Breast cancer
epidemiology
Dr Andrea Micheli
Director
Descriptive Studies and Health Planning Unit
Fondazione IRCCS "Istituto Nazionale dei Tumori"
Milano
BREAST CANCER INCIDENCE
BREAST CANCER MORTALITY
COLORECTAL CANCER INCIDENCE
COLORECTAL CANCER INCIDENCE
GROSS DOMESTIC PRODUCT AND
CANCER INCIDENCE
World standardised incidence rates per 100,000, GDP: ppp US $, 2006.
Fonte: GLOBOCAN 2002, IARC & United Nations (UN)
GROSS DOMESTIC PRODUCT AND
CANCER MORTALITY
World standardised mortality rates per 100,000, GDP: ppp US $, 2006.
Fonte: GLOBOCAN 2002, IARC & United Nations (UN)
BREAST CANCER
Incidence per 100,000 - Std Eu
J. Ferlay et al. EJC 2010
Age-standardised relative survival
CONCORD
c. Tumore della mammella - Femmine - Tutte le razze
100%
80%
Sopravvivenza relativa (%)
USA (Seer)
USA (Concord)
Canada
60%
Giappone
Australia
Europa Nord
40%
Europa Sud-Ovest
UK+Irlanda
Europa Est
20%
0%
0
1
2
3
4
5
Anni dalla diagnosi
Standard: ICSS
Sopravvivenza relativa a 5 anni
dalla diagnosi l (%)
Age-standardised relative survival
Europe vs USA
100
90
81
85
86
88
77
76
74
89
80
70
60
74
67
50
40
30
SEER
EUROCARE
20
10
0
15-44
45-54
55-64
Età alla diagnosi
65-74
75-99
Fonte: EUROCARE
LIFE
EXPECTANCY
TRENDS IN
EUROPE
Fonte: United Nations
Population Division
GDP and standardised incidence rate for all tumours. Women
Fonte: Human Development Report 2009; Ferlay et al. 2008
GDP and standardised mortality rate for all tumours. Women
Disks are proportional to the public health expenditure ($ PPP)
Fonte: Human Development Report 2009; Ferlay et al. 2008
BREAST CANCER
incidence and mortality
Italy, 1970-2010, 0-84 yrs
Std EU, rate per 100,000
Grande E. et al. Regional estimates of breast cancer burden in Italy. Tumori 2007
BREAST CANCER
Mortality per 100,000 - Std Eu
J. Ferlay et al. EJC 2010
BREAST CANCER MORTALITY IN EUROPE
rates per 100,000 - Std Eu
WHO Mortality database
5YR BREAST CANCER RELATIVE SURVIVAL AND
DEATH RISK IN EUROPE
Fonte: Verdecchia A. et al. EJC 2009
TUMORE DELLA MAMMELLA
SOPRAVVIVENZA RELATIVA A 5 ANNI DALLA DIAGNOSI
Casi diagnosticati 1995-99
Fonte: Sant M. et al. EJC 2009. EUROCARE-4
Breast cancer descriptive epidemiology
data
• Mortality is decreasing
• Incidence tends to decrease in young
women
• Survival is improving
• High geographical differences