Curriculum Vitae PERSONAL INFORMATION Michele Mancinelli Michele Mancinelli Via Fortunato Savini, n° 7, 62032, Camerino (MC), Italia 3381196573 [email protected]; http://ms.fci.unibo.it/~mazzand/michele.html [email protected]; Sex M | Date of birth 04/07/1981 | Nationality Italy WORK EXPERIENCE 01/05/2014 – today Supervisor University and Faculty Post Ph.D. Prof. Andrea Mazzanti University of Bologna – Viale del Risorgimento 4 – Department of Industrial Chemistry “Toso Montanari” http://ms.fci.unibo.it/~mazzand Design and synthesis of new atropisomeric chiral molecules and determination of their absolute configuration; these molecules are studied by means of: 1) Nuclear Magnetic Resonance at variable temperature; 2) mono (DEPT, NOE) and bidimensional (COSY, HSQC, HMBC, NOESY, DPFGSENOE) NMR; 3) kinetic NMR experiments (EXSY e 1-D saturation transfer); 4) Electronic and Vibrational Circular Dichroism; 5) X-ray diffractometry; 6) Conformational studies with computational DFT and TDDFT calculations. 01/05/2013 – 30/04/2014 Supervisor University and Faculty Post Ph.D. Prof. Andrea Mazzanti University of Bologna – Viale del Risorgimento 4 – Department of Industrial Chemistry “Toso Montanari” Synthesis and Conformational studies of Atropisomeric organic molecules. 04/03/2013 – 23/06/2013 Post Ph.D. abroad in Biotools, Florida President Rina K. Dukor, Jupiter, Florida, America Company: BioTools Work and Study based on Vibrational Circular Dichroism Letter Biotools attached 1 01/05/2009 – 30/04/2013 Post Ph.D. Prof. Andrea Mazzanti University of Bologna – Viale del Risorgimento 4 – Department of Organic Chemistry “A. Mangini” Synthesis and Conformational studies of Atropisomeric organic molecules Pagina 1 / 6 Curriculum Vitae Michele Mancinelli EDUCATION AND TRAINING 01/01/2006-31/12/2008 Ph.D. University of Bologna, Organic Chemistry “A. Mangini”, Chemical Sciences XXI cycle, chim/06 Course Title of Thesis Supervisor Assistant Supervisor 03/03/2008-18/07/2008 ▪ Dynamic NMR ▪ Conformational and Stereodinamic of Hindered Aromatic Systems ▪ Prof. Lodovico Lunazzi ▪ Dr. Andrea Mazzanti Ph.D. abroad in Manchester University of Manchester, faculty of Organic Chemistry Title Thesis Supervisor ▪ Carbamate’s rearrangement ▪ Prof. Jonathan Clayden Attendance Postgraduate School: 12/09/2010-16/09/2010 XXXIII National Symposium of Organic Chemistry of SCI (CODiCO 2010), San Benedetto del Tronto (AP). Proceeding and Flash Presentation entitled: Dual axis of Chirality in anthrones and anthraquinones bis-substituted 20/10/2008-22/10/2008 VIII Sigma-Aldrich Young Chemists Symposium (SAYCS), Pesaro. Proceeding entitled: Steric and π Barrier in aryl system: the case of bi-phenylens. 11/01/2007-18/01/2007 Winter School Physical Organic Chemistry WISPOC 2006, Bressanone 19/06/2006-23/06/2006 XXXI Summer Course ‘A.Corbella’, Seminar of Organic chemistry, Gargnano of Garda 2003-2005 Achieved Vote University Faculty Course Denomination Course Title of Thesis Type of Thesis Supervisor 01/03/2005-31/06/2005 Country University Faculty Title of thesis Supervisor Degree 26/10/2005 110 (su 110) cum laude ▪ Studies University of Camerino ▪ Science and Technology ▪ Chemistry and Avanced Methodology Chemistry (Class 26/S) ▪ Synthesis and Molecular Reactivity ▪ “Nuove Metodologie a Basso Impatto Ambientale nella Formazione di Legami Carbonio-Carbonio Promossa dal Sistema CeCl3 7H2O/NaI” ▪ Experimental thesis, 12 months lengh with a 4 months of experience abroad ▪ Prof. Enrico Marcantoni Thesis experience abroad ▪ Spain ▪ University of Sevilla ▪ Organic Chemistry ▪ “Allilazione Poliidrossifurano Promossa dal Sistema CeCl3 7H2O/NaI” ▪ Prof. José G. Fernández-Bolaños Pagina 2 / 6 Curriculum Vitae 2000-2003 Achivied Vote University Faculty Course denomination Supervisor 1995-2000 Achivied Vote Type School Course 11/09/200-01/10/2000 Country Michele Mancinelli Bachelor Degree 22/10/2003 110 (su 110) cum laude ▪ Studies University of Camerino ▪ Science and Technology ▪ Chemistry (Class 21) ▪ Prof. Enrico Marcantoni Secondary School / High School 2000 95/100 ▪ ITIS - Istitute Technical Industrial State ▪ Chemistry Europian Union Program Project Leonardo ▪ Germania PERSONAL SKILLS Mother tongue Other languages English Italian UNDERSTANDING SPEAKING WRITING Listening Reading Spoken Interection Spoken production Good Good Good Good Good Medium Medium Intermediate Level Spanish Medium Medium Medium Base Level Communication skills Ability to interact in a Laboratory of Organic Chemistry. Ability to present the work done in postgraduate schools. Organisational/ managerial skills PostDoc in a laboratory of Organic Chemistry and NMR spectroscopy. I follow projects of thesis and Ph.D. thesis. I use equipment such as Nuclear Magnetic Resonance (300, 400 e 600 MHz), ECD e VCD instrument, analitical and semipreparative HPLC and GS-MS. Job-related skills Good skills in Organic Synthesis, NMR spectroscopy, electronic and vibrational circular dichroism. Knowledge of techniques of separation of organic compounds, such as chromatography, distillation and crystallization. Good skills in computational calculation of organic molecules with the program Gaussian09. Good skills in the determination of absolute configuration in chiral molecules. Pagina 3 / 6 Curriculum Vitae Computer skills Sport and Hobbie Driving licence Michele Mancinelli ▪ Good knowledge of Microsoft Office tools, such as word, excel, powerpoint ▪ Good knowledge of the research chemistry program SciFinder ▪ Good knowledge of ChemBioOffice tools, in particular ChemDraw ▪ Knowledge of programs such as PhotoPaint, and Macromedia Flash 8 ▪ Good knowledge of Gaussian 09 ▪ Knowledge of programming in vba, xhtml ▪ Knowledge of the linux operating system Soccer, running, and logic games. A2 ; B ADDITIONAL INFORMATION Publications 1) N. Di Iorio, P. Righi, A. Mazzanti, MICHELE MANCINELLI, A. Ciogli, G. Bencivenni (2014). Remote Control of Axial Chirality: Aminocatalytic Desymmetrization of N-Arylmaleimides via Vinylogous Michael Addition. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol 136; p. 10250-10253, doi: 10.1021/ja505610k 2) M. Chiarucci, A. Ciogli, MICHELE MANCINELLI, S. Ranieri, A. Mazzanti (2014). The Experimental Obserbvation of the Intramolecular NO2/CO Interaction in Solution. ANGEWANDTE CHEMIE INTERNATIONAL EDITION, vol. 53; p. 5405-5409, doi: 10.1002/anie.201402366 3) M. C. Cassani, M. A. Brucka, C. Femoni, MICHELE MANCINELLI, A. Mazzanti, R. Mazzoni, G. Solinas (2014). N-Heterocyclic carbene rhodium(i) complexes containing an axis of chirality: dynamics and catalysis. NEW JOURNAL OF CHEMISTRY, vol. 38; p. 1768-1779, ISSN: 1144-0546, doi: 10.1039/c3nj01620j 4) M. Ambrogi, A. Ciogli, MICHELE MANCINELLI, S. Ranieri, A. Mazzanti (2013). Atropisomers of arylmaleimides: Stereodynamics and absolute configuration. JOURNAL OF ORGANIC CHEMISTRY, vol. 78; p. 3709-3719, ISSN: 0022-3263, doi: 10.1021/jo400200v 5) L. Lunazzi, MICHELE MANCINELLI, A. Mazzanti (2012). Atropisomers of Hindered Triarylisocyanurates: Structure, Conformation, Stereodynamics, and Absolute Configuration. JOURNAL OF ORGANIC CHEMISTRY, vol. 77; p. 3373-3380, ISSN: 0022-3263, doi: 10.1021/jo300192n 6) J. L. Xia, S. H. Liu, F. Cozzi, MICHELE MANCINELLI, A. Mazzanti. (2012). An Experimental Study of the Effect of Substituents on the Aromatic-Aromatic Interactions in Some Dithia-[3,3]-metaparacyclophanes. CHEMISTRY-A EUROPEAN JOURNAL, vol. 18; p. 3611-3620, ISSN: 0947-6539, doi: 10.1002/chem.201103639 Pagina 4 / 6 Curriculum Vitae Publications Michele Mancinelli 7) L. Lunazzi, MICHELE MANCINELLI, A. Mazzanti, S. Lepri, R. Ruzziconi, M. Schlosser (2012). Rotational Barriers of Biphenyls Having Heavy Heteroatoms as ortho-Substituents: Experimental and Theoretical Determination of Steric Effects. ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 10; p. 1847-1855, ISSN: 14770520, doi: 10.1039/c1ob06688a 8) G. Cera, M. Chiarucci, A. Mazzanti, MICHELE MANCINELLI, M. Bandini (2012). Enantioselective Gold-Catalyzed Synthesis of Polycyclic Indolines. ORGANIC LETTERS, vol. 14; p. 1350-1353, ISSN: 1523-7060, doi: 10.1021/ol300297t 9) L. Lunazzi, MICHELE MANCINELLI, A. Mazzanti (2011). Structure, Conformation, Stereodynamics and Absolute Configuration of the Atropisomers of Fluorenylidene Derivatives. JOURNAL OF ORGANIC CHEMISTRY, vol. 76; p. 1487-1489, ISSN: 0022-3263, doi: 10.1021/jo1023427 10) F. Pesciaioli, P. Righi, A. Mazzanti, C. Gianelli, MICHELE MANCINELLI, G. Bartoli, G. Bencivenni (2011). Cinchona Alkaloid-Catalyzed Enantioselective Direct Aldol Reaction of N-Boc-Oxindoles with Polymeric Ethyl Glyoxylate. ADVANCED SYNTHESIS & CATALYSIS, vol. 353; p. 2953-2959, ISSN: 1615-4150, doi: 10.1002/adsc.201100499 11) D. Casarini, MICHELE MANCINELLI, A. Mazzanti, F. Boschi (2011). Stereodynamics and absolute configuration of stereolabile atropisomers in 2,2-dimethyl-1-aryl-1indanols. CHIRALITY, vol. 23; p. 768-778, ISSN: 0899-0042, doi: 10.1002/chir.20988 12) L. Busetto, M. C. Cassani, C. Femoni, MICHELE MANCINELLI, A. Mazzanti, R. Mazzoni, G. Solinas (2011). N-Heterocyclic Carbene-Amide Rhodium(I) Complexes: Structures, Dynamics, and Catalysis. ORGANOMETALLICS, vol. 30; p. 5258-5272, ISSN: 0276-7333, doi: 10.1021/om200631w 13) L. Lunazzi, MICHELE MANCINELLI, A. Mazzanti, M. Pierini (2010). Stereomutation of Axially Chiral Aryl Coumarins. JOURNAL OF ORGANIC CHEMISTRY, vol. 75; p. 5927-5933, ISSN: 0022-3263, doi: 10.1021/jo101261k 14) M. Benaglia, F. Cozzi, MICHELE MANCINELLI, A. Mazzanti (2010). The Intramolecular Interaction of Thiophene and Furan with Aromatic and Fluoroaromatic Systems in Some [3.3]Meta(heterocyclo)paracyclophanes: A Combined Computational and NMR Spectroscopic Study. CHEMISTRY-A EUROPEAN JOURNAL, vol. 16(25); p. 7456-7468, ISSN: 0947-6539, doi: 10.1002/chem.201000783 15) L. Lunazzi, MICHELE MANCINELLI, A. Mazzanti (2010). Structure and Stereodynamics of Aryldiimino Derivatives. JOURNAL OF ORGANIC CHEMISTRY, vol. 75; p. 2572-2577, ISSN: 0022-3263, doi: 10.1021/jo100106t 16) D. Casarini, L. Lunazzi, MICHELE MANCINELLI, A. Mazzanti, P. Scafato (2009). Conformation and Absolute Configuration of 2-Naphthylalkylsulfoxides by Combined Use of Dynamic NMR, ECD Spectroscopy, DFT Computations and X-Ray Diffraction. CHIRALITY, vol. 21; p. 16-23, ISSN: 0899-0042, doi: 10.1002/chir.20587 17) L.-Y. Wu, G. Bencivenni, MICHELE MANCINELLI, A. Mazzanti, G. Bartoli, P. Melchiorre (2009). Organocascade Reactions of Enones Catalyzed by a Chiral Primary Amine. ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, vol. 48; p. 7196-7199, ISSN: 1433-7851, doi: 10.1002/anie.200903280 18) L. Lunazzi, MICHELE MANCINELLI, A. Mazzanti (2009). Structure, Stereodynamics and Absolute Configuration of the Atropisomers of Hindered Arylanthraquinones. JOURNAL OF ORGANIC CHEMISTRY, vol. 74; p. 1345-1348, ISSN: 0022-3263, doi: 10.1021/jo802383s 19) J. Clayden, W. Farnaby, D.M. Grainger, U. Hennecke, MICHELE MANCINELLI, D.J. Tetlow, I.H. Hillier, M.A. Vincent (2009). N to C Aryl Migration in Lithiate Carbamates: a-Arylation of Benzylic Alcohols. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 131; p. 3410-3411, ISSN: 0002-7863, doi: 10.1021/ja808959 Pagina 5 / 6 Curriculum Vitae Publications Michele Mancinelli 20) L. Lunazzi, MICHELE MANCINELLI, A. Mazzanti (2008). Arylbiphenylenes Atropisomers: Structure, Conformation, Stereodynamics and Absolute Configuration. JOURNAL OF ORGANIC CHEMISTRY, vol. 73; p. 2198 - 2205, ISSN: 0022-3263 21) L. Lunazzi, MICHELE MANCINELLI, A. Mazzanti (2008). Stereodynamics and Conformational Chirality of the Atropisomers of Ditolyl Anthrones and Anthraquinone. JOURNAL OF ORGANIC CHEMISTRY, vol. 73; p. 5354-5359, ISSN: 0022-3263, doi: 10.1021/jo800677n 22) G. Bartoli, J.G. Fernandez-Bolanos, G. Di Antonio, G. Foglia, S. Giuli, R. Gunnella, MICHELE MANCINELLI, E. Marcantoni, M. Paoletti. (2007). SiO2-Supported CeCl3.7H2O-NaI Lewis Acid Promoter: Investigation into the Garcia Gonzalez Reaction in Solvent-Free Conditions. JOURNAL OF ORGANIC CHEMISTRY, vol. 72; p. 6029-6036, ISSN: 0022-3263, doi: 10.1021/jo070384c 23) D. Casarini, L. Lunazzi, MICHELE MANCINELLI, A. Mazzanti (2007). Conformation and Stereodynamics of Symmetrically Ortho-Disubstituted Aryl Carbinols and Aryl Ethers. JOURNAL OF ORGANIC CHEMISTRY, vol. 72; p. 998-1004, ISSN: 00223263, doi: 10.1021/jo062289u 24) D. Casarini, L. Lunazzi, MICHELE MANCINELLI, A. Mazzanti, C. Rosini (2007). Structure, Conformation, Stereodynamics, Dimer Formation and Absolute Configuration of Axially Chiral Atropisomers of Hindered Biphenyl Carbinols. JOURNAL OF ORGANIC CHEMISTRY, vol. 72; p. 7667-7676, ISSN: 0022-3263, doi: 10.1021/jo701481m 25) L. Lunazzi, MICHELE MANCINELLI, A.Mazzanti (2007). Correct Values of the Rotation Barriers of 1,8-Ditolylanthracenes. JOURNAL OF ORGANIC CHEMISTRY, vol. 72; p. 5391-5394, ISSN: 0022-3263, doi: 10.1021/jo070679q 26) L. LUNAZZI, MICHELE MANCINELLI, A. MAZZANTI (2007). Unprecedented Detection of the Enantiomerisation pi-Barriers due to Restricted Aryl Torsion: the Case of 1,8-Di-arylbiphenylenes. JOURNAL OF ORGANIC CHEMISTRY, vol. 72; p. 10045 - 10050, ISSN: 0022-3263 Attached 1) 2) Letter of BioTools Identity Card Pagina 6 / 6