PrenatalSafe®: follow-up Febbraio 2014
No. of pregnancy with follow-up
No. of aneuploid samples
No.
Confirmed
4102
4100 (99.96%)
81 (2.0%)
79 (97.5%)
•
Trisomy 21
33
33 (100%)
•
Trisomy 18
9
9 (100%)
•
Trisomy 13
4
4 (100%)
•
Monosomy 18 (mosaic)
1
1 (100%)
•
Sex chromosomes
34
32/34 (94.1%)
 Monosomy X
18
16
 XXX
8
8
 XXY
5
5
 XYY
3
3
PrenatalSafe®: performance
No.
95% CI
No. of false positive
2
No. of false negative
0
No. of true positive
79
No. of true negative
4023
Sensitivity
100%
95.39 % - 100.00 %
Specificity
99.95%
99.82 % - 99.99 %
Positive Predictive Value
97.53%
91.35 % -99.63 %
Negative Predictive Value
100%
99.91 % -100.00 %