Downloaded from http://annonc.oxfordjournals.org/ by guest on May 6, 2015 Downloaded from http://annonc.oxfordjournals.org/ by guest on May 6, 2015 Downloaded from http://annonc.oxfordjournals.org/ by guest on May 6, 2015 Random assignment n = 147 ARM A: n = 49 ARM B: n = 48 Not treated: n = 1 Patient required therapy procedure not permitted Tr eated: n = 48 ARM C: n = 50 Not treated: n = 1 1 patient had presence of CNS m+ Tr eated: n = 48 Tr eated: n =49 Downloaded from http://annonc.oxfordjournals.org/ by guest on May 6, 2015 Downloaded from http://annonc.oxfordjournals.org/ by guest on May 6, 2015 Downloaded from http://annonc.oxfordjournals.org/ by guest on May 6, 2015 16. 17. 18. 19. 20. 21. 22. 23. 24. 25. 26. 27. 28. 29. 30. 31. Downloaded from http://annonc.oxfordjournals.org/ by guest on May 6, 2015 1. Crinò L, Scagliotti GV, Ricci Set al. 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