A.R.C.A. Associazione Ricerche Cardiopatie Aritmiche Via A. Gabelli 86 35121 Padova http://anpat.unipd.it/ARCA Registro Regionale per la Patologia Cardio-Cerebro-Vascolare Azienda Ospedaliera di Padova Via A. Gabelli 61 35121 Padova Update in Arrhythmogenic Cardiomyopathy and Sudden Cardiac Death in the Young: novel technologies in cardiology, genetics, and pathology Aula Archivio Antico Palazzo del Bo via VIII Febbraio Padova-Italy March 20-21 2014 Università degli Studi di Padova Scientific Committee: Cristina Basso, Domenico Corrado, Gaetano Thiene UOC Patologia Cardiovascolare Dipartimento di Scienze Cardiologiche, Toraciche e Vascolari Università degli Studi di Padova Organizing Secretariat: Chiara Carturan Dipartimento di Scienze Cardiologiche, Toraciche e Vascolari Università degli Studi di Padova Via A. Gabelli 61 – 35121 Padova Admission is free. Send the completed registration form downloadable from the website http://anpat.unipd.it/ARCA/ to: [email protected] fax +39-049-827.2285 Under the auspices of: Thursday, March 20 14:00 14.10 14.15 Registration Authorities address › S. Iliceto (Padova, IT) Arrhythmogenic cardiomyopathy is a genetically determined disease › G.Thiene (Padova, IT) Advances in Clinical Diagnosis Chairmen: A. Anastasakis (Athens, Gr), L. Daliento (Padova, IT) 14.30-14.50 Updated clinical diagnostic criteria › F. I. Marcus (Tucson, USA) 14.50-15.10 ECG for early diagnosis › R. W. Hauer (Utrecht, NL) 15.10-15.30 Naxos Disease from the historical perspective › W.J. McKenna (London, UK) 15.30-15.50 Genetic screening: cost-benefit ratio › P. Charron (Paris, F) 15.50-16.20 Coffee Break New diagnostic tools, invasive and non-invasive Chairmen: L. Badano (Padova, IT), E. Bertaglia (Padova) 16.20-16.40 Cardiac magnetic resonance › M. Perazzolo Marra (Padova,IT) 16.40-17.00 Electro-anatomic mapping › F. Migliore (Padova, IT) 17.00-17.20 JUP immunolocalization as biomarker › A. Asimaki (Boston, USA) 17.20-17.40 Whole exome vs Targeted sequencing through NGS › L. Monserrat (La Coruna, E) 18:00 Guided Visit to "Il Bo" Old University Building › F. Zampieri & A. Zanatta (Padova, IT) Friday, March 21 Cluster Anatomia, Fisiologia e Patologia Cardiovascolare Development, Anatomy & Pathology ESC Working Group Myocardial and Pericardial Diseases ESC Working Group With the support of: Risk stratification, therapy and prevention of sudden death Chairmen: G. Buja (Padova, IT), R. Hauer (Utrecht, NL) 08.30-08.50 Drug Therapy › T. Wichter (Osnabrück, D) 08.50-09.10 Catheter ablation › H. Calkins (Baltimore, USA) 09.10-09.30 Risk stratification algorithm and ICD › D. Corrado (Padova, IT) 09.30-09.50 Implication on families for early carrier detection › A. A. Wilde (Amsterdam, NL) 09.50-10.20 Coffee Break Arrhythmogenic Cardiomyopathy and sudden death in athletes Chairmen: D. Corrado (Padova, IT), M. Schiavon (Padova, IT) 10.20-10.40 AC is still a cause of sudden cardiac death in athletes › C. Basso (Padova, IT) 10.40-11.00 RV Morpho-functional data in competitive athletes and the 2010 TF criteria › S. Caselli (Roma, IT) 11.00-11.20 Sport disqualification and lifestyle › B. Bauce (Padova, IT) 11.20-11.40 The role of semiautomatic defibrillator in case of cardiac arrest › N.A.M. Estes III (Boston, USA) 12.00-13.00 "From Bench To Bedside" free communications part I Chairmen: A. Caforio (Padova, IT), L. Leoni (Padova, IT) 1. 3d, strain, CT and nuclear/molecular modalities in AC › A. Abidov (Tucson, USA) 2. Sudden cardiac death in the combined US and Dutch AC datasets › J. Groeneweg (Utrecht, NL) 3. The impact of gender in desmosomal related AC › A. Protonotarios (Naxos, GR) 4. Role of exercise in AC › C. James (Baltimore, USA) 5. Cosegregation of MYBPC3 and DSP mutations in a family with AC › K. Pilichou (Padova, IT) 13:00-14:00 Lunch Break Advances in genetics and basic science Chairmen: F. Marcus (Tucson, USA), G. Thiene (Padova, IT) 14.00-14.20 Phospholamban › P. van Tintelen (Groningen, NL) 14.20-14.40 aT-catenin and area composita junctions › A. Rampazzo (Padova, IT) 14.40-15.00 Transgenic mice › A.J. Marian (Houston, USA) 15.00-15.20 Zebrafish › J.E. Saffitz (Boston, USA) 15.20-15.40 iPS cells › N. Elvassore (Padova, IT) 15.40-16.00 Cell Junction – Ion channel talks › M. Delmar (New York, USA) 16:00-16:20 Discussion 16.20-16.50 Coffee Break 16.50-18.00 "From Bench To Bedside" free communications part II Chairmen: C. Basso (Padova, IT), I. Rigato (Padova, IT) 1. Novel microscopy methods applied to the study of AC › A. Leo-Macias & E. Agullo-Pascual (New York, USA) 2. Plakoglobin as a regulator of the cardiac phenotype in AC › R. Lombardi (Houston, USA) 3. Towards improvement of early diagnosis and risk stratification in AC. › A.te Riele (Utrecht-Baltimore, NL/USA) 4. Phospholaban p Arg 14del mutation-related cardiomyopathy is a biventricular AC. › W.P. te Rijdt (Groningen, NL) 5. High-throughput reprograming for disease heterogeneity model › C. Luni (Padova, IT) 6. A homozygous founder mutation in desmocollin-2 causes AC in the Venetian population › A. Lorenzon (Padova, IT) 18:00 Closing of the Symposium