Director of the Centre:
Prof. Antonino Zichichi
Directors of the Course:
Prof. Mario Barbagallo (University of Palermo, Italy)
Lodovico Balducci (University of South Florida, Tampa, FL, USA)
Mario Belvedere (University of Palermo, Italy)
Roberto Bernabei (University of Rome, Italy)
Luigi Ferrucci (NIH LBSA, Baltimore, MD, USA)
Sponsored by:
Italian ministry of health
Italian ministry of education
Italian ministry of university and scientific research
Italian society of gerontology and Geriatrics
international association of gerontology
sicilian regional government
RELATORI E MODERATORI
FACULTY
Pasquale Abete (University of Naples, Italy)
Tamara Harris (NIA, Bethesda, MD, USA)
Umberto Alecci (Messina, Italy)
Giancarlo Isaia (University of Turin, Italy)
Dawn Alley (University of Pennsylvania, Philadelphia, PA, USA )
Giuseppe Licata (University of Palermo, Italy)
Raffaele Antonelli Incalzi (Campus Bio-Medico, Univer-
Domenico Lio (University of Palermo, Italy)
sity of Rome, Italy)
Stefania Maggi (Padua, Italy)
Maurizio Averna (University of Palermo, Italy)
Mariano Malaguarnera (University of Catania, Italy)
Lodovico Balducci (University of South Florida, Tampa, FL, USA)
Niccolò Marchionni (University of Florence, Italy)
Stefania Bandinelli (INRCA, Florence, Italy)
Domenico Maugeri (University of Catania, Italy)
Carlo M.Barbagallo (University of Palermo, Italy)
Patrizia Mecocci (University of Perugia, Italy)
Mario Barbagallo (University of Palermo, Italy)
Vito Milazzo (Trapani, Italy)
Giuseppe Barbagallo (Nicosia, Italy)
Letterio Morgante (University of Messina, Italy)
Jean-Pierre Baeyens (University of Oostende, Belgium)
John E. Morley (University of Saint Louis, MO, USA)
Claudia Beghè (VA, Tampa, FL, USA)
Anne Newman (University of Pittsburgh, PA, USA)
Vincenzo Bellia (University of Palermo, Italy)
Vittorio Nicita-Mauro (University of Messina, Italy)
Mario Belvedere (University of Palermo, Italy)
Alberto Notarbartolo (University of Palermo, Italy)
Roberto Bernabei (University of Rome, Italy)
Salvatore Novo (University of Palermo, Italy)
Maurizio Bevilacqua (Osp. Sacco, Milan, Italy)
Patrizio Odetti (University of Genoa, Italy)
Sante Branca (Catania, Italy)
Gioacchino Oddo (Palermo, Italy)
Giuseppina Candore (University of Palermo, Italy)
Michele Pagano (Palermo, Italy)
Carlo Cannella (University of Rome, Italy)
Marco Pahor (University of Florida, Gainesville, FL, USA)
Calogero Caruso (University of Palermo, Italy)
Giuseppe Paolisso (Second University of Naples-SUN, Italy )
Pierpaolo Ceda (University of Parma, Italy)
Mario Passeri (University of Parma, Italy)
Antonio Cherubini (University of Perugia, Italy)
Ian Philp (University of Sheffield, UK)
Giuseppina Colonna-Romano (University of Palermo, Italy)
Ernesto Putignano (University of Palermo, Italy)
Francesco Corica (University of Messina, Italy)
Suresh Rattan (University of Aarhus, Denmark)
Giuseppe Costanza (University of Palermo, Italy)
Franco Rengo (University of Naples, Italy)
Domenico Cucinotta (Osp. Villa Laura, Bologna, Italy)
Giovam Battista Rini (University of Palermo, Italy)
Ligia J. Dominguez (University of Palermo, Italy)
Giuseppe Rotolo (University of Palermo, Italy)
Lorenzo M Donini (University of Rome, Italy)
Michelangelo Sapienza (Palermo, Italy)
William J Evans (University of Arkansas, AK, USA)
Giovanni Savettieri (University of Palermo, Italy)
Nicola Ferrara (University of Molise, Italy)
Roberto Sega (University of Milan, Italy)
Luigi Ferrucci (NIH LBSA, Baltimore, MD, USA)
Luigi Spicola (Palermo, Italy)
Giovanni Fradà (University of Palermo, Italy)
Stephanie Studenski (University of Pittsburg, PA, USA)
Claudio Franceschi (University of Bologna, Italy)
Eva Topinkova (University of Prague, CZ)
Luigi Galvano (Palermo, Italy)
Marco Trabucchi (University of Rome/Brescia, Italy)
Giovanni Gambassi (University of Rome, Italy)
Marjolen Visser (VU University Med. Ctr, Amsterdam, NL)
Fernando Gomez (University of Caldas, Manizales, Colombia)
Mauro Zamboni (University of Verona, Italy)
Jack Guralnik (NIH, Bethesda, MD, USA)
Mario Zappia (University of Catania, Italy)
October 23 (Tuesday)
Morning
Genetics and Biology of Aging - Genetica e Biologia dell’Invecchiamento
First Session
Chairmen
Mario Barbagallo (University of Palermo, Italy)
Calogero Caruso (University of Palermo, Italy)
09.30 a.m.
Claudio Franceschi (University of Bologna, Italy)
An evolutionary approach to longevity
Un approccio evoluzionistico alla longevità
10.00 a.m.
Calogero Caruso (University of Palermo, Italy)
Genetics of cardiovascular disesase and longevity
Genetica delle malattie cardiovascolari e longevità
10.30 a.m.
Suresh Rattan (University of Aarhus, Denmark)
Hormesis and longevity
Ormesi e longevità
11.00- 11.15 a.m. Coffee Break
Second Session
Chairmen
Giovanni Fradà (University of Palermo, Italy)
Calogero Caruso (University of Palermo, Italy)
11.15 a.m.
Giuseppina Candore (University of Palermo, Italy)
Inflammation, aging and longevity
Infiammazione, invecchiamento e longevità
11.30 a.m.
Giuseppina Colonna-Romano (University of Palermo, Italy)
Immunity, aging and longevity
Immunità, invecchiamento e longevità
11.45 a.m.
Domenico Lio (University of Palermo, Italy)
Identification of a risk profile for unsuccessful aging
Identificazione di un profilo di rischio per un invecchiamento “non” di successo
12.00 a.m.
General Discussion
Lunch
October 23 (Tuesday)
Afternoon
16.30 p.m.
Opening Ceremony and Welcoming Addresses
Inaugurazione e Saluto dei Direttori del Corso e delle Autorità
Plenary Lectures
Roberto Bernabei (University of Rome, Italy)
Third generation geriatric assessment
L’Assessment geriatrico di terza generazione
Lodovico Balducci (University of South Florida, Tampa, FL, USA)
Cancer and aging
Neoplasie e invecchiamento
Adjourn
October 24 (Wednesday)
Morning
The lifetime roots of sarcopenic obesity
Le radici della obesità sarcopenica nel corso della vita
First Session
Chairmen
Luigi Ferrucci (NIH LBSA, Baltimore, MD, USA)
Mario Barbagallo (University of Palermo, Italy)
09.00 a.m.
William J Evans (University of Arkansas, AK, USA)
Is fatness a risk factor for bad health outcomes if it is not associated with sarcopenia?
L’obesità è un fattore di rischio se non è associata a sarcopenia?
09.30 a.m.
Tamara Harris (National Institute on Aging, Bethesda, MD, USA)
Which is more closely related to disability and death in old age-current weight or weight earlier
in life?
Cosa è maggiormente correlato alla disabilità ed alla morte in tarda età- il peso attuale o il peso
nelle età precedenti della vita?
10.00 a.m.
Dawn Alley (University of Pennsylvania, Philadelphia, PA, USA )
Which trajectories of weight change over the lifetime are associated with health outcomes?
Quali traiettorie delle modificazioni del peso nel corso della vita sono maggiormente associate
con gli outcomes di salute?
10.30 a.m. Coffee Break
Second Session
11.00 a.m.
Luigi Ferrucci (NIH LBSA, Baltimore, MD, USA)
Do obesity in young and the body composition changes of aging have the same metabolic and
functional correlates and consequences?
La obesità nei giovani e le modificazioni della composizione corporea con l’età hanno le stesse
conseguenze metaboliche e funzionali?
11.30 a.m.
Stephanie Studenski (University of Pittsburgh, PA, USA)
Wich is more important - the amount of muscle or strength - if women have more disability, why
do men have more sarcopenia?
Cosa è più importante - la massa muscolare o la forza - se le donne hanno più disabilità, perchè
gli uomini hanno più sarcopenia?
12.00 a.m.
John E. Morley (University of Saint Louis, MO, USA)
Which are the critical periods for selected hormones and cytokines in old age?
Quali sono i periodi critici per ormoni e citochine nelle età avanzate?
12.30 p.m.
General Discussion
1.00p.m to 3.00 p.m. Lunch
October 24 (Wednesday)
Afternoon
First Session
Chairmen
Luigi Ferrucci (NIH LBSA, Baltimore, MD, USA)
John E. Morley (University of Saint Louis, MO, USA)
03.00 p.m.
Stefania Bandinelli (INRCA, Florence, Italy)
Do osteoporosis and sarcopenia have similar or different roots and consequences?
Osteoporosi e sarcopenia hanno radici e conseguenze simili o differenti?
03.30 p.m.
Anne Newman (University of Pittsburgh, PA, USA)
What interventions have been effective in addressing optimal body composition in old age? Is
there a critical role for movement?
Quali interventi sono maggiormente efficaci per ottenere una composizione corporea ottimale
nelle età avanzate? Il movimento ha un ruolo cruciale?
04.00 p.m.
Marjolen Visser (VU University Med. Ctr, Amsterdam, NL)
How (changes in) physical activity may influence both body composition and health outcomes
in old age. Is sarcopenic obesity just an indicator of physical inactivity?
Come la attività fisica può influenzare sia la composizione corporea che gli outcomes di salute
nelle età avanzate. La obesità sarcopenica è solo un indicatore di inattività fisica?
04.25 p.m.
Mauro Zamboni (University of Verona, Italy)
Is there any difference in the activity of adipocytes between older and younger subjects? Which
is the contribution of adipokines to age-related metabolic disorders and to sarcopenia?
C’e differenza nella attività degli adipociti tra soggetti giovani ed anziani? Quale è il contributo
delle adipochine alle alterazioni metaboliche età-correlate ed alla sarcopenia?
04.45 p.m. Coffee Break
Second Session
Anemia in the Elderly - Anemia nell’Anziano
Chairmen
Luigi Ferrucci (NIH LBSA, Baltimore, MD, USA)
Lodovico Balducci (University of South Florida, Tampa, FL, USA)
05.00 p.m.
Lodovico Balducci (University of South Florida, Tampa, FL, USA)
A systematic approach to anemia of the erderly
Un approccio sistematico alla anemia nell’anziano
05.30 p.m.
Jack Guralnik (NIH, Bethesda, MD, USA)
Functional consequences of the anemia of the Elderly
Conseguenze funzionali della anemia nell’anziano
General Discussion
Adjourn
October 25 (Thursday)
Morning
Round Table on
Geriatric Assistance as a Planetary Emergency
Assistenza Geriatrica come Emergenza Planetaria
First Session
Chairmen
Ian Philp (University of Sheffield, UK)
Mario Barbagallo (University of Palermo, Italy)
09.00 a.m.
Ian Philp (University of Sheffield, UK)
A recipe for care
Una ricetta per la cura
09.30 a.m.
Eva Topinkova (University of Prague, CZ)
How to promote geriatrics and incorporate it into the clinical practice, research and health care systems
Come promuovere la geriatria nella pratica clinica, nella ricerca e nei sistemi sanitari
10.00 a.m.
Jean-Pierre Baeyens (Oostende, Belgium)
The present and future of geriatrics in Europe
Il presente ed il futuro della geriatria in Europa
10.30 a.m. Coffee Break
Second Session
11.00 a.m.
Fernando Gomez (University of Caldas, Manizales, Colombia)
Geriatric assistance in South America
Assistenza geriatrica in Sud America
11.30 a.m.
Claudia Beghè (VA, Tampa, FL, USA)
Geriatric assistance in the USA
Assistenza geriatrica negli USA
12.00 a.m.
General Discussion
1.00 p.m Lunch - FREE afternoon
October 26 (Friday)
Morning
First Session
Nutritional Problems and Health -Mediterranean Diet and Physical Activity
Problemi Nutrizionali e Salute - Alimentazione Mediterranea e Attività Fisica
Chairmen
Carlo Cannella (University of Rome, Italy)
Mario Barbagallo (University of Palermo, Italy)
09.00 a.m.
Lorenzo M Donini (University of Rome, Italy)
Nutritional problems in the elderly
Problemi nutrizionali nell’anziano
9.30 a.m.
Carlo Cannella (University of Rome, Italy)
Diet and health in the elderly
Alimentazione e salute nell’anziano
10.00 a.m.
Marco Pahor (University of Florida, Gainesville, FL, USA)
Physical activity to preserve independence in older adults
Attività fisica e mantenimento della indipendenza nell’anziano
10.30 a.m.
Ligia J. Dominguez (University of Palermo, Italy)
Mediterranean diet and longevity: Role of extravirgin olive oil
Dieta mediterranea e longevità: Ruolo dell’olio extravergine di oliva
11.00 a.m. Coffee Break
Second Session
Diabetes and Cardiometabolic Syndrome in the Elderly
Diabete e Sindrome Metabolica nell’Anziano
Chairmen
Giuseppe Licata (University of Palermo, Italy)
Maurizio Averna (University of Palermo, Italy)
Ernesto Putignano (University of Palermo, Italy)
11.30 a.m.
Giuseppe Paolisso (Second University of Naples-SUN, Italy )
Diabetes in the elderly - Il diabete nell’anziano
12.00 a.m.
Nicola Ferrara (University of Molise, Italy)
Hypertension and antihypertensive therapy: Risk factors for diabetes?
Ipertensione e terapia antipertensiva: fattori di rischio di diabete?
12.30 p.m.
General Discussion
1.00 p.m to 3.00 p.m. Lunch
October 26 (Friday)
Afternoon
First Session
Chairmen
Alberto Notarbartolo (University of Palermo, Italy)
Ernesto Putignano (University of Palermo, Italy)
Carlo M. Barbagallo (University of Palermo, Italy)
03.30 p.m.
Patrizio Odetti (University of Genoa, Italy)
Metabolic syndrome and cognitive decline in the elderly
Sindrome metabolica e declino cognitivo nell’anziano
04.00 p.m.
Pierpaolo Ceda (University of Parma, Italy)
Hormonal dysregulation in the elderly: possible clinical impact
Disregolazione ormonale nell’anziano: possibile impatto clinico
04.30 p.m. Coffee Break
Second Session
Chairmen
Vincenzo Bellia (University of Palermo, Italy)
Giuseppe Costanza (University of Palermo, Italy)
04.45 p.m.
Raffaele Antonelli Incalzi (Campus Bio-Medico, University of Rome, Italy)
COPD in the elderly: a systemic disease
La BPCO nell’anziano: una malattia sistemica
05.15 p.m.
Antonio Cherubini (University of Perugia, Italy)
Depression in the elderly. The Dafne study
Depressione nell’anziano. Lo studio Dafne
05.45 pm
Domenico Cucinotta (Ospedale Villa Laura, Bologna )
Antiaging: charlatanry or science?
Antiinvechiamento: cialtroneria o scienza?
General Discussion
Adjourn
October 27 (Saturday)
Morning
First Session
Cardiovascular Diseases in the Elderly
Malattie Cardiovascolari nell’Anziano
Chairmen
Franco Rengo (University of Naples, Italy)
Salvatore Novo (University of Palermo, Italy)
09.00 a.m.
Roberto Sega (University of Milan, Italy)
Organ damage and cardiovascular risk in the metabolic syndrome. Data from the PAMELA study
Danno d’organo e rischio cardiovascolare nella sindrome metabolica. Dati dello Studio PAMELA
09.30 a.m.
Pasquale Abete (University of Naples, Italy)
Lifestyle and cardiovascular prevention in the elderly
Stile di vita e prevenzione cardiovascolare nell’anziano
10.00 a.m.
Franco Rengo (University of Naples, Italy)
Cardiac failure in the elderly
Lo scompenso cardiaco nell’anziano
10.30 a.m.
Niccolò Marchionni (University of Florence, Italy)
Acute coronary syndromes in the elderly. Conservative or invasive approach?
Sindromi coronariche acute nell’anziano. Approccio conservativo o interventistico?
11.00 a.m. - Coffee Break
Second Session
Dementia and Delirium in The Elderly
La Demenza e il Delirium nell’Anziano
Chairmen
Giuseppe Barbagallo (Nicosia, Italy)
Michelangelo Sapienza (Palermo, Italy)
11.30 a.m.
Marco Trabucchi (University of Rome/Brescia, Italy)
Delirium as a marker of the clinical condition in the elderly
Il delirium come marker della condizione clinica dell’anziano”
12.00 a.m.
Patrizia Mecocci (University of Perugia, Italy)
Clinical and therapeutic aspects of advanced stage Alzheimer’s disease
Aspetti clinici e terapeutici nella M. di Alzheimer in stato avanzato
12.30 p.m.
General Discussion
1.00p.m to 3.00 p.m. Lunch
October 27 (Saturday)
Afternoon
First Session
Chairmen
Sante Branca (Catania, Italy)
Michele Pagano (Palermo, Italy)
03.30 p.m.
Maurizio Bevilacqua (Osp. Sacco, Milan, Italy)
Hypernatremia and hyponatremia in the elderly
Ipernatriemia ed iponatriemia nell’anziano
04.00 p.m.
Francesco Corica (University of Messina, Italy)
Iatrogenic risk in the elderly patient
Il rischio iatrogeno nel paziente anziano
04.30 p.m. Coffee Break
Second Session
Chairmen
Giuseppe Rotolo (Palermo, Italy)
Luigi Spicola (Palermo, Italy)
04.45 p.m.
Mariano Malaguarnera (University of Catania, Italy)
Cancer pain in the elderly
Il Dolore da cancro nell’anziano
05.15p.m.
Giovanni Gambassi (University of Rome, Italy)
Pain management in the elderly
Cura del dolore nell’anziano
Third Session
Chairmen
Gioacchino Oddo (Palermo, Italy)
Vito Milazzo (Trapani, Italy)
05.45 p.m.
Luigi Galvano (Palermo, Italy)
The General Practioner and the Geriatrician: a sinergistic relationship?
Il MMG ed il Geriatra un rapporto sinergico? I nuovi LEA dell’assistenza domiciliare
06.10 p.m.
Umberto Alecci (Messina, Italy)
The General Practioner and the assistance to the frail elderly. Preliminary data from a regional
evaluation questionnaire in Sicily
Il MMG e l’assistenza all’anziano fragile. Dati preliminari sull’uso della scheda valutativa geriatrica della Regione Siciliana
General Discussion
Adjourn
October 28 (Sunday)
Morning
Osteoporosis and Disability in The Elderly
Osteoporosi e Disabilità nell’Anziano
First Session
Chairmen
Mario Passeri (University of Parma, Italy)
Giovam Battista Rini (University of Palermo, Italy)
09.00 a.m.
Stefania Maggi (Padua, Italy)
Epidemiology of osteoporosis
Epidemiologia dell’osteoporosi
09.30 a.m.
Domenico Maugeri (University of Catania, Italy)
Osteoporosis and disability in the elderly
Osteoporosi e disabilità nell’anziano
10.00 a.m.
Giancarlo Isaia (University of Turin, Italy)
Treatment of severe senile osteoporosis
La terapia dell’osteoporosi senile severa
10.30 a.m. Coffee Break
Second Session
Parkinson’s Disease In The Elderly
Malattia di Parkinson nell’Anziano
Chairmen
Mario Belvedere (University of Palermo, Italy)
Giovanni Savettieri (University of Palermo, Italy)
11.00 a.m.
Vittorio Nicita-Mauro (University of Messina, Italy)
Parkinson, parkinsonism and aging
Parkinson, parkinsonismo e invecchiamento.
11.30 a.m.
Letterio Morgante (University of Messina, Italy)
Treatment of advanced Parkinson’s disease in the elderly
Terapia della Malattia di Parkinson avanzata nell’anziano
12.00 a.m.
Mario Zappia (University of Catania, Italy)
Therapy of early stage Parkinson’s Disease
Terapia della Malattia di Parkinson in fase iniziale
12.30 p.m.
General Discussion
01.00 p.m.
Conclusion of the Course