Emergenze-Urgenze in Cardiochirurgia Cattedra di Cardiochirurgia UNIVERSITA’ DEGLI STUDI DI FIRENZE Modality of the Surgical Procedure • Exigen or Emergent salvage immediately!!! (Tamponade, RCA, Massive haemorragy….) • Emergent: just possible (operation performed immediately on referral to surgeon or before the beginning of the next working day) • Urgent: between 12-24 h (operation performed at or after the beginning of the next working day but the patient must absolutely be kept in hospital before surgery) • Elective Cattedra di Cardiochirurgia UNIVERSITA’ DEGLI STUDI DI FIRENZE U-E is a Risk Factor in CS Non-elective Surgery modality is an independent Risk Factor in all scoring systems: – Parsonnet – Higgins (Cleveland Clinic) – STS – NNE OR – VA (Veteran Affairs) – EuroSCORE Cattedra di Cardiochirurgia UNIVERSITA’ DEGLI STUDI DI FIRENZE = 1.5 to 7.1 Preoperative estimation of risk of mortality, cerebrovascular accident, and mediastinitis, developed by the Northern New England Cardiovascular Disease Study Group. (Eagle KA, et al: ACC/AHA guidelines for CABG. J Am Coll Cardiol 1999; 34:1262.) Cattedra di Cardiochirurgia UNIVERSITA’ DEGLI STUDI DI FIRENZE European System for Cardiac Operative Risk Evaluation Cattedra di Cardiochirurgia UNIVERSITA’ DEGLI STUDI DI FIRENZE Operative mortality for elective, urgent, emergency, and salvage procedures for primary operations and reoperations for mitral vavlular replacements. (Data used with permission from Society of Thoracic Surgeons.) Cattedra di Cardiochirurgia UNIVERSITA’ DEGLI STUDI DI FIRENZE Risk Factors for Hospital Mortality in Aortic Surgery Risk factor p-value (range) Emergent operation 000–.0017 NYHA Age .0001–.015 .01–.045 CPB time <.001–.018 Dissection <.001–.04 Concomitant CABG .001–.0014 Previous cardiac operation <.001–.0068 Arch replacement <.001 Reoperation for bleed .0009–.032 Cattedra di Cardiochirurgia UNIVERSITA’ DEGLI STUDI DI FIRENZE Kaplan-Meier survival analysis for 675 patients with Marfan syndrome from ten different surgical centers according to the urgency of the procedure. (Gott VL, et al: Replacement of the aortic root in patients with Marfan's syndrome. N Engl J Med 1999; 340:1307.) Cattedra di Cardiochirurgia UNIVERSITA’ DEGLI STUDI DI FIRENZE Re-operation CABG: Mortality Risk • • • • elective reoperations urgent reoperations emergency reoperations "salvage" reoperations 5.2% 7.4% 13.5% 40.7% There is clearly a major increment in risk associated with emergency reoperations, a larger increment than has existed for patients undergoing primary surgery. (Data from the Society of Thoracic Surgeons for the year 1997) Cattedra di Cardiochirurgia UNIVERSITA’ DEGLI STUDI DI FIRENZE Determinant Factors for Risk in E-U • Patient related • Patology related • Surgical-Anesthetical procedures related Cattedra di Cardiochirurgia UNIVERSITA’ DEGLI STUDI DI FIRENZE Postoperative Mortality Preoperative Hemoglobin % Mortality 40 30 20 n=1958 10 0 6 7 8 9 10 11 Hemaglobin g/dl Carson et al. Lancet 1996;348:1055. Cattedra di Cardiochirurgia UNIVERSITA’ DEGLI STUDI DI FIRENZE 12 >12 Critical preoperative conditions Cattedra di Cardiochirurgia UNIVERSITA’ DEGLI STUDI DI FIRENZE Pathology needing non-elective Cardiac Surgery • Traumatology/Iatrogenic • Non elective Ischaemic or valvular/prostheses surgery • Acute Aortic Diseases • RCA Cattedra di Cardiochirurgia UNIVERSITA’ DEGLI STUDI DI FIRENZE Surgical/Anesthetical Procedures in non elective conditions “Life saving” • Sub-optimal • Incomplete • Inadeguate Cattedra di Cardiochirurgia UNIVERSITA’ DEGLI STUDI DI FIRENZE