Europass
Curriculum Vitae
Personal information
First name(s) / Surname(s)
Address(es)
Giovanna Romeo
Department of Medical-Surgical Sciences and Biotechnologies,
Corso della Repubblica, 79 04100 Latina - Italy
Telephone(s)
3907731757210
Fax(es)
3907731757219
E-mail
Nationality
Date of birth
Gender
Mobile:
+393398259862
[email protected]
italian
25/03/ 1954
female
Occupational field (S s/d)
Associate professor MED/04 General Pathology
Work experience
From 4/6/2010 up to date
from 1/1/2005 to 3/6/2010
from September 1990 to February2003
from February 2003 to december 2004
2011-2012
Teaching activities
Name and address of employer
Sector
Present position: Associate Professor MED-04 General Pathology – Department of Medical-Surgical
Sciences and Biotechnologies, School of Pharmacy and Medicine, Sapienza University of Rome;
Associate Professor MED-04 General Pathology - Department of Experimental Medicine - School of
Medicine and Surgery, Sapienza University of Rome, Italy
Technologist of Consiglio Nazionale delle Ricerche, Institute of Biomedical Technologies, Rome
Technologist of Consiglio Nazionale delle Ricerche , Institute of Molecular Biology and Pathology,
Rome
Scientific Coordinator of PhD in Innovative Technologies in Traslational Medicine
- Biochemistry, School of Biotechnology of University “La Sapienza” Rome, from 1997/1998 to
2004/2005
- Immunology, School of Medicine (now School of Pharmacy and Medicine)-, Sapienza University of
Rome - 2002-03 to date
- General Pathology, School of Nurse, Technics of Biomedical Laboratory, Dental Hygiene - 2002-03
to date
Department of Medical-Surgical Sciences and Biotechnologies, School of Pharmacy and Medicine,
Sapienza University of Rome, Corso della Repubblica, 79 - 04100 Latina
University, School of Medicine
Education and training
1973-1978
Page 1/4 - Curriculum vitae of
Surname(s) First name(s)
Degree in Chemistry ( 110/110)
School of Chemistry, University of Naples, Italy
For more information on Europass go to http://europass.cedefop.europa.eu
© European Union, 2004-2010 24082010
1975-1978
1981-1982
1982-1990
Internal Student, Institute of Biochemistry, School of Medicine and Surgery, University of Naples, Italy
Field of Study:Protein Biochemistry-Enzymology
-Fellowship Istituto Superiore di Sanità, Rome, Laboratory of Virology
Field of Study:Biochemistry of Interferon system
-Fellowship Consiglio Nazionale delle Ricerche, Rome
Field of Study:Signal transduction in Interferon antiviral and antigrowth activities
Personal skills and studies on signal transduction pathways in antitumor effects of type I Interferon (IFN) in Human
competences Papilloma Virus (HPV)-transformed cells. IFN-induced genes, cell cycle progression, apoptosis and
senescence studies.
Mother tongue(s)
Other language(s)
Italian
English, french
Self-assessment
Understanding
Listening
European level (*)
Reading
Speaking
Spoken interaction
Writing
Spoken production
English
B2 Independent user B2 Independent user B2 Independent user B2 Independent user C1
French
A2
Basic user
Basic user
A2
Basic user
(*) Common European Framework of Reference for Languages
Additional information
Annexes Publications
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Surname(s) First name(s)
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© European Union, 2004-2010 24082010
A2
Basic user
A2
Proficient user
Basic user
Peer reviewed publications of Giovanna Romeo (selected in the last 15 years from total 80)
Impact
factor
(2010)
1
2
3
MANGINO G, PERCARIO ZA, FIORUCCI G, VACCARI G, ACCONCIA F, CHIARABELLI C, LEONE S, NOTO A,
HORENKAMP FA, MANRIQUE S, ROMEO G, POLTICELLI F, GEYER M, AFFABRIS E. (2011). HIV-1 Nef Induces
Proinflammatory State in Macrophages through Its Acidic Cluster Domain:Involvement of TNF Alpha Receptor
Associated Factor 2.
PLoS ONE. 6(8): e22982
CHIANTORE MV, VANNUCCHI S, MANGINO G, PERCARIO ZA, AFFABRIS E, FIORUCCI G, ROMEO G. (2009).
Senescence and Cell Death Pathways and
Their Role in Cancer Therapeutic Outcome.
CURRENT MEDICINAL CHEMISTRY, vol. 16; p. 287-300
MANGINO G, PERCARIO ZA, FIORUCCI G, VACCARI G, MANRIQUE S, ROMEO G., FEDERICO M, GEYER M,
AFFABRIS E (2007). In vitro treatment of human monocytes/macrophages with myristoylated recombinant Nef of
human immunodeficiency virus type 1 leads to the activation of mitogen-activated protein kinases, I kappa B
kinases, and interferon regulatory factor 3 and to the release of beta interferon.
JOURNAL OF VIROLOGY, vol. 81; p. 2777-2791
4.4
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VANNUCCHI S, CHIANTORE M.V, MANGINO G, PERCARIO Z.A, FIORUCCI G, AFFABRIS E, ROMEO G. (2007).
Perspectives in biomolecular therapeutic intervention in cancer: from the early to the new strategies with type I
nterferons. CURRENT MEDICINAL CHEMISTRY, vol. 14; p. 667-679
5
FIORUCCI G, VANNUCCHI S, CHIANTORE MV, PEREARIO ZA, AFFABRIS E, ROMEO G. (2005). TNF-related
apoptosis-inducing ligand (TRAIL) as a pro-apoptotic signal transducer with cancer therapeutic potential.
CURRENT PHARMACEUTICAL DESIGN, vol. 11; p. 933-944,
4.8
6
VANNUCCHI S., CHIANTORE M.V., FIORUCCI G., PERCARIO Z.A., LEONE S., AFFABRIS E., ROMEO G.
(2005). TRAIL is a key target in S-phase slowing-dependent apoptosis induced by interferon-beta in cervical
carcinoma cells. ONCOGENE, vol. 24; p. 2536-2546
7.4
OLIVETTA E, PERCARIO Z, FIORUCCI G, MATTIA G, SCHIAVONI A, DENNIS C, JAGER J, HARRIS M, ROMEO
G., AFFABRIS E, FEDERICO M (2003). HIV-1 Nef induces the release of inflammatory factors from human
monocyte/macrophages: Involvement of nef endocytotic signals and NF-kappa B activation.
JOURNAL OF IMMUNOLOGY, vol. 170; p. 1716-1727
5.7
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PERCARIO Z, OLIVETTA E, FIORUCCI G, MANGINO G, PERETTI S, ROMEO G., AFFABRIS E, FEDERICO M.
(2003). Human immunodeficiency virus type 1 (HIV-1) Nef activates STAT3 in primary human
monocyte/macrophages through the release of soluble factors: involvement of Nef domains interacting with the cell
endocytotic machinery.
JOURNAL OF LEUKOCYTE BIOLOGY, vol. 74; p. 821-832
ROMEO G., FIORUCCI G, CHIANTORE M.V, PERCARIO Z.A, VANNUCCHI S, AFFABRIS E (2002). IRF-1 as a
Negative regulator of cell proliferation.
JOURNAL OF INTERFERON AND CYTOKINE RESEARCH, vol. 22; p. 39-47
FEDERICO M., PERCARIO Z., OLIVETTA E., FIORUCCI G., MURATORI C., MICHELI A., ROMEO G., AFFABRIS
E. (2001). Human immunodeficiency virus type 1 Nef activates STAT1 in human monocytes/macrophages through
the release of soluble factors.
BLOOD, vol. 98; p. 2752-2761
VANNUCCHI S, PERCARIO Z.A, MATARRESE P, CHELBI-ALIX M.K, FAGIOLI M, PELICCI P.G, MALORNI W,
FIORUCCI G, ROMEO G., AFFABRIS E (2000). Interferon-beta induces S-phase slowing via up-regulated
expression of PML in squamous carcinoma cells.
ONCOGENE, vol. 19; p. 5041-5053
PERCARIO Z.A, GIANDOMENICO V, FIORUCCI G, CHIANTORE M.V, VANNUCCHI S, HISCOTT J, AFFABRIS E,
ROMEO G. (1999). Retinoic acid is able to induce IRF-1 in squamous carcinoma cells via a STAT-1 independent
signalling pahway.
CELL GROWTH & DIFFERENTIATION, vol. 10; p. 263-270
GIANDOMENICO V., VACCARI G., FIORUCCI G., PERCARIO Z., MATARRESE P., MALORNI W., ROMEO G.,
AFFABRIS E. (1998). Apoptosis and growth inhibition of squamous carcinoma cells treated with IFN-alpha, IFN-beta
and retinoic acid are associated with induction of the cyclin-dependent kinase inhibitor P21.
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Surname(s) First name(s) © European Union, 2004-2010 24082010
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EUROPEAN CYTOKINE NETWORK, vol. 9; p. 613-631
17
MATARRESE P., GIANDOMENICO V., FIORUCCI G., RIVABENE R., STRAFACE E., ROMEO G., AFFABRIS E.,
MALORNI W. (1998). Antiproliferative activity of interferon * and retinoic acid in SiHa carcinoma cells: the role of cell
adhesion.
INTERNATIONAL JOURNAL OF CANCER, vol. 76; p. 531-540
GIANDOMENICO V., LANCILLOTTI F., FIORUCCI G., PERCARIO Z.A., RIVABENE R., MALORNI W., AFFABRIS
E., ROMEO G. (1997). Retinoic acid and interferon inhibition of cell proliferation is associated with apoptosis in
squamous carcinoma cell lines. Role of IRF-1 and TGAseII-dependent pathways.
CELL GROWTH & DIFFERENTIATION, vol. 8; p. 91-100
FIORUCCI G, PERCARIO Z.A, MARCOLIN C, COCCIA E.M, AFFABRIS E, ROMEO G. (1995). Inhibition of protein
phosphorylation blocks interferon-induced gene expression and modulates expression of the JAK family protein
tyrosine kinases.
JOURNAL OF VIROLOGY, vol. 69; p. 5833-5837
LANCILLOTTI F, GIANDOMENICO V, AFFABRIS E, FIORUCCI G, ROMEO G., ROSSI G.B (1995). IFN-alpha2b
and retinoic acid combined treatment affects proliferation and gene expression of human cervical carcinoma cells.
CANCER RESEARCH, vol. 55; p. 3158-3164
18
PERCARIO Z.A., FIORUCCI G., MARCOLIN C., MANGINO G., AFFABRIS E., ROMEO G. (1995). Staurosporine
inhibits interferon *-induced gene expression in Friend erythroleukemia cells through a PKC independent pathway.
JOURNAL OF BIOLOGICAL REGULATORS & HOMEOSTATIC AGENTS, vol. 9; p. 7-14
14
15
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Surname(s) First name(s)
For more information on Europass go to http://europass.cedefop.europa.eu
© European Union, 2004-2010 24082010
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