the influence of ejaculation and abstinence on urinary flow rates luca cindolo cosimo de nunzio petros sountoulides athanasios bantis andrea tubaro luigi schips background • uroflowmetry : the commonest tool to evaluate LUTS • reliability and sensitivity questionable • possible confounders recent catheterization level of stress and anxiety menstrual phase patients coffee sexual position intake activity question? Does the ejaculation improve the urinary flow rate in young healthy men? methods young men, healthy, volounteers pvr, iief, ipss, suprapubic prostate US + daily uroflowmetry for 22 consecutive days !!!! ejaculations only at days 0, 6 and 22 (T0, T6 and T22) (flow measured 2-6 hours after ej) methods • adherence to the protocol: self-reported • sexual intercourse vs masturbation : not investigated • comparison of the changes before and after ejaculation and during the period of sexual abstinence • all uroflowmetry charts were checked by LC, blinded to the subject’s real sexual status • all subjects were instructed to freely void without abdominal pressure and to repeat if <150 ml results • 18 evaluable volounteers (9 excluded) • age 27.4 y ipss 0.1 iief 64 • prostatic volume 24.7ml; 0ml pvr • flows collected: 414 results Distribution of Q max values over the time results conclusions • Q max increases after ejaculation (about ~3 ml/sec!!! ~15%) • … decreases during the abstinence • In the future men with LUTS should be studied in order to undestand if the ejaculation is a confounder especially in evaluating the results of therapies (PDE5i, alpha blockers)