Scheda personale
Cognome: d’Ischia
Nome: Marco
Ruolo: Professore Ordinario
Laboratorio/Studio: Dipartimento di Scienze Chimiche, Università degli Studi di
Napoli Federico II
Indirizzo ufficio: Via Cintia, 80126 Napoli
N.Telefono ufficio: 081-674132
Fax:
E-Mail: [email protected], [email protected]
Giorno e orario di ricevimento:
Pagina web personale: https://www.docenti.unina.it/marco.d'ischia
Biografia Breve
(descrizione breve)
Marco d’Ischia è Professore Ordinario di Chimica Organica presso l’Università di
Napoli Federico II, Dipartimento di Scienze Chimiche, dove coordina un gruppo di
ricerca di chimica di composti organici bioattivi e sistemi molecolari funzionali
innovativi bioispirati. L’attività scientifica è documentata da oltre 240 pubblicazioni
(Luglio 2015, circa 5000 citazioni, h-index 37 secondo ISI WoS) su riviste
internazionali. Attualmente è: 1) componente del Direttivo della Divisione di
Chimica Organica della Società Chimica Italiana; 2) componente del Scientific
Committee della Ischia Advanced School of Organic Chemistry (IASOC
Conference); 3) coordinatore scientifico dell’European Network on Melanin Research
(EuMelaNet); 4) Componente dell'Editorial Board della Rivista Open Access
Biomimetics (MDPI). Per le ricerche nel campo della chimica delle melanine e della
pigmentazione ha ricevuto nel 2011 la Raper Medal dalla International Federation of
Pigment Cell Societies e dalla European Society for Pigment Cell Research.
Biografia breve in inglese
(descrizione breve)
Marco d'Ischia is Professor of Organic Chemistry at the University of Naples
Ferderico II. At present he leads the group of Bioactive and Bio-inspired Product
Chemistry at the Department of Chemical Sciences. He is the author or co-author of
ca. 240 publications (as of September 2015, with over 5000 citations, h-index = 37 source ISI WoS) in the fields of organic and bioorganic chemistry and biochemistry.
Currently he is: 1) member of the Executive Committee of the Italian Chemical
Society, Division of Organic Chemistry (term of office 2011-2016); 2) Member of the
Scientific Committee of the Ischia Advanced School of Organic Chemistry (IASOC
Conference); 3) Scientific coordinator of the European Network for Melanin Research
(EuMelaNet); 4) Member of the Editorial Board of Biomimetics (ISSN 2313-7673),
an open access Journal of MDPI Publishing. In 2011 he was awarded the Raper
Medal by the International Federation of Pigment Cell Societies and the European
Society for Pigment Cell Research.
Biografia Estesa
Marco d’Ischia ha conseguito la laurea in Chimica con lode presso l’Università di
Napoli nel 1981. Nel 1984 ha vinto il concorso per ricercatore universitario
prendendo servizio presso l’Università di Napoli. Nel 1992 è diventato Professore
Associato di Chimica Organica. Dal 2001 è Professore Ordinario di Chimica Organica
presso l’Università di Napoli Federico II, Dipartimento di Scienze Chimiche, dove
coordina un gruppo di ricerca di chimica di composti organici bioattivi e sistemi
molecolari funzionali innovativi bioispirati. Dal 2001 al 2008 è stato Presidente del
Consiglio di Corso di Laurea in Chimica presso l’Università di Napoli Federico II.
L’attività scientifica è documentata da oltre 240 pubblicazioni (Luglio 2015, circa
5000 citazioni, h-index 37 secondo ISI WoS) su riviste internazionali, reviews e
capitoli di libro nel campo della chimica organica e bioorganica. E’ stato Guest
Editor di uno “special issue” della rivista internazionale Pigment Cell Research
pubblicato nel 2003 (Pigment Cell Research 16(5), 433-604, 2003), è autore di due
capitoli per la serie Comprehensive Heterocyclic Chemistry -III (CHEC-III), Editor in
Chief Professor Alan Katritzky, dal titolo “Pyrroles and their benzo derivatives:
Structure” e “Pyrroles and their benzo derivatives: Applications” (2008) ed è autore
del testo didattico “La Chimica Organica in Laboratorio” (Piccin Ed., 2002).
Gli interessi di ricerca sono incentrati principalmente su tematiche riguardanti la
chimica della melanine e di materiali funzionali bioispirati relazionati; la chimica
delle catecolammine in relazione ai meccanismi di degenerazione neuronale; il
meccanismo d’azione di composti naturali bioattivi e farmacologicamente attivi, in
particolare antiossidanti e antinitrosanti fenolici in alimenti di origine vegetale; le
proprietà e reattività di composti eterociclici; l’ossidazione, la nitrosazione e la
nitrazione di proteine, lipidi, carboidrati ed altre biomolecole in relazione ai
meccanismi di danno cellulare indotto da stress ossidativo; la chimica e il ruolo
biologico di sostanze naturali bioattive contenenti zolfo e di composti eterociclici.
Il Prof. d’Ischia è membro dell’European Society for Pigment Cell Research,
dell’American Chemical Society e della Società Chimica Italiana. E’ stato ed è
coordinatore nazionale o responsabile scientifico di unità in progetti PRIN e di tre
progetti finanziati dal Ministero della Salute. Per lo svolgimento di tali ricerche il
Prof. d'Ischia si è avvalso e/o si avvale della collaborazione di gruppi attivi in vari
istituti di ricerca nazionali e internazionali. Ha partecipato, in qualità di Presidente o
Segretario Scientifico, all'organizzazione di numerosi convegni e scuole di chimica
nazionali e internazionali tra cui: International Colloquium on Neuromelanin and
Parkinson's Disease" (Sorrento, 1993); Primo Convegno Italo Giapponese di Chimica
Organica (JISOC), (Napoli, 1999); 10th meeting of the European Society for Pigment
Cell Research (Roma, 2001), Giornate di chimica delle sostanze naturali (Salerno,
2003), I e II edizione della Scuola delle Sostanze Naturali e di Chimica Biorganica
“L.Minale” (Salerno 2003, Napoli 2005) della Società Chimica Italiana, XXIII
Convegno Nazionale della Società Chimica Italiana (Sorrento 5-10 luglio 2009).
E’ stato componente del Council dell'European Society for Pigment Cell Research;
Editor della rivista internazionale Pigment Cell Research. E’ stato componente
dell’Advisory Board dell’International Pigment Cell Conference (Bordeaux, 2011).
Attualmente Marco d’Ischia è: 1) componente del Direttivo della Divisione di
Chimica Organica della Società Chimica Italiana; 2) componente del Scientific
Committee della Ischia Advanced School of Organic Chemistry (IASOC
Conference); 3) coordinatore scientifico dell’European Network on Melanin Research
(EuMelaNet); 4) Componente dell'Editorial Board della Rivista Open Access
Biomimetics (MDPI). Per le ricerche nel campo della chimica delle melanine e della
pigmentazione ha ricevuto nel 2011 la Raper Medal dalla International Federation of
Pigment Cell Societies e dalla European Society for Pigment Cell Research.
Biografia Estesa in inglese
Marco d'Ischia graduated in Chemistry with Laude at the University of Naples in
1981. He earned a faculty position in the same university in 1984 and then rose
through the ranks: in 1992 he was made Associate Professor of Organic Chemistry,
and in 2001 Professor of Organic Chemistry. At present he leads the group of
Bioactive and Bio-inspired Product Chemistry at the Department of Chemical
Sciences of Naples University Federico II. He was Director of Chemistry Courses at
Naples University (2001-2008).
He is the author or co-author of ca. 240 publications (as of September 2015, with
over 5000 citations, h-index = 37 -source ISI WoS) in the fields of organic and
bioorganic chemistry and biochemistry, chiefly research papers on peer-reviewed
international journals but also reviews and book chapters. In particular, he has
contributed two chapters for the Comprehensive Heterocyclic Chemistry -III book
series (Alan Katritzky, Ed.); has been Guest Editor of a special issue of the
international journal Pigment Cell Research (Pigment Cell Research 16(5), 433-604,
2003); and has edited an undergraduate student textbook on experimental organic
chemistry (Piccin, 2002).
Marco d'Ischia's current interests centre on the chemistry of melanins and related
bionspired functional materials, including polydopamine, for application in organic
electronics and bioelectronics; the design and mechanism of action of phenolic
antioxidants and antinitrosating agents; the oxidative chemistry of catecholamine
neurotransmitters; the oxidation, nitrosation and nitration of biomolecules in relation
to oxidative stress-related pathologies; the chemistry and biological roles of sulfurcontaining natural products and heterocyclic compounds.
He is member of the European Society for Pigment Cell Research and of the
American Chemical Society. He has been national coordinator or principal
investigator in various projects funded by Italian MIUR (PRIN), Ministry of Health
and Regione Campania. These projects were partly realized with the collaboration of
several national and international scientific institutions.
He organized several international meetings including the International Symposium
on Neuromelanin and Parkinson's Disease (Sorrento, 1993), the first Japanese-Italian
Symposium on Organic Chemistry (Naples, 1999), the Luigi Minale School of
Natural Products and Biorganic Chemistry, Italian Chemical Society (Salerno 2003;
Naples, 2005). He was in the International Advisory Committee of the International
Pigment Cell Conference held in Bordeaux (2011). He was Session Chairman at the
48th EUCHEM conference on stereochemistry, Bürgenstock, Switzerland, May 2013.
Marco d'Ischia has been member of the Council of the European Society for Pigment
Cell Research (ESPCR), Regional Editor of the international journal Pigment Cell
Research, and member of the editorial board of the Pigment Cell Research Bulletin.
Currently Marco d’Ischia is: 1) member of the Executive Committee of the Italian
Chemical Society, Division of Organic Chemistry (term of office 2011-2016); 2)
Member of the Scientific Committee of the Ischia Advanced School of Organic
Chemistry (IASOC Conference); 3) Scientific coordinator of the European Network
for Melanin Research (EuMelaNet); 4) Member of the Editorial Board of
Biomimetics (ISSN 2313-7673), an open access Journal of MDPI Publishing.
In 2011 he was awarded the Raper Medal by the International Federation of Pigment
Cell Societies and the European Society for Pigment Cell Research.
Elenco delle Pubblicazioni (selezione dal periodo 2010-settembre 2015)
(specificare se completa o parziale)
Melanins and melanogenesis: from pigment cells to human health and technological
applications
d'Ischia, Marco; Wakamatsu, Kazumasa; Cicoira, Fabio; Di Mauro, Eduardo; GarciaBorron, Jose Carlos; Commo, Stephane; Galvan, Ismael; Ghanem, Ghanem; Kenzo,
Koike; Meredith, Paul; et al
Pigment Cell & Melanoma Research (2015), 28(5), 520-544.
Boosting, probing and switching-off visible light-induced photocurrents in eumelaninporous silicon hybrids
Pinna, Andrea; Simbula, Fabrizio; Marongiu, Daniela; Pezzella, Alessandro; d'Ischia,
Marco; Mula, Guido.
RSC Advances (2015), 5(70), 56704-56710.
Trichocyanines: a Red-Hair-Inspired Modular Platform for Dye-Based One-Time-Pad
Molecular Cryptography.
Leone, Loredana; Pezzella, Alessandro; Crescenzi, Orlando; Napolitano, Alessandra;
Barone, Vincenzo; d'Ischia, Marco
ChemistryOpen (2015), 4(3), 370-377.
Melanin-Inspired Organic Electronics: Electroluminescence in Asymmetric
Triazatruxenes
Manini, Paola; Criscuolo, Valeria; Ricciotti, Laura; Pezzella, Alessandro; Barra,
Mario; Cassinese, Antonio; Crescenzi, Orlando; Maglione, Maria Grazia; Tassini,
Paolo; Minarini, Carla; et al
ChemPlusChem (2015), 80(6), 919-927
Tailoring melanins for bioelectronics: polycysteinyldopamine as an ion conducting
redox-responsive polydopamine variant for pro-oxidant thin films
Della Vecchia, Nicola Fyodor; Marega, Riccardo; Ambrico, Marianna; Iacomino,
Mariagrazia; Micillo, Raffaella; Napolitano, Alessandra; Bonifazi, Davide; d'Ischia,
Marco
Journal of Materials Chemistry C: Materials for Optical and Electronic
Devices (2015), 3(25), 6525-6531.
From commercial tyrosine polymers to a tailored polydopamine platform: concepts,
issues and challenges en route to melanin-based bioelectronics
Ambrico, Marianna; Ambrico, Paolo F.; Ligonzo, Teresa; Cardone, Antonio; Cicco,
Stefania R.; d'Ischia, Marco; Farinola, Gianluca M.
Journal of Materials Chemistry C: Materials for Optical and Electronic
Devices (2015), 3(25), 6413-6423.
Resveratrol-based benzoselenophenes with an enhanced antioxidant and chain
breaking capacity
Tanini, Damiano; Panzella, Lucia; Amorati, Riccardo; Capperucci, Antonella; Pizzo,
Elio; Napolitano, Alessandra; Menichetti, Stefano; d'Ischia, Marco
Organic & Biomolecular Chemistry (2015), 13(20), 5757-5764.
A water-soluble eumelanin polymer with typical polyelectrolyte behaviour by
triethyleneglycol N-functionalization
Cicco, Stefania R.; Ambrico, Marianna; Ambrico, Paolo F.; Talamo, Maurizio
Mastropasqua; Cardone, Antonio; Ligonzo, Teresa; Di Mundo, Rosa; Giannini,
Cinzia; Sibillano, Teresa; Farinola, Gianluca M.; et al
Journal of Materials Chemistry C: Materials for Optical and Electronic
Devices (2015), 3(12), 2810-2816.
Dopamine-Based Coatings and Hydrogels: Toward Substitution-Related StructureProperty Relationships
Cui, Jiaxi; Iturri, Jagoba; Paez, Julieta; Shafiq, Zahid; Serrano, Cristina; d'Ischia,
Marco; del Campo, Aranzazu
Macromolecular Chemistry and Physics (2014), 215(24), 2403-2413.
Polydopamine and Eumelanin: From Structure-Property Relationships to a Unified
Tailoring Strategy
d'Ischia, Marco; Napolitano, Alessandra; Ball, Vincent; Chen, Chun-Teh; Buehler,
Markus J.
Accounts of Chemical Research (2014), 47(12), 3541-3550.
Stem cell-compatible eumelanin biointerface fabricated by chemically controlled solid
state polymerization
Pezzella, Alessandro; Barra, Mario; Musto, Anna; Navarra, Angelica; Alfe, Michela;
Manini, Paola; Parisi, Silvia; Cassinese, Antonio; Criscuolo, Valeria; d'Ischia, Marco
Materials Horizons (2015), 2(2), 212-220.
Artificial Biomelanin: Highly Light-Absorbing Nano-Sized Eumelanin by
Biomimetic Synthesis in Chicken Egg White
della Vecchia, Nicola Fyodor; Cerruti, Pierfrancesco; Gentile, Gennaro; Errico, Maria
Emanuela; Ambrogi, Veronica; D'Errico, Gerardino; Longobardi, Sara; Napolitano,
Alessandra; Paduano, Luigi; Carfagna, Cosimo; et al
Biomacromolecules (2014), 15(10), 3811-3816.
A Photoresponsive Red-Hair-Inspired Polydopamine-Based Copolymer for Hybrid
Photocapacitive Sensors
Ambrico, Marianna; Della Vecchia, Nicola Fyodor; Ambrico, Paolo F.; Cardone,
Antonio; Cicco, Stefania R.; Ligonzo, Teresa; Avolio, Roberto; Napolitano,
Alessandra; d'Ischia, Marco
Advanced Functional Materials (2014), 24(45), 7161-7172.
Ultraviolet-Induced Fluorescence of Polydopamine-Coated Emulsion Droplets
Quignard, Sandrine; d'Ischia, Marco; Chen, Yong; Fattaccioli, Jacques
ChemPlusChem (2014), 79(9), 1254-1257.
Superior Photoprotective Motifs and Mechanisms in Eumelanins Uncovered
Corani, Alice; Huijser, Annemarie; Gustavsson, Thomas; Markovitsi, Dimitra;
Malmqvist, Per-Aake; Pezzella, Alessandro; d'Ischia, Marco; Sundstroem, Villy
Journal of the American Chemical Society (2014), 136(33), 11626-11635.
Tris Buffer Modulates Polydopamine Growth, Aggregation, and Paramagnetic
Properties
Della Vecchia, Nicola Fyodor; Luchini, Alessandra; Napolitano, Alessandra;
D'Errico, Gerardino; Vitiello, Giuseppe; Szekely, Noemi; d'Ischia, Marco; Paduano,
Luigi
Langmuir (2014), 30(32), 9811-9818.
Towards Eumelanin@Zeolite Hybrids: Pore-Size-Controlled 5,6-Dihydroxyindole
Polymerization
Prasetyanto, Eko Adi; Manini, Paola; Napolitano, Alessandra; Crescenzi, Orlando;
d'Ischia, Marco; De Cola, Luisa
Chemistry - A European Journal (2014), 20(6), 1597-1601.
Unraveling the interplay of different contributions to the stability of the quinhydrone
dimer
Barone, V.; Cacelli, I.; Crescenzi, O.; d'Ischia, M.; Ferretti, A.; Prampolini, G.;
Villani, G.
RSC Advances (2014), 4(2), 876-885.
Atypical Structural and π-Electron Features of a Melanin Polymer That Lead to
Superior Free-Radical-Scavenging Properties
Panzella, Lucia; Gentile, Gennaro; D'Errico, Gerardino; Della Vecchia, Nicola F.;
Errico, Maria E.; Napolitano, Alessandra; Carfagna, Cosimo; d'Ischia, Marco
Angewandte Chemie, International Edition (2013), 52(48), 12684-12687.
Red-Hair-Inspired Chromogenic System Based on a Proton-Switched
Dehydrogenative Free-Radical Coupling
Leone, Loredana; Crescenzi, Orlando; Amorati, Riccardo; Valgimigli, Luca;
Napolitano, Alessandra; Barone, Vincenzo; d'Ischia, Marco
Organic Letters (2013), 15(19), 4944-4947.
5-S-Lipoylhydroxytyrosol, a Multidefense Antioxidant Featuring a Solvent-Tunable
Peroxyl Radical-Scavenging 3-Thio-1,2-dihydroxybenzene Motif
Quick View Other Sources
Amorati, Riccardo; Valgimigli, Luca; Panzella, Lucia; Napolitano, Alessandra;
d'Ischia, Marco
Journal of Organic Chemistry (2013), 78(19), 9857-9864.
Free Radical Coupling of o-Semiquinones Uncovered
Pezzella, Alessandro; Crescenzi, Orlando; Panzella, Lucia; Napolitano, Alessandra;
Land, Edward J.; Barone, Vincenzo; d'Ischia, Marco
Journal of the American Chemical Society (2013), 135(32), 12142-12149
Irreversible evolution of eumelanin redox states detected by an organic
electrochemical transistor: en route to bioelectronics and biosensing
Tarabella, Giuseppe; Pezzella, Alessandro; Romeo, Agostino; D'Angelo, Pasquale;
Coppede, Nicola; Calicchio, Marco; d'Ischia, Marco; Mosca, Roberto; Iannotta,
Salvatore
Journal of Materials Chemistry B: Materials for Biology and
Medicine (2013), 1(31), 3843-3849.
Excited-State Proton-Transfer Processes of DHICA Resolved: From Sub-Picoseconds
to Nanoseconds
Corani, Alice; Pezzella, Alessandro; Pascher, Torbjoern; Gustavsson, Thomas;
Markovitsi, Dimitra; Huijser, Annemarie; d'Ischia, Marco; Sundstroem, Villy
Journal of Physical Chemistry Letters (2013), 4(9), 1383-1388.
Engineering polydopamine films with tailored behaviour for next-generation
eumelanin-related hybrid devices
Ambrico, Marianna; Ambrico, Paolo F.; Cardone, Antonio; Della Vecchia, Nicola F.;
Ligonzo, Teresa; Cicco, Stefania R.; Talamo, Maurizio Mastropasqua; Napolitano,
Alessandra; Augelli, Vincenzo; Farinola, Gianluca M.; et al
Journal of Materials Chemistry C: Materials for Optical and Electronic
Devices (2013), 1(5), 1018-1028.
Red Hair Benzothiazines and Benzothiazoles: Mutation-Inspired Chemistry in the
Quest for Functionality
Napolitano, Alessandra; Panzella, Lucia; Leone, Loredana; d'Ischia, Marco
Accounts of Chemical Research (2013), 46(2), 519-528.
Bottom-Up Approach to Eumelanin Photoprotection: Emission Dynamics in Parallel
Sets of Water-Soluble 5,6-Dihydroxyindole-Based Model Systems
Corani, Alice; Huijser, Annemarie; Iadonisi, Alfonso; Pezzella, Alessandro;
Sundstroem, Villy; dIschia, Marco
Journal of Physical Chemistry B (2012), 116(44), 13151-13158.
Building-Block Diversity in Polydopamine Underpins a Multifunctional EumelaninType Platform Tunable Through a Quinone Control Point
Della Vecchia, Nicola F.; Avolio, Roberto; Alfe, Michela; Errico, Maria E.;
Napolitano, Alessandra; d'Ischia, Marco
Advanced Functional Materials (2013), 23(10), 1331-1340.
Glycosylated Eumelanin Building Blocks by Thioglycosylation of 5,6Diacetoxyindole with an Expedient Selenium-Based Dynamic-Mixture Methodology
Adinolfi, Matteo; d'Ischia, Marco; Iadonisi, Alfonso; Leone, Loredana; Pezzella,
Alessandro; Valerio, Silvia
European Journal of Organic Chemistry (2012), 2012(23), 4333-4338,
The Δ2,2'-Bi(2H-1,4-benzothiazine) Structural Motif of Red Hair Pigments Revisited:
Photochromism and Acidichromism in a Unique Four-State System
Leone, Loredana; Crescenzi, Orlando; Napolitano, Alessandra; Barone, Vincenzo;
d'Ischia, Marco
European Journal of Organic Chemistry (2012), 2012(27), 5136-5140,
Eumelanin buildup on the nanoscale: Aggregate growth/assembly and visible
absorption development in biomimetic 5,6-dihydroxyindole polymerization.
Arzillo, Marianna; Mangiapia, Gaetano; Pezzella, Alessandro; Heenan, Richard K.;
Radulescu, Aurel; Paduano, Luigi; d'Ischia, Marco
Biomacromolecules (2012), 13(8), 2379-2390.
A melanin-inspired pro-oxidant system for dopa(mine) polymerization: mimicking the
natural casing process
Greco, Giorgia; Panzella, Lucia; Gentile, Gennaro; Errico, Maria Emanuela;
Carfagna, Cosimo; Napolitano, Alessandra; d'Ischia, Marco
Chemical Communications (Cambridge, United Kingdom) (2011), 47(37), 1030810310
5,6-Dihydroxyindole Chemistry: Unexplored Opportunities Beyond Eumelanin
d'Ischia, Marco; Napolitano, Alessandra; Pezzella, Alessandro
European Journal of Organic Chemistry (2011), 2011(28), 5501-5516.
π-Electron Manipulation of the 5,6-Dihydroxyindole/Quinone System by 3Alkynylation: Mild Acid-Mediated Entry to (Cross)-Conjugated Scaffolds and
Paradigms for Medium-Tunable Chromophores
Capelli, Luigia; Crescenzi, Orlando; Manini, Paola; Pezzella, Alessandro; Barone,
Vincenzo; d'Ischia, Marco
Journal of Organic Chemistry (2011), 76(11), 4457-4466.
Uncovering the structure of human red hair pheomelanin:
benzothiazolylthiazinodihydroisoquinolines as key building blocks
Greco, Giorgia; Panzella, Lucia; Verotta, Luisella; d'Ischia, Marco; Napolitano,
Alessandra
Journal of Natural Products (2011), 74(4), 675-682.
First synthetic entry to the trimer stage of 5,6-dihydroxyindole polymerization: orthoalkynylaniline-based access to the missing 2,7':2',7''-triindole
Capelli, Luigia; Manini, Paola; Pezzella, Alessandro; d'Ischia, Marco
Organic & Biomolecular Chemistry (2010), 8(19), 4243-4245
UV-Dissipation Mechanisms in the Eumelanin Building Block DHICA
Huijser, Annemarie; Pezzella, Alessandro; Hannestad, Jonas K.; Panzella, Lucia;
Napolitano, Alessandra; d'Ischia, Marco; Sundstroem, Villy
ChemPhysChem (2010), 11(11), 2424-2431.
Cyclic Structural Motifs in 5,6-Dihydroxyindole Polymerization Uncovered:
Biomimetic Modular Buildup of a Unique Five-Membered Macrocycle
Arzillo, Marianna; Pezzella, Alessandro; Crescenzi, Orlando; Napolitano, Alessandra;
Land, Edward J.; Barone, Vincenzo; d'Ischia, Marco
Organic Letters (2010), 12(14), 3250-3253
Indicare afferenza a laboratori o gruppi di ricerca della Scuola
Indicare attività di ricerca
(descrizione breve o elenco degli ambiti/parole chiave)
Chimica della melanine e di materiali funzionali bioispirati relazionati; chimica delle
catecolammine in relazione ai meccanismi di degenerazione neuronale; meccanismo
d’azione di composti naturali bioattivi e farmacologicamente attivi, in particolare
antiossidanti e antinitrosanti fenolici in alimenti di origine vegetale; l’ossidazione, la
nitrosazione e la nitrazione di proteine, lipidi, carboidrati ed altre biomolecole in
relazione ai meccanismi di danno cellulare indotto da stress ossidativo; la chimica e il
ruolo biologico di sostanze naturali bioattive contenenti zolfo e di composti
eterociclici.
Indicare attività di ricerca (In Inglese)
(descrizione breve o elenco degli ambiti/parole chiave)
Chemistry of melanins and related bionspired functional materials, including
polydopamine, for application in organic electronics and bioelectronics; design and
mechanism of action of phenolic antioxidants and antinitrosating agents; oxidative
chemistry of catecholamine neurotransmitters; the oxidation, nitrosation and nitration
of biomolecules in relation to oxidative stress-related pathologies; chemistry and
biological roles of sulfur-containing natural products and heterocyclic compounds.
Allegare fotografia (formato jpg)