ILARIA DANDO
curriculum vitae
PERSONAL DETAILS
Name: Ilaria Dando
Date of birth: February 19, 1984
Place of birth: Verona, Italy
Status: Married
Nationality: Italian
e-mail: [email protected]
EDUCATION AND QUALIFICATION
- 2003: School-leaving certificate at “Scientific Liceo Galileo Galilei” of Verona;
- 2003-2006: Bachelor Degree in Agro-Industrial Biotechnology, University of Verona;
graduating mark 110/110 cum laude;
graduation thesis title: “Genotipic analisys of three T-DNA mutants for the study of
cGMP in Arabidopsis thaliana”.
- 2006-2009: Master Degree in Molecular-Industrial Biotechnology, University of
Verona;
graduating mark 110/110 cum laude;
graduation thesis title: “Antipoliferative synergism of gemcitabine and rimonabant in
pancreatic adenocarcinoma cell lines”.
- 2010-2012: PhD student in Bioscience, University of Verona; tutor: Prof. Marta Palmieri;
project title: “Cannabinoids inhibit energetic metabolism and induce AMPK
dependent autophagy in pancreatic cancer cells”.
Defence date: May 24, 2013
- November 2011: winner of the “Young Graduate Award” from Annual Congress of the
Italian Association of Cell Culture.
- 2013: post-doctoral granted by Nanomed-Cariverona, in Prof. Marta Palmieri laboratory.
- 2013: Nominated by Prof. Marta Palmieri “Expert in the field of Biochemistry of
Movement”, Department of Neurological and Movement Sciences, Degree in
Motory Activity and Sports Sciences, University of Verona.
LABORATORY EXPERIENCES
- 2006: three months as undergraduate student in the laboratory of Prof. Massimo
Delledonne, Molecular Biology, University of Verona;
- 2008-2009: one year and a half as undergraduate student in the laboratory of Prof. Marta
Palmieri, Biological Chemistry, University of Verona.
- 2010-2012: three years as PhD student in Biosciences in the laboratory of Prof. Marta
Palmieri, Biological Chemistry, University of Verona.
-2011: three months as visiting scientist in the laboratory of System Biology of Prof. Lewis
Cantley at Beth Israel Deaconess Medical Center, Harvard University, Boston, MA,
U.S.A.
- 2012: five months as visiting scientist in the laboratory of Prof. David Tuveson at Cancer
Research UK, Cambridge Research Institute, University of Cambridge, UK and Cold
Spring Harbor Laboratory, NY, U.S.A., working on the creation of genetically
modified mouse models to study intestine neuroendocrine tumors. The project was
founded by “Caring for Carcinoid Foundation”.
- January 15-16, 2013: I attended the “VeVO 2100 high frequency ultrasound training on
abdominal imaging” at University of Verona.
- 2013: post-doc in the laboratory of Prof. Marta Palmieri; project title: “Study of
anti-tumoral compounds in pancreatic adenocarcinoma through the use of
Nanotechnological Approaches”. During this period I used nude mice and I
improved the knowledges, about the usage of animal models, obtained during the
period in Dr. Tuveson laboratory.
POSTER IN CONGRESS
- “Synergistic anti-proliferative effect of gemcitabine and cannabinoids in pancreatic
adenocarcinoma cell lines” M. Donadelli, T. Zaniboni, I. Dando, C. Costanzo, and M.
Palmieri.
American Association for Cancer Research, 13th-16th September 2009, San Diego, La Jolla,
USA.
- “Gemcitabine and cannabinoids synergistically inhibit pancreatic adenocarcinoma
cell growth by ROS-mediated autophagic cell death” I. Dando, T. Zaniboni, M.
Donadelli, C. Costanzo, E. Dalla Pozza, and M. Palmieri.
• 23° National Congress of Biochemistry, 8th-11th June 2010, Brallo di Pregola,Pavia, Italy.
• 55° National Congress of the Italian Society of Biochemistry and Molecular Biology
(SIB), 14th-17th September 2010, University of Milan, Italy.
• 23° Annual Congress of the Italian Association of Cell Culture, 24th-26th November
2010, Tumour National Institute, Milan, Italy.
• 36° FEBS Congress, 25th-30th June 2011, Lingotto Conference Center, Turin, Italy.
- “Gemcitabine response in pancreatic adenocarcinoma cells is synergistically
enhanced by dithiocarbammate derivates” E. Dalla Pozza, M. Donadelli, C. Costanzo, T.
Zaniboni, I. Dando, and M. Palmieri
23° Annual Congress of the Italian Association of Cell Culture, 24th-26th November
2010, Tumour National Institute, Milan, Italy.
- “Modeling Carcinoid in Mice” I. Dando, H. Tiriac, A. Scarpa, and D.A. Tuveson
Translational Topics in Cancer Genetics and Biology, 10th October 2012, Banbury
Conference Center, Cold Spring Harbor, NY.
- “ Autophagy induced by p53-reactivating molecules protects pancreatic cancer cells
from apoptosis” Claudia Fiorini, Chiara Padroni, Ilaria Dando, Elisa Dalla Pozza, Chiara
Costanzo, Marta Palmieri, and Massimo Donadelli.
2012 The First Australian p53 Workshop, 19th-21st November 2012, Peter MacCallum
Cancer Center, Melbourne.
- “Isolation and drug sensitivity of cancer stem cells obtained from pancreatic
adenocarcinoma cell lines” E. Dalla Pozza, J. Brandi, C. Costanzo, I. Dando, D. Cecconi,
M. Donadelli, and M. Palmieri.
25° Annual Congress of the Italian Association of Cell Culture, 21st-23rd November
2012, Palermo, Italy
- “UCP2 inhibition triggers ROS-dependent nuclear translocation of GAPDH and
autophagic cell death synergistically inhibiting pancreatic cancer cell proliferation
with gemcitabine” I. Dando, E. Dalla Pozza, C. Fiorini, C. Padroni, C. Costanzo, M.
Palmieri, and M. Donadelli,
25° Annual Congress of the Italian Association of Cell Culture, 21st-23rd November
2012, Palermo, Italy
- “Comparative proteomic and phosphoproteomic profiling of pancreatic
adenocarcinoma cell treated with CB1 or CB2 agonists” J. Brandi, I. Dando, M.
Palmieri, M. Donadelli, D. Cecconi.
VIII ItPA (Italian Proteomics Association) Annual Congress, 18th-21st June 2013, Padova,
Italy.
TALK AT SCIENTIFIC CONGRESS
- “Gemcitabine and cannabinoids synergistically inhibit pancreatic adenocarcinoma
cell growth by ROS-mediated autophagic cell death”
• 55° National of the Italian Society of Biochemistry and Molecular Biology (SIB), 16th
September 2010, University of Milan, Italy.
• 23° Annual Congress of the Italian Association of Cell Culture, 24th November 2010,
Tumour National Institute, Milan, Italy.
PAPERS
- “Gemcitabine response in pancreatic adenocarcinoma cells is synergistically
enhanced by dithiocarbamate derivatives”, Dalla Pozza E, Donadelli M, Costanzo C,
Zaniboni T, Dando I, Franchini M, Arpicco S, Scarpa A, Palmieri M.. Free Radic Biol
Med., 50 (2011), 926-933.
- “Gemcitabine/cannabinoid combination triggers autophagy in pancreatic cancer cells
through a ROS-mediated mechanism” M Donadeli, I Dando, T Zaniboni, C Costanzo, E
Dalla Pozza, MT Scupoli, A Scarpa, S Zappavigna, M Marra, A Abruzzese, M Bifulco, M
Caraglia and M Palmieri. Cell Death and Disease, 2011, 2, e152.
- “Role of mitochondrial uncopling protein 2 in cancer cell resistance to gemcitabine”,
E Dalla Pozza, C Fiorini, I Dando, M Menegazzi, A Sgarbossa, C Costanzo, M Palmieri and
M Donadelli. Biochim Biophys Acta, 1823 (2012), 1856-1863.
- “Expression of the antiapoptotic protein BAG3 is a feature of pancreatic
adenocarcinoma and its overexpression is associated with poorer survival”, A Rosati,
S Bersani, F Tavano, E Dalla Pozza, M Palmieri, V De Laurenzi, R Franco, G
Scognamiglio, R Palaia, A Fontana, P Di Sebastiano, M Donadelli, I Dando, JP Medema, F
Dijik, L Welling, F Di Mola, R Pezzilli, MC Turco, A Scarpa. The American Journal of
Pathology, Vol. 181, No. 5, 2012.
- “Autophagy induced by p53-reactivating molecules protects pancreatic cancer cells
from apoptosis” C Fiorini, M Menegazzi, C Padroni, I Dando, E Dalla Pozza, A
Gregorelli, C Costanzo, M Palmieri and M Donadelli. Apoptosis, 2013, 18: 337-346.
- “UCP2 inhibition triggers ROS-dependent nuclear translocation of GAPDH and
autophagic cell death in pancreatic adenocarcinoma cells” I Dando, C Fiorini, E Dalla
Pozza, C Padroni, C Costanzo, M Palmieri and M Donadelli. Biochim Biophys Acta, 1833,
(2013), 672-679.
- “Targeting gemcitabine containing liposomes to CD44 expressing pancreatic
adenocarcinoma cells causes an increase in the antitumoral activity” E Dalla Pozza, C
Lerda, C Costanzo, M Donadelli, I Dando, E Zoratti, MT Scupoli, S Beghelli, A Scarpa, E
Fattal, S Arpicco and M Palmieri. Biochim Biophys Acta Biomembranes, 1818 (2013),
1396-1404
- “Comparative proteomic and phosphoproteomic profiling of pancreatic
adenocarcinoma cells treated with CB1 or CB2 agonists”, J Brandi#, I Dando#, M
Palmieri, M Donadelli and D Cecconi. Electrophoresis, 2013, 34, 1359-1368
#
equally contributed to this work
- “Cannabinoids inhibit energetic metabolism and induce AMPK-dependent autophagy
in pancreatic cancer cells” I Dando, M Donadelli, C Costanzo, E Dalla Pozza, A
D’Alessandro, L Zolla and M Palmieri. Cell Death and Disease, 2013, 4, e664; doi:
10.1038/cddis.2013.151
- “Hyaluronic acid-coated liposomes for active targeting of gemcitabine” S Arpicco, C.
Lerda, E Dalla Pozza, C Costanzo, N Tsapis, B Stella, M Donadelli, I Dando, E Fattal, L
Cattel, M Palmieri. European Journal of Pharmaceutics and Biopharmaceutics, 2013 Jun 18.
pii: S0939-6411(13)00221-X. doi: 10.1016/j.ejpb.2013.06.003.
- “UCP2, a mitochondrial protein regulated at multiple levels” M Donadelli, I Dando, C
Fiorini and M Palmieri. Cellular and Molecular Life Sciences, 2013, doi: 10.1007/
s00018-013-1407-0.
LANGUAGES AND OTHER SKILLS
- Italian
Native Italian speaker;
- English
Very good level both written and oral;
- Computer
Good PC skills: Windows, Microsoft Office, Internet Explorer, Excel, Word, Access, Power
Point. I obtained the “European Computer Driving License” (ECDL).