2015
PhDAYS
SEPTEMBER 29-30
Biomolecular Sciences
Molecular and Cellular Biotechnology
CNR - NAPLES
Tuesday, September 29 – Aula Conferenze
10:00 - 12:30
Session 1 Structure and Function of Biomolecules
Faculty: R. Fattorusso, A. Fiorentino, C. Isernia, L. Vitagliano,
M. Ruvo, P. V. Pedone; G. Malgieri, A. Chambery,
B. D’Abrosca, A. Messere, R. Berisio,
Russomanno Anna 10:00 – 10:20
Peptide and protein labelling via Intein Chemistry
Tutor: D’ Andrea L.
Celentano Veronica 10:20 – 10:40
Chemical Tools for the conformational stabilization of
secondary structures in peptides
Tutors: D’Andrea L. C.
Balasco Nicole 10:40 – 11:00
Role of topology and of the intrinsic conformational
preferences of aminoacid residues in determining protein
three-dimensional structure
Tutors: Vitagliano L. and Isernia C.
Buonanno Martina 11:00 – 11:15
Insights into the structural and functional features of the tumor
associated protein hCA IX
Tutors: Monti S. M. and De Simone G.
Barone Daniela 11:15– 11:30
Structural characterization of the Hepatitis C Virus E2
glycoprotein: computational and experimental approaches.
Tutors: Vitagliano L. and Ruggero A.
D’ Abrosca Gianluca 11:30 – 11:50
The (unusual) aspartic acid in the metal coordination sphere
of the prokaryotic zinc finger domain
Tutor: Malgieri G.
Di Donato Cristina 11:50 – 12:00
Improvement of the physico-chemical properties of
guest molecules by supramolecular systems
Tutor: Iacovino R.
Rega Camilla 12:00- 12:10
Using mass spectrometry for protein structural and
functional studies: studying the Gadd45β/MKK7 complex,
a new target in Multiple Myeloma.
Tutor: Chambery A.
.
Graziani Vittoria 12:10 – 12:20
NMR characterization and antiproliferative activity of
secondary metabolites from fabaceae plants
Tutors: Fiorentino A. Potenza N.
Iaccarino Emanuela 12:20 – 12:30
Novel highly constrained peptide ligands for modulating the
activity of Cripto and activin-like receptors .
Tutors: Ruvo M. and Sandomenico A.
12:30 – 13:30 Lunch Break
13:30 – 16:30
Session 2 Human Genetics and Animal Models
Faculty: A. Usiello, V. Nigro, F. Gianfrancesco, S. Banfi, G. Piluso,
L. Rocco, F. Cerrato, V. Colonna
Vettone Antonella 13:30 – 13:50
DNA repair and resistance to DNA damage inducing drugs:
molecular mechanisms of DNA-alkyltransferases and
Fanconi Anemia pathway
Tutor: Ciaramella M.
Germoglio Marcello 13:50 – 14:05
Genetic interactions among repair genes
Tutor: La Volpe A.
Santonastaso Marianna 14:05 – 14:25
Protective role of antioxidants against genotoxicity
induced on human germ-cells by environmental pollutants:
myth or reality?
Tutor: Rocco L.
Padula Agnese 14:25 – 14:40
Finding new connections in the transcriptional regulation of
Lysine-specific demethylase 5C (KDM5C) a disease gene involved
in syndromic and non-syndromic XLID
Tutor: Miano M.G.
Di Fruscio Giuseppina 14:40 – 14:55
LysoPlex, a novel strategy to dissect the role of autophagy
in the muscle
Tutor: Nigro V.
Divisato Giuseppina 14:55 – 15:05
ZNF687 involvement in Giant Cell Tumor associated
with Paget’s disease of Bone
Tutor: Gianfrancesco F.
Nuzzo Tommaso 15:05 – 15:15
Rhes influences striatal cAMP/PKA-dependent signaling in a
gender-sensitive manner
Tutor: Usiello A.
Napolitano Filomena 15:15 – 15:30
A novel complex systemic disease: identification of the
responsible gene and characterization of its functional
role in vitro and in vivo
Tutor: Esposito T.
Sirica Roberto 15:30 – 15:40
Consequences of positive selection at lipid carrier ABCA12.
Tutor: Colonna V.
Santonicola Pamela 15:40 – 15:50
clt-2: a new C. elegans mutant and its interaction
with FA/BRC pathway
Tutor: La Volpe A.
Mazzarella Nadia 15:50 – 16:10
Identification of neuroprotective molecules using a
C. elegans model of Spinal Muscular Atrophy
Tutor: Di Schiavi E.
Valente Federica Maria 16:10 – 16:20
Two microduplications at the human centromeric 11p15
imprinting domain involving the CDKN1C gene are associated
with different growth phenotypes.
Tutor: Cerrato F.
Sorrentino Anna 16:20 – 16:30
Competing mRNA-miRNA network in Down syndrome
Tutor: Costa V.
Wednesday, September 30 – Aula Conferenze
14:00 – 16:20
Session 2 Gene Regulation and Microbiology
Faculty: A. Riccio, M. Sacco, N. Russo, A. Daniele; L. Muscariello
9:30 – 12:50
Session 1 Molecular Cell Biology
Chairman: G. Chieffi, A. Colanzi, V. Stingo, A. Lanni,
P. de Lange, L. Colucci
Fiorenzano Alessandro 9:30 – 9:50
Cripto is essential for generation and maintenance
of primed pluripotent stem cell state
Tutor: Minchiotti G.
Mancinelli Sara 9:50 – 10:00
Insights into neural stem cell biology from Cripto
Tutor: Liguori G.L.
Schiavone Valentina 10:00 – 10:20
SUMF1 controls self-renewal and differentiation of the
Hematopoietic Stem Cells
Tutors: Lania G. and Cosma M.P.
Schembri Laura 10:20 – 10:35
Study of the role of the Mono-ADP-Ribosyltransferase
PARP12 under physiological and stress conditions
Tutor: Corda D.
Amoruso Chiara 10:35 – 10:55
Molecular mechanism of the anti-invasive activity of
glycerophosphoinositols: role of the phosphatase Shp-1
Tutor: Corda D.
Filograna Angela 10:55 – 11:10
Investigating Lipid Droplets biogenesis: the role of CtBP1/BARS
Tutor: Corda D.
Sticco Lucia 11:10– 11:30
Role of Glucosylceramide in cell signalling
Tutor: D’Angelo G.
Subramanian Advait 11:30 – 11:50
Export of cargo from the Endoplasmic Reticulum is
regulated by a homeostatic control system
Tutor: Luini A.
Sonali Gopichand Chavan 11:50– 12:00
A bioinformatics approach to study novel functions
of the secretory pathway
Tutor: Luini A.
Varavallo Alessandra 12:00– 12:10
Control systems of the secretory pathway
Tutor: Luini A.
Prathyush Deepth Roy 12:10– 12:20
Functional organization of matrix proteins of the Golgi – their
contribution to the regulation of glycosylation
Tutor: Seetharaman Parashuraman.
Iannucci Liliana Felicia 12:20 – 12:30
Is autophagy a possible mechanism involved in the
effect of T2 on lipid mobilization?
Tutor: Lanni A.
Di Martino Rosaria 12:30 – 12:50
Proteomic approach reveals a new potential PKD
substrate involved in TGN to PM protein transport
Tutor: Luini A.
13:00 – 14:00 Lunch Break
Marino Maria Michela 14:00 – 14:15
Study of a CTCF mutant able to bind methylated DNA
Tutor: Pedone P.V.
Cammisa Marco 14:15 – 14:35
Closely located ( T,G)GCCGC motifs are recognized by
ZFP57 and lead to maintenance of repressive marks in
mouse embryonic stem cells
Tutor: Riccio A.
Kukrejia Harpreet 14:35 – 14:55
Role of ZFP57 in regulating epigenetic dynamics during
early embryogenesis
Tutor: Riccio A.
Shraddha Lad 14:55 – 15:15
Dynamics of the imprinting maintenance ZFP57/KAP1
and associated factors network at DNA methylated targets in
pluripotent ES cells and insights into a potential
developmental/differentiation role
Tutor: Grimaldi G.
Perrone Filomena 15:15 – 15:30
Stress response in Mycobacteria
Tutor: Muscariello L.
Della Corte Katia 15:30 – 15:50
Production of a human hormone of pharmaceutical interest
Tutor: Schiraldi C.
Mercurio Maria Emilia 15:50 – 16:10
Synthesis of modified oligonucleotides as post-trancriptional
regulators of gene expression
Tutor: Messere A.
Piccirillo Marina 16:10 – 16:20
Reconstruction of Genetic Network from Gene Perturbations
Tutor: Guarracino M.R
16:20 – 18:40
Session 3 Cancer Biology and Immunology
Faculty: M. Cipollaro, A. Baldi, M. Grieco, P. de Berardinis,
D. Boraschi, G. Del Pozzo
De Vincenzo Anna 16:20 – 16:40
Crosstalk between C-MYC and/or V12-RAS expressing
epithelial cells and normal fibroblasts
Tutor: Stoppelli M.P.
Belli Stefania 16:40 – 16:50
The 3D organotypic assay, a new methodology to study
tumor-stroma crosstalk
Tutor: Stoppelli M.P.
Durso Montano 16:50 – 17:10
The long non-coding RNA containing ultraconserved genomic
regions 8 promotes bladder cancer tumorigenesis
Tutor: Cimmino A.
Terreri Sara 17:10 – 17:20
Involvement of T-UCR 339+ in tumorigenesis
Tutor: Cimmino A.
Apicella Ivana 17:20 – 17:40
Generation and phenotypic analysis of PlGF-DE knock-in mouse
Tutor: De Falco S.
Cicatiello Valeria 17:40 – 18:00
Human IgG1 antibodies and IVIg suppress angiogenesis
independently of their target
Tutor: De Falco S.
Severino Renato 18:00 – 18:10
Innovative “Lab-on-Fiber” biosensors for cancer biomarker detection
Tutor: Ruvo M.
Mantile Francesca 18:10– 18:25
A consolidation phase in immune memory
Tutor: Prisco A.
Vitale Serena 18:25– 18:40
Ex-vivo analysis of cytokine production profile in intestinal mucosa
of children with inflammatory bowel diseas
Tutor: Gianfrani C.