici Cosimo de' Medici Piero I de' Medici Lorenzo I de' Medici Piero II de' Medici Elected to Papacy Cardinal Giovanni de' Medici Pope Leo X Giulio de’ Medici Pope Clement VII. Giovanni Angelo Medici Pope Pius IV Alessandro Ottaviano de' Medici Pope Leo XI Duke of Florence/Tuscany Alessandro de' Medici, Duke of Florence Cosimo I de' Medici, Grand Duke of Tuscany Francesco I de' Medici, Grand Duke of Tuscany Queen of France Catherine de' Medici Marie de’ Medici The Medici Bank “God’s Bankers” The Medici Bank created in Florence during the 15th century Most profitable business in Europe Partnership with the Catholic Church Collected 10% of earnings for the church Filippo Brunelleschi Cosimo's patronage enabled architect Filippo Brunelleschi to complete the dome of the Florence Cathedral Invention of linear perspective