CURRICULUM VITAE
FORMATO EUROPEO/EUROPEAN FORMAT
INFORMAZIONI PERSONALI/
PERSONAL INFORMATION
Nome, Cognome/Name, Surname
Indirizzo/Address
Via, numero civico, c.a.p., città,
nazione/ House number, street
name, postcode, city, country
Telefono/Telephone
Fax
E-mail
Sito web/Website
Nazionalità/Nationality
Luogo e data di nascita/ Place and
Date of birth
Andrea
Natali
Via
Brodolini,
26
56122
Pisa
Italy
+39‐050‐525069
+39‐050‐553235
[email protected]
‐
Italian
Pisa,
20‐February‐1961
ESPERIENZA PROFESSIONALE
/WORK EXPERIENCE
In ordine di data /Dates (from – to)
[Iniziare con le più recenti ed
elencare separatamente ciascun
incarico ricoperto/ Add separate
entries for each relevant post
occupied, starting with the most
recent. ]
Nome e indirizzo del datore di lavoro
/ Name and address of employer
Tipo o settore di attività / Type of
business or sector
Funzione o posto occupato /
Occupation or position held
Principali mansion e responsabilità /
Main activities and responsibilities
Page 1 - Curriculum vitae
di [cognome] / of [surname]
2007-Today
1999-2007
1994-1999
Associate professor of Internal Medicine
Research Investigator University of Pisa
Research Investigator CNR Institute of Clinical Physiology
Università di Pisa, Lungarno Pacinotti 43, Pisa
Teaching, clinical activities and clinical investigation
Associate professor
Responsible for inpatient and outpatient clinic for metabolic diseases.
Andrea Natali
ISTRUZIONE E FORMAZIONE /
EDUCATION AND TRAINING
In ordine di data /Dates (from – to)
[Iniziare con le più recenti ed
elencare separatamente ciascun
corso frequentato con successo/ Add
separate entries for each relevant
course you have completed, starting
with the most recent. ]
Nome e tipo d’istituto di istruzione o
formazione / Name and type of
organisation providing education and
training
Principali materie e competenze
professionali apprese / Principal
subjects occupational skills covered
Certificato o diploma ottenuto /Title of
qualification awarded
Livello nella classificazione nazionale
o internazionale / Level in National
classification
1995 Specialty in Internal medicine
1990 Specialty in Nuclear medicine
1987 Degree in Medicine
University of Pisa
Clinical investigation and teaching in metabolic diseases
ATTIVITA’ DI RICERCA /
RESEARCH ACTIVITIES
Attuali campi di ricerca / Research
sectors
1)
epidemiology
and
pathophysiology
of
vascular
complications
in
diabetes
and
hypertension.
2)
pathophysiology
of
insulin
resistance
in
relation
to
cardiovascular
risk
factors
and
endothelial
dysfunction.
3)
pathophysiology
of
ß‐cell
dysfunction.
Recenti attività scientifiche/ Recent
Scientific Activities.
Participation to collaborative projects funded by EU agencies (FP5 EU
project RISC and the ongoing IMI initiative sponsored SUMMIT project).
Page 2 - Curriculum vitae
di [cognome] / of [surname]
Andrea Natali
Pubblicazioni/ Books and Articles last
7 years
Page 3 - Curriculum vitae
di [cognome] / of [surname]
1. Caraccio
N,
Natali
A,
Sironi
A,
Baldi
S,
Frascerra
S,
Dardano
A,
Monzani
F,
Ferrannini
E:
Muscle
metabolism
and
exercise
tolerance
in
subclinical
hypothyroidism:
a
controlled
trial
of
levothyroxine.
J
Clin
Endocrinol
Metab
90:4057‐4062,
2005
2. Mari
A,
Gastaldelli
A,
Natali
A,
Ostergard
T,
Schmitz
O,
Ferrannini
E:
Characterization
of
beta‐cell
function
impairment
in
first‐degree
relatives
of
type
2
diabetic
subjects:
modeling
analysis
of
24‐h
triple‐meal
tests.
Am
J
Physiol
Endocrinol
Metab
288:E541‐546,
2005
3. Natali
A,
Toschi
E,
Baldeweg
S,
Casolaro
A,
Baldi
S,
Sironi
AM,
Yudkin
JS,
Ferrannini
E:
Haematocrit,
type
2
diabetes,
and
endothelium‐dependent
vasodilatation
of
resistance
vessels.
Eur
Heart
J
26:464‐471,
2005
4. Basta
G,
Sironi
AM,
Lazzerini
G,
Del
Turco
S,
Buzzigoli
E,
Casolaro
A,
Natali
A,
Ferrannini
E,
Gastaldelli
A:
Circulating
soluble
receptor
for
advanced
glycation
end
products
is
inversely
associated
with
glycemic
control
and
S100A12
protein.
J
Clin
Endocrinol
Metab
91:4628‐4634,
2006
5. Femia
R,
Natali
A,
L'Abbate
A,
Ferrannini
E:
Coronary
Atherosclerosis
and
Alcohol
Consumption.
Angiographic
and
Mortality
Data.
Arterioscler
Thromb
Vasc
Biol,
2006
6. Manco
M,
Nolfe
G,
Calvani
M,
Natali
A,
Nolan
J,
Ferrannini
E,
Mingrone
G:
Menopause,
insulin
resistance,
and
risk
factors
for
cardiovascular
disease.
Menopause
13:809‐817,
2006
7. Muscelli
E,
Mari
A,
Natali
A,
Astiarraga
BD,
Camastra
S,
Frascerra
SD,
Holst
JJ,
Ferrannini
E:
Impact
of
incretin
hormones
on
{beta}‐
cell
function
in
subjects
with
normal
or
impaired
glucose
tolerance.
Am
J
Physiol
Endocrinol
Metab,
2006
8. Natali
A,
Ferrannini
E:
Effects
of
metformin
and
thiazolidinediones
on
suppression
of
hepatic
glucose
production
and
stimulation
of
glucose
uptake
in
type
2
diabetes:
a
systematic
review.
Diabetologia
49:434‐441,
2006
9. Natali
A,
Toschi
E,
Baldeweg
S,
Ciociaro
D,
Favilla
S,
Sacca
L,
Ferrannini
E:
Clustering
of
insulin
resistance
with
vascular
dysfunction
and
low‐grade
inflammation
in
type
2
diabetes.
Diabetes
55:1133‐1140,
2006
10. Baldi
S,
Frascerra
S,
Ferrannini
E,
Natali
A:
LDL
resistance
to
oxidation:
Effects
of
lipid
phenotype,
autologous
HDL
and
alanine.
Clin
Chim
Acta
379:95‐100,
2007
11. Ferrannini
E,
Balkau
B,
Coppack
SW,
Dekker
JM,
Mari
A,
Nolan
J,
Walker
M,
Natali
A,
Beck‐Nielsen
H:
Insulin
resistance,
insulin
response,
and
obesity
as
indicators
of
metabolic
risk.
J
Clin
Endocrinol
Metab
92:2885‐2892,
2007
12. Ferrannini
E,
Muscelli
E,
Natali
A,
Gabriel
R,
Mitrakou
A,
Flyvbjerg
A,
Golay
A,
Hojlund
K:
Association
of
fasting
glucagon
and
proinsulin
concentrations
with
insulin
resistance.
Diabetologia
50:2342‐2347,
2007
13. Neglia
D,
De
Caterina
A,
Marraccini
P,
Natali
A,
Ciardetti
M,
Vecoli
C,
Gastaldelli
A,
Ciociaro
D,
Pellegrini
P,
Testa
R,
Menichetti
L,
L'Abbate
A,
Stanley
WC,
Recchia
FA:
Impaired
myocardial
metabolic
reserve
and
substrate
selection
flexibility
during
stress
Andrea Natali
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
Page 4 - Curriculum vitae
di [cognome] / of [surname]
in
patients
with
idiopathic
dilated
cardiomyopathy.
Am
J
Physiol
Heart
Circ
Physiol
293:H3270‐3278,
2007
Lubrano
V,
Baldi
S,
Ferrannini
E,
L'Abbate
A,
Natali
A:
Role
of
thromboxane
A2
receptor
on
the
effects
of
oxidized
LDL
on
microvascular
endothelium
nitric
oxide,
endothelin‐1,
and
IL‐6
production.
Microcirculation
15:543‐553,
2008
Bonora
E,
Capaldo
B,
Perin
PC,
Del
Prato
S,
De
Mattia
G,
Frittitta
L,
Frontoni
S,
Leonetti
F,
Luzi
L,
Marchesini
G,
Marini
MA,
Natali
A,
Paolisso
G,
Piatti
PM,
Pujia
A,
Solini
A,
Vettor
R,
Bonadonna
RC:
Hyperinsulinemia
and
insulin
resistance
are
independently
associated
with
plasma
lipids,
uric
acid
and
blood
pressure
in
non‐
diabetic
subjects.
The
GISIR
database.
Nutr
Metab
Cardiovasc
Dis
18:624‐631,
2008
Natali
A,
Baldi
S,
Vittone
F,
Muscelli
E,
Casolaro
A,
Morgantini
C,
Palombo
C,
Ferrannini
E:
Effects
of
glucose
tolerance
on
the
changes
provoked
by
glucose
ingestion
in
microvascular
function.
Diabetologia
51:862‐871,
2008
Sesti
G,
Andreozzi
F,
Bonadonna
RC,
De
Mattia
G,
Leonetti
F,
Luzi
L,
Marini
MA,
Natali
A,
Vettor
R,
Bonora
E:
Impact
of
lowering
the
criterion
for
impaired
fasting
glucose
on
identification
of
individuals
with
insulin
resistance.
The
GISIR
database.
Diabetes
Metab
Res
Rev
24:130‐136,
2008
Gastaldelli
A,
Natali
A,
Vettor
R,
Corradini
SG:
Insulin
resistance,
adipose
depots
and
gut:
interactions
and
pathological
implications.
Dig
Liver
Dis
42:310‐319,
2010
Ferrannini
E,
Massari
M,
Nannipieri
M,
Natali
A,
Ridaura
RL,
Gonzales‐Villalpando
C:
Plasma
glucose
levels
as
predictors
of
diabetes:
the
Mexico
City
diabetes
study.
Diabetologia
52:818‐824,
2009
Natali
A,
Muscelli
E,
Casolaro
A,
Nilsson
P,
Melander
O,
Lalic
N,
Ferrannini
E,
Petrie
JR:
Metabolic
characteristics
of
prehypertension:
role
of
classification
criteria
and
gender.
J
Hypertens,
2009
Gall
WE,
Beebe
K,
Lawton
KA,
Adam
KP,
Mitchell
MW,
Nakhle
PJ,
Ryals
JA,
Milburn
MV,
Nannipieri
M,
Camastra
S,
Natali
A,
Ferrannini
E:
alpha‐hydroxybutyrate
is
an
early
biomarker
of
insulin
resistance
and
glucose
intolerance
in
a
nondiabetic
population.
PLoS
One
5:e10883,
2010
Di
Marco
S,
Boldrini
B,
Conti
U,
Marcucci
G,
Morgantini
C,
Ferrannini
E,
Natali
A:
Effects
of
GIK
(glucose‐insulin‐potassium)
on
stress‐induced
myocardial
ischaemia.
Clin
Sci
(Lond)
119:37‐44,
2010
Mari
A,
Tura
A,
Natali
A,
Laville
M,
Laakso
M,
Gabriel
R,
Beck‐
Nielsen
H,
Ferrannini
E:
Impaired
beta
cell
glucose
sensitivity
rather
than
inadequate
compensation
for
insulin
resistance
is
the
dominant
defect
in
glucose
intolerance.
Diabetologia
53:749‐756,
2010
Ferrannini
E,
Natali
A,
Muscelli
E,
Nilsson
PM,
Golay
A,
Laakso
M,
Beck‐Nielsen
H,
Mari
A:
Natural
history
and
physiological
determinants
of
changes
in
glucose
tolerance
in
a
non‐diabetic
population:
the
RISC
Study.
Diabetologia
54:1507‐1516,
2011
Andrea Natali
25. Rebelos
E,
Muscelli
E,
Natali
A,
Balkau
B,
Mingrone
G,
Piatti
P,
Konrad
T,
Mari
A,
Ferrannini
E:
Body
Weight,
Not
Insulin
Sensitivity
or
Secretion,
May
Predict
Spontaneous
Weight
Changes
in
Nondiabetic
and
Prediabetic
Subjects:
The
RISC
Study.
Diabetes
60:1938‐1945,
2011
26. Mari
A,
Tura
A,
Natali
A,
Anderwald
C,
Balkau
B,
Lalic
N,
Walker
M,
Ferrannini
E:
Influence
of
Hyperinsulinemia
and
Insulin
Resistance
on
In
Vivo
beta‐Cell
Function:
Their
Role
in
Human
beta‐Cell
Dysfunction.
Diabetes,
2011
(in
press)
27. Morgantini
C,
Natali
A,
Boldrini
B,
Imaizumi
S,
Navab
M,
Fogelman
AM,
Ferrannini
E,
Reddy
ST:
Anti‐inflammatory
and
antioxidant
properties
of
HDLs
are
impaired
in
type
2
diabetes.
Diabetes
60:2617‐2623,
2011
28. Morgantini
C,
Stea
F,
Boldrini
B,
Duranti
E,
Ghiadoni
L,
Natali
A:
Effect
of
mild
hyperisulinemia
on
conduit
vessel
endothelial
function:
role
of
noradrenergic
activation.
Journal
of
hypertension
30:720‐724,
2012
29. Natali
A,
Santini
E,
Delbarba
A,
Baldi
S,
Venturi
E,
Tulipani
A,
Nisoli
E,
Ferrannini
E:
Effects
of
short
and
prolonged
mild
intracellular
nitric
oxide
manipulations
on
various
aspects
of
insulin
secretion
in
INS‐1E
beta‐cells.
Experimental
and
clinical
endocrinology
&
diabetes
:
official
journal,
German
Society
of
Endocrinology
[and]
German
Diabetes
Association
120:210‐216,
2012
ULTERIORI INFORMAZIONI /
ADDITIONAL INFORMATION
Page 5 - Curriculum vitae
di [cognome] / of [surname]
Andrea Natali
TRATTAMENTO DEI DATI
PERSONALI, INFORMATIVA E
CONSENSO
Il D.Lgs. 30/6/2003, n. 196 “Codice in materia di protezione dei dati personali” regola il
trattamento dei dati personali, con particolare riferimento alla riservatezza, all’identità personale
e al diritto di protezione dei dati personali; l’interessato deve essere previamente informato del
trattamento .
La norma in considerazione intende come “trattamento” qualunque operazione o complesso di
operazioni concernenti la raccolta, la registrazione, l’organizzazione, la conservazione, la
consultazione, l’elaborazione, la modifica, la selezione, l’estrazione, il raffronto, l’utilizzo,
l’interconnessione, il blocco, la comunicazione, la diffusione, la cancellazione e la distruzione di
dati, anche se non registrati in una banca dati.
In relazione a quanto riportato, autorizzo il CNR al trattamento dei dati contenuti nel presente
curriculum vitae e nella documentazione della quale fa parte integrante
( barrare la casella)
Page 6 - Curriculum vitae
di [cognome] / of [surname]
Andrea Natali
x Si, acconsento