LUCA LAZZARI
CURRICULUM VITAE
Name and Surname:
Date and Place of birth:
Nationality:
Work Address:
Luca Lazzari
March 29, 1983; Moncalieri (Torino), Italy
Italian
Laboratory of Molecular Pharmacology,
Institute for Cancer Research and Treatment (IRCC)
Department of Oncological Sciences,
University of Torino Medical School
SP 142, km 3.95 10060 Candiolo (TO), Italy
Phone: (+39)011 9933210
E-mail: [email protected]
Education
December 2005:
Degree in Biological Sciences (Undergraduate degree, B.Sc. equivalent),
University of Torino, Italy
Final mark: 106/110
Thesis title: “Functional characterization of Arhgap12”; advisors: Prof.
Michele De Bortoli; Prof. Enzo Medico
July 2008:
Degree in Biomolecular Sciences (Advanced degree, M.Sc. equivalent),
University of Torino, Italy
Final mark: 110/110 cum laude
Thesis title: “Possible role of ROR1 pseudo-kinase receptor in cancer”;
advisors: Prof. Michele De Bortoli; Prof. Paolo M. Comoglio
January 2009 -now: Ph.D. in Cell Sciences and Technologies, Doctoral School in Molecular
Medicine, Department of Oncological Sciences, University of Torino, Italy.
Supervisor: Prof. Paolo M. Comoglio
December 2009:
Qualification to practice Biologist profession
Research Experience
2005-2007:
Undergraduate student at Laboratory of Functional Genomics (The
Oncogenomic Center – OGC); group leader: Prof. Enzo Medico
Institute for Cancer Research and Treatment (IRCC), Candiolo (Torino), Italy
Summer 2006:
selected candidate for CNIO International Undergraduate Summer Laboratory
Training Programme at Experimental Oncology Group, Molecular Oncology
Programme; group leader: Prof. Mariano Barbacid
Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain
2007-2008:
Undergraduate student at Molecular Oncology Division; group leader: Prof.
Paolo M. Comoglio
Institute for Cancer Research and Treatment (IRCC), Candiolo (Torino), Italy
2009-now:
Ph.D. student in Cell Sciences and Technologies, Doctoral School in Molecular
Medicine, University of Torino, Italy
Research is carrying out at Molecular Pharmacology Laboratory; group leader:
Prof. Livio Trusolino
Institute for Cancer Research and Treatment (IRCC), Candiolo (Torino), Italy
Fellowships
4-years Ph.D. fellowship of the Italian Ministry of Education, University and Research in 2009
Membership in Scientific Societies
2011 Young Member of Italian Society of Biochemistry and Molecular Biology (SIB, Società
Italiana di Biochimica e Biologia Molecolare)
2011 Young Member of Italian Cancer Society (SIC, Società Italiana di Cancerologia)
2011 Member of European Association for Cancer Research (EACR)
Pubblications
1. Gentile A., D’Alessandro L., Lazzari L., Martinoglio B., Bertotti A., Mira A., Lanzetti L., Comoglio
P.M. and Medico E.
“Met-driven invasive growth involves transcriptional regulation of Arhgap12”
Oncogene 2008, 27(42): 5590-5598
2. Benvenuti S., Lazzari L., Arnesano A., Li Chiavi G., Gentile A. and Comoglio P.M.
“Ron kinase trans-phosphorylation sustains MET oncogene addiction”
Cancer Research 2011, 71(5): 1945-1955
3. Gentile A., Lazzari L., Benvenuti S., Trusolino L. and Comoglio P.M.
“Ror1 is a pseudokinase that is crucial for Met-driven tumorigenesis”
Cancer Research 2011, 71(8): 3132-3141
Abstracts to international congresses
1. Gentile A., Lazzari L., D’Alessandro L., Medico E. and Comoglio P.M.
“Arhgap12: a negative regulator of Hepatocyte Growth Factor-driven invasive growth
identified by a novel gene trapping strategy”
Beatson International cancer conference - 24 years of Ras and human cancer
June 18-21, 2006 Glasgow, Scotland (UK)
2. Gentile A., Lazzari L., Martinoglio B., Martelli M.L. and Medico E.
“Arhgap12: a negative regulator of HGF-driven invasive growth identified by a novel gene
trapping strategy”
EMBO workshop - Stemness: the bright and the dark side. Normal and cancer stem cells
September 19-22, 2006 Catanzaro, Italy
3. Benvenuti S., Lazzari L., Gentile A. and Comoglio PM.
“RON trans-phosphorylation sustains addiction to the MET oncogene”
21st Meeting of the European Association for Cancer Research (EACR)
June 26-29, 2010 Oslo, Norway
4. Gentile A., Lazzari L., Benvenuti S., Trusolino L. and Comoglio PM.
“ROR1 is a pseudokinase involved in Met-driven tumorigenesis”
21st Meeting of the European Association for Cancer Research (EACR)
June 26-29, 2010 Oslo, Norway
5. Lazzari L., Gentile A., Benvenuti S., Trusolino L. and Comoglio P.M.
“ROR1 is a pseudo-kinase involved in MET-driven tumorigenesis”
Nature CNIO Cancer Symposium - Frontiers in Tumour Progression
October 24-27, 2010 Madrid, Spain
6. Lazzari L., Gentile A., Benvenuti S., Trusolino L. and Comoglio P.M.
“ROR1 is a pseudokinase that is crucial for MET-driven tumorigenesis”
FEBS Advanced Lecture Course on Translational Cancer Research
September 27-October 4, 2011 Algarve, Portugal
Attended Congresses and Course
4th IRCC International Cancer Conference - Invasive Growth: a Genetic Programme for Stem Cells
and Cancer, June 7-9, 2007 Candiolo (TO), Italy
EMBO Molecular Medicine Workshop - Invasive Growth: a Genetic Programme for Stem Cells and
Cancer, September 10-12, 2009 Torino, Italy
PerkinElmer Days at Molecular Biotechnology Center - Receptor Binding & Signal Transduction,
June 15, 2010 Torino, Italy
Nature CNIO Cancer Symposium - Frontiers in Tumour Progression, Ottobre 24-27, 2010 Madrid,
Spain
2011 IRCC International Conference - Molecular Clinical Oncology, May 26-28, 2011 Torino, Italy
FEBS Advanced Lecture Course on Translational Cancer Research, September 27-October 4, 2011
Hotel Porto Bay Falésia, Olhos D’agua, Algarve, Portugal
53rd SIC Annual Meeting – Back to the Future: Translating Cancer Research from Bedside to Bench
and Back, October 19-22, 2011 Torino, Italy