Cardiovascular Department,
“Ospedali Riuniti”and University of
Trieste,
Strada di Fiume 447,
34100 Trieste, Italy
Tel: +39-040-3994477
Fax: +39-040-3994153
e-mail:
[email protected]
Gianfranco SINAGRA was born in Palermo in 12th June
1964, married, 3 children.
Graduate in Medicine, Sumam cum Laude and Honors at the
University of Palermo on 21st of July 1987. Specialized in
Cardiology on the 6th of November 1992 at the University of
Trieste with 50/50 and honors grade.
Fellow of the European Society of Cardiology.
Assistant at the Cardiology Division – USL 1 TS;
University Hospital – since June 1991.
Since 11th January 1999 Chief of the Cardiology Division at
the University Hospital of Cattinara, Trieste.
Full Professor of Cardiology at the Trieste University since
30 December 2004.
Since 2009, Chief of Cardiovascular Department of
Cardiology and Surgery at Azienda OspedalieroUniversitaria, Ospedali Riuniti, Trieste.
Director of the Postgraduate School of Cardiology at
University of Trieste.
He participated as a Supervisor or Lecturer in more then 500
National and International Congresses and to Formation
Courses for hospital, extra-hospital and university
Cardiologists.
Member of the ESC-Working Group on Myocardial and
Pericardial disease and of the ESC Heart Failure
Association.
Component of the Group of Experts for the Superior
Council of the Italian Health Ministry (since 2007).
Associate Editor of the European Journal of Heart Failure.
Member of the Board of Auditors Heart-BMJ.
Associate Editor of the journal Nature, of the International
Scientific Advisory Board of the Journal of Cardiovascular
Medicine and Advisory Board of Macedonian Journal of
Medical Sciences.
Member of the Editorial Board of the journal CardioOncology.
Member of the Scientific Committee of the Italian Journal
of Cardiology
Member of the editorial board COCIS (Cardiology
Protocols for the Judgement of Fitness for Sports
Competitive).
Component Clinical Event Committee of the End Point Trial
ValHeFT
Research fellow at the Department of Cardiologic Sciences
of the St George’s Hospital of London (1989), and the
Wallenberg Laboratory for Cardiovascular Research of the
Sahlgrenska Hospital, Gothenburg University, Sweden
(1991 and 1993).
Several international Project in the setting of Heart Failure,
Cardiomyopathies and Genetics:
• Principal investigator since 2002 of the project
COMIRB: "Identification of a Gene for Autosomal
Dominant Dilated Cardiomyopathy on Chromosome
9", granted by the National Institute of HealthUSA,in cooperation with the Health Science Centre,
division of Cardiology, University of Colorado,
Denver.
• Component of the "main" research project under the
"FAMILIAL CARDIOMYOPATHY REGISTRY"
(NIH 99-177) that has generated: 1) project
RO1HL69071 NIH, GCRC RR00051-1575 and
UCHSC, SOM AEF; 2) Giant Gene Titin (TTN)
Involvement in Dilated Cardiomyopathy (project
NIH / NHLBI R95 - RS & G); 3) Analysis of
Altered SCN5A Ion Channel Function in the
Etiology of Dilated Cardiomyopathy (project
American Heart Association 0615547Z); 4) Genetic
Analysis of Intercalated Disks in ARVD / C (project
subjected to 'NIH / NHLBI).
• Member of the American Heart Association Project
SWA 12GRNT11770055 "Whole Exome
Sequencing to Discover Dilated Cardiomyopathy
Genes".
• Project Coordinator of Translational Research in
Cardiology (CTC).
• Coordinator, in 2004, of the Program of Finalized
Healthcare Research, Health Ministry, called
"Molecular mechanisms of negative and positive
post-infarctual ventricular remodelling".
• Head of the Centre of Trieste for the Ministerial
Project Research aimed "Italian Registry of family
dilated cardiomyopathy (RICAF): bases clinicalgenetics for optimizing therapy".
• Head, in 2008, of the Centre of Trieste for the
Ministerial Project Research aimed "Advanced Heart
Failure: new diagnostic and therapeutic
technologies".
• Head of the Centre of Trieste for the Ministerial
Project Research finalized: "Dilated
Cardiomyopathy and Gluten-dependent
autoimmunity".
• Head of the Centre of Trieste for the POR FESR
2007-2013; AXIS 1 "innovation, research,
technology transfer and entrepreneurship - support
for industrial research projects with high systemic
impact on the strengthening of networks of research
and innovation and of technological innovation
districts" - Projects industrial research about
molecular biomedicine.
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Head of Centre of Trieste for the E-Cardionet
Project, European Territorial Cooperation- program
for cross-border cooperation Italy-Slovenia.
Coordinator of the Project RF 2011;
Component of the project NIH 1 R01 HL11690601A1 “Genetics, Mechanisms and Clinical
Phenotypes of Arrhythmogenic Cardiomyopathy”;
Component of the project FRA: “New strategies for
improvements the prognosis of myocardial
infarction: role of metabolic-nutritional factors”;
Coordinator of the Project MIUR RF-201102348164
Ricerca
Finalizzata
Biomedicale
“CARDIOriGEN - MicroRNAs inducing cardiac
regeneration - From discovery towards clinical
application CARDIOriGEN - MicroRNAs inducing
cardiac regeneration”;
Collaboration in the setting of Heart Failure,
Cardiomyopathies and Genetics with:
• University of Colorado, Denver, Health Science
Center, Division of Cardiology; L. Mestroni, MD;
Ph D (Dilated Cardiomyopathy);
• Hammersmith Hospital, Neuromuscular Unit,
London; F. Muntoni, MD (Dilated
Cardiomyopathy);
• Dept of Cardiology, Baylor College of Medicine,
Houston and Dept of Medical and Molecular
Genetics;
• Indiana University School of Medicine, Indianapolis.
M. Vatta PhD (Dilated Cardiomyopathy);
• Dept of Cardiology, University of Cincinnati; Jeffrey
Towbin PhD (Genetically Determined
Cardiomyopathies);
• International Centre for Genetic Engineering and
Biotechnology, Trieste; M. Giacca, MD, PhD
(Molecular Cardiology);
• Institute of Pathology, University of Trieste; R.
Bussani, MD (Heart Failure, Cardiomyopathy and
Endomyocardial Biopsy);
• IRCCS Burlo Garofolo, Trieste, Department of
Molecular Medicine; G. Severini, PhD (Genetics of
Cardiomyopathies);
• Virginia Commonwealth University, Medicine
Department (A. Abate, MD, PhD), VCU Pauley
Heart Centre, Richmond, VA, USA;
• Mario Negri Pharmacological Research Institute,
Cardiovascular Research Department (R. Latini,
MD);
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University of Trieste, Engineering and Architecture
– Science and Technology of Materials Department,
O. Sbaizero;
Cardiovascular Center Aalst, Onze-LieveVrouwziekenhuis Clinic, Belgium; (E. Barbato, J.
Bartunek, W. Wijns);
The Heart Hospital London, UK (Prof. W.
McKenna);
Gonda Vascular Center Mayo Clinic, Rochester,
Minnesota; USA (Dr. Leslie T. Cooper);
Pathological Anatomy Department, University of
Udine (Dr A.P. Beltrami);
University of Rome "La Sapienza", (Dr. M. Testa);
Clinical Physiology Institute of CNR and of the
Sant’Anna School of Pisa (Dr F. Recchia);
He’s the author of more than 460 publications under
Structured Work form, published in Books and National and
International Scientific Magazines.
(H-index 38; total IF > 700)
http://thomsonreuters.com/thomson-reuters-web-of-science/
(2/2015)